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  • Immunotherapy or Chemoimmunotherapy in Older Adults With Advanced Non–Small Cell Lung Cancer

    Yoko Tsukita, Takehiro Tozuka, Kohei Kushiro, Shinobu Hosokawa, Toshiyuki Sumi, Mao Uematsu, Osamu Honjo, Ou Yamaguchi, Tetsuhiko Asao, Jun Sugisaka, Go Saito, Jun Shiihara, Ryo Morita, Seigo Katakura, Takehiro Yasuda, Kakeru Hisakane, Eisaku Miyauchi, Satoshi Morita, Kunihiko Kobayashi, Hajime Asahina JAMA Oncology 10 (4), 439-, 2024-04-01

    <jats:sec id="ab-coi230082-4"><jats:title>Importance</jats:title><jats:p>Immune checkpoint inhibitor (ICI) plus chemotherapy combination treatment (ICI-chemotherapy) is now a standard treatment for …

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  • Income Level and Impaired Kidney Function Among Working Adults in Japan

    石村いしむら, 奈々なな, 井上いのうえ, ひろし輔, 丸山まるやま, 士行しこう, 中村なかむら, さやか, 近藤こんどう, なおおのれ JAMA Health Forum 5 (3), 2024-03

    [Importance] Chronic kidney disease (CKD) is a major public health issue, affecting 850 million people worldwide. Although previous studies have shown the association between socioeconomic status …

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  • Early Tecovirimat Treatment for Mpox Disease Among People With HIV

    Bruce Aldred, Robert H. Lyles, Jane Y. Scott, Daniel J. Gromer, Amalia Aldredge, Kimberly A. Workowski, Zanthia Wiley, Boghuma K. Titanji, Brittany Szabo, Anandi N. Sheth, Paulina A. Rebolledo, Minh Ly Nguyen, Vincent C. Marconi, Colleen F. Kelley, Sheetal Kandiah, Aley Kalapila, Jesse T. Jacob, Betsy Hall, Jonathan A. Colasanti, Emily J. Cartwright, Valeria D. Cantos JAMA Internal Medicine 184 (3), 275-, 2024-03-01

    <jats:sec id="ab-ioi230093-4"><jats:title>Importance</jats:title><jats:p>Despite a lack of effectiveness data in humans, tecovirimat was widely prescribed to people with HIV (PWH) with mpox during …

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  • 自動じどう運転うんてん安全あんぜんせい評価ひょうかかんする国際こくさい標準ひょうじゅん解説かいせつ

    中村なかむら 弘毅こうき JARI Research Journal 2024 (2), n/a-, 2024-02-09

    <p>国連こくれんWP29によると,「自動じどう運転うんてんしゃ運行うんこう設計せっけい領域りょういきにおいて合理ごうりてき予見よけんされる防止ぼうし可能かのう人身じんしん事故じこしょうじさせないこと」が安全あんぜん目標もくひょうとなる.この要件ようけん具体ぐたいするためISO 34502ではシナリオにもとづいた安全あんぜんせい評価ひょうか枠組わくぐみ定義ていぎしている.そこでほんほうではISO 34502の概要がいよう解説かいせつし,かくプロセスにたいして日本にっぽん自動車じどうしゃ工業こうぎょうかいおよびSAKURAプロジェクトから提案ていあんされた手法しゅほう紹介しょうかいする.また,関連かんれんする国際こくさい標準ひょうじゅん

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  • Lessons From the Mpox Response

    Demetre Daskalakis, Nikki Romanik, Ashish K. Jha JAMA 331 (5), 387-, 2024-02-06

    <jats:p>This Viewpoint discusses 3 key lessons from the mpox response that can help better manage infectious disease outbreaks in the future.</jats:p>

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  • Lead Extraction and Mortality Among Patients With Cardiac Implanted Electronic Device Infection

    Sean D. Pokorney, Lindsay Zepel, Melissa A. Greiner, Vance G. Fowler, Eric Black-Maier, Robert K. Lewis, Donald D. Hegland, Christopher B. Granger, Laurence M. Epstein, Roger G. Carrillo, Bruce L. Wilkoff, Chantelle Hardy, Jonathan P. Piccini JAMA Cardiology 8 (12), 1165-, 2023-12-01

    <jats:sec id="ab-hoi230049-4"><jats:title>Importance</jats:title><jats:p>Complete hardware removal is a class I recommendation for cardiovascular implantable electronic device (CIED) infection, but …

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  • Tislelizumab vs Sorafenib as First-Line Treatment for Unresectable Hepatocellular Carcinoma

    Shukui Qin, Masatoshi Kudo, Tim Meyer, Yuxian Bai, Yabing Guo, Zhiqiang Meng, Taroh Satoh, Donatella Marino, Eric Assenat, Songzi Li, Yaxi Chen, Frederic Boisserie, Ramil Abdrashitov, Richard S. Finn, Arndt Vogel, Andrew X. Zhu JAMA Oncology 9 (12), 1651-, 2023-12-01

    <jats:sec><jats:title>Importance</jats:title><jats:p>Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality, and additional first-line treatments are needed. The programmed …

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  • Red Blood Cell Transfusion

    Jeffrey L. Carson, Simon J. Stanworth, Gordon Guyatt, Stacey Valentine, Jane Dennis, Sara Bakhtary, Claudia S. Cohn, Allan Dubon, Brenda J. Grossman, Gaurav K. Gupta, Aaron S. Hess, Jessica L. Jacobson, Lewis J. Kaplan, Yulia Lin, Ryan A. Metcalf, Colin H. Murphy, Katerina Pavenski, Micah T. Prochaska, Jay S. Raval, Eric Salazar, Nabiha H. Saifee, Aaron A. R. Tobian, Cynthia So-Osman, Jonathan Waters, Erica M. Wood, Nicole D. Zantek, Monica B. Pagano JAMA 330 (19), 1892-, 2023-11-21

    <jats:sec id="ab-jsc230002-1"><jats:title>Importance</jats:title><jats:p>Red blood cell transfusion is a common medical intervention with benefits and harms.</jats:p></jats:sec><jats:sec …

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  • Teleworking, Parenting Stress, and the Health of Mothers and Fathers

    John James Parker, Craig F. Garfield, Clarissa D. Simon, Anne Bendelow, Marie E. Heffernan, Matthew M. Davis, Kristin Kan JAMA Network Open 6 (11), e2341844-, 2023-11-03

    <jats:p>This cross-sectional study examines the associations of telework during the COVID-19 pandemic with parents’ general health, changes to mental health, and parenting stress.</jats:p>

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