ARL1

ARL1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1UPT, 4DCN, 5EE5
Dynodwyr
Cyfenwau	ARL1, ARFL1, ADP ribosylation factor like GTPase 1
Dynodwyr allanol	OMIM: 603425 HomoloGene: 20319 GeneCards: ARL1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • nucleotide binding • GO:0010577 enzyme activator activity • GO:0006184 GTPase activity • protein domain specific binding • metal ion binding • GTP binding Cydrannau o'r gell • Golgi apparatus • Golgi membrane • intracellular anatomical structure • bilen • cytoplasm • trans-Golgi network • trans-Golgi network membrane • cytosol Prosesau biolegol • protein localization to Golgi apparatus • toxin metabolic process • activation of phospholipase D activity • retrograde transport, endosome to Golgi • Golgi organization • Golgi vesicle transport • intracellular protein transport • vesicle-mediated transport Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	400	n/a
Ensembl	ENSG00000120805	n/a
UniProt	P40616	n/a
RefSeq (mRNA)	NM_001301068 NM_001177	n/a
RefSeq (protein)	NP_001168 NP_001287997	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn ARL1 yw ARL1 a elwir hefyd yn ADP ribosylation factor like GTPase 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 12, band 12q23.2.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn ARL1.

• ARFL1

Llyfryddiaeth

• "Arfaptins are localized to the trans-Golgi by interaction with Arl1, but not Arfs. ". J Biol Chem. 2011. PMID 21239483.
• "Different ARF domains are required for the activation of cholera toxin and phospholipase D. ". J Biol Chem. 1995. PMID 7814376.
• "Structural Insights into Arl1-Mediated Targeting of the Arf-GEF BIG1 to the trans-Golgi. ". Cell Rep. 2016. PMID 27373159.
• "Rab4 orchestrates a small GTPase cascade for recruitment of adaptor proteins to early endosomes. ". Curr Biol. 2014. PMID 24835460.
• "Structural basis for membrane binding specificity of the Bin/Amphiphysin/Rvs (BAR) domain of Arfaptin-2 determined by Arl1 GTPase.". J Biol Chem. 2012. PMID 22679020.