MKNK1

MKNK1
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 2HW6, 2Y9Q
Dynodwyr
Cyfenwau	MKNK1, MNK1, MAP kinase interacting serine/threonine kinase 1, MAPK interacting serine/threonine kinase 1
Dynodwyr allanol	OMIM: 606724 HomoloGene: 37838 GeneCards: MKNK1
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • transferase activity • nucleotide binding • protein kinase activity • calcium-dependent protein serine/threonine kinase activity • calmodulin binding • kinase activity • GO:0001948, GO:0016582 protein binding • calmodulin-dependent protein kinase activity • ATP binding • protein serine/threonine kinase activity • metal ion binding Cydrannau o'r gell • cytoplasm • cytosol • nucleoplasm • cnewyllyn cell Prosesau biolegol • GO:0007243 intracellular signal transduction • phosphorylation • protein phosphorylation • protein autophosphorylation • regulation of translation • GO:0035404 peptidyl-serine phosphorylation Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	8569	n/a
Ensembl	ENSG00000079277	n/a
UniProt	Q9BUB5	n/a
RefSeq (mRNA)	NM_001135553 NM_003684 NM_198973 NM_001377337 NM_001377338 NM_001377341 NM_001377342 NM_001377343 NM_001377373 NM_001377374 NM_001377375	n/a
RefSeq (protein)	NP_001129025 NP_003675 NP_945324 NP_001364266 NP_001364267 NP_001364270 NP_001364271 NP_001364272 NP_001364302 NP_001364303 NP_001364304	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search		n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn MKNK1 yw MKNK1 a elwir hefyd yn MAP kinase-interacting serine/threonine-protein kinase 1 a MAP kinase interacting serine/threonine kinase 1 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn ôl o gromosom dynol 1, band 1p33.

Cyfystyron

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn MKNK1.

• MNK1

Llyfryddiaeth

• "The C-terminal domain of Mnk1a plays a dual role in tightly regulating its activity. ". Biochem J. 2009. PMID 19650764.
• "Characterization of the activity of human MAP kinase-interacting kinase Mnk1b. ". Biochim Biophys Acta. 2007. PMID 17590453.
• "Translational control of human neutrophil responses by MNK1. ". J Leukoc Biol. 2013. PMID 23401599.
• "Contrasting roles of mitogen-activated protein kinases in cellular entry and replication of hepatitis C virus: MKNK1 facilitates cell entry. ". J Virol. 2013. PMID 23365451.
• "MNK1 kinase activity is required for abscission.". J Cell Sci. 2012. PMID 22454512.