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16 p, 3.7 MB

An epigenetic switch controls an alternative NR2F2 isoform that unleashes a metastatic program in melanoma / Davalos, Veronica (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Lovell, Claudia D. (New York University School of Medicine, USA) ; Von Itter, Richard (New York University School of Medicine, USA) ; Dolgalev, Igor (New York University Grossman School of Medicine, USA) ; Agrawal, Praveen (New York University Grossman School of Medicine, USA) ; Baptiste, Gillian (New York University Grossman School of Medicine, USA) ; Kahler, David J. (New York University Grossman School of Medicine, USA) ; Sokolova, Elena (New York University Grossman School of Medicine, USA) ; Moran, S (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Piqué, Laia (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Vega-Saenz de Miera, Eleazar (New York University School of Medicine, USA) ; Fontanals-Cirera, Barbara (New York University School of Medicine, USA) ; Karz, Alcida (New York University School of Medicine, USA) ; Tsirigos, Aristotelis (New York University Grossman School of Medicine, USA) ; Yun, Chi (New York University Grossman School of Medicine, USA) ; Darvishian, Farbod (New York University Grossman School of Medicine, USA) ; Etchevers, Heather C. (Aix-Marseille University, Marseille, France) ; Osman, Iman (New York University Grossman School of Medicine, USA) ; Esteller, M (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Schober, Markus (New York University School of Medicine, USA) ; Hernando, Eva (New York University Grossman School of Medicine, USA)
Metastatic melanoma develops once transformed melanocytic cells begin to de-differentiate into migratory and invasive melanoma cells with neural crest cell (NCC)-like and epithelial-to-mesenchymal transition (EMT)-like features. [...]
2023 - DOI (Digital Object Identifier)

10.1038/s41467-023-36967-2
Nature communications, Vol. 14 Núm. 1 (april 2023)

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