CD1D

CD1D
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 4WO4, 1ZT4, 2PO6, 3HUJ, 3SDX, 3TZV, 3U0P, 3VWJ, 3VWK, 4EN3, 4LHU, 4MNG, 4MQ7, 4WW2
Dynodwyr
Cyfenwau	CD1D, CD1A, R3, R3G1, CD1d molecule
Dynodwyr allanol	OMIM: 188410 HomoloGene: 1337 GeneCards: CD1D
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • beta-2-microglobulin binding • lipopeptide binding • GO:0031493 histone binding • endogenous lipid antigen binding • lipid antigen binding • exogenous lipid antigen binding • cell adhesion molecule binding • GO:0001948, GO:0016582 protein binding Cydrannau o'r gell • cytoplasm • integral component of membrane • endosome • endoplasmic reticulum membrane • bilen • integral component of plasma membrane • cell surface • lysosomal membrane • basolateral plasma membrane • lysosome • endosome membrane • Cellbilen • Reticwlwm endoplasmig • extracellular space • external side of plasma membrane Prosesau biolegol • immune system process • T cell selection • heterotypic cell-cell adhesion • positive regulation of T cell proliferation • detection of bacterium • positive regulation of innate immune response • antigen processing and presentation, exogenous lipid antigen via MHC class Ib • innate immune response • GO:0022415 viral process • antigen processing and presentation, endogenous lipid antigen via MHC class Ib • regulation of immune response • positive regulation of T cell mediated cytotoxicity • GO:0046730, GO:0046737, GO:0046738, GO:0046736 immune response Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	912	n/a
Ensembl	ENSG00000158473	n/a
UniProt	P15813	n/a
RefSeq (mRNA)	NM_001766 NM_001319145 NM_001371761 NM_001371762 NM_001371763	n/a
RefSeq (protein)	NP_001306074 NP_001757 NP_001358690 NP_001358691 NP_001358692	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn CD1D yw CD1D a elwir hefyd yn CD1d molecule (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 1, band 1q23.1.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn CD1D.

• R3
• CD1A
• R3G1

Llyfryddiaeth

• "CD1d is a novel cell-surface marker for human monocytic myeloid-derived suppressor cells with T cell suppression activity in peripheral blood after allogeneic hematopoietic stem cell transplantation. ". Biochem Biophys Res Commun. 2018. PMID 29108995.
• "Blocking of CD1d Decreases Trypanosoma cruzi-Induced Activation of CD4-CD8- T Cells and Modulates the Inflammatory Response in Patients With Chagas Heart Disease. ". J Infect Dis. 2016. PMID 27368347.
• "The tumor antigen N-glycolyl-GM3 is a human CD1d ligand capable of mediating B cell and natural killer T cell interaction. ". Cancer Immunol Immunother. 2016. PMID 26969612.
• "The actin cytoskeleton modulates the activation of iNKT cells by segregating CD1d nanoclusters on antigen-presenting cells. ". Proc Natl Acad Sci U S A. 2016. PMID 26798067.
• "Increased Expression of Two Alternative Spliced Variants of CD1d Molecule in Human Gastric Cancer.". Iran J Immunol. 2015. PMID 26119195.