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1.
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12 p, 9.5 MB |
Single-cell transcriptomic profiling reveals a pathogenic role of cytotoxic CD4+ T cells in giant cell arteritis
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Carmona, Elio G. (Hospital Universitario San Cecilio (Granada)) ;
Callejas Rubio, Jose Luis (Hospital Universitario San Cecilio (Granada)) ;
Raya, Enrique (Hospital Universitario San Cecilio (Granada)) ;
Ríos-Fernández, Raquel (Hospital Universitario San Cecilio (Granada)) ;
Villanueva-Martín, Gonzalo (Institute of Parasitology and Biomedicine López-Neyra) ;
Cid, María (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Hernández-Rodríguez, José (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Ballestar, Esteban (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Timmermann, Bernd (Max Planck Institute for Molecular Genetics) ;
Ortego-Centeno, Norberto (Universidad de Granada. Departamento de Medicina) ;
Martín, Javier (Spanish National Research Council) ;
Márquez, Ana (Instituto de Parasitología y Biomedicina "López-Neyra")
Giant cell arteritis (GCA) is a systemic vasculitis mediated by an aberrant immunological response against the blood vessel wall. Although the pathogenic mechanisms that drive GCA have not yet been elucidated, there is strong evidence that CD4 T cells are key drivers of the inflammatory process occurring in this vasculitis. [...]
2024 -  10.1016/j.jaut.2023.103124
Journal of autoimmunity, Vol. 142 (january 2024) , p. 103124
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2.
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14 p, 1.2 MB |
GWAS for systemic sclerosis identifies multiple risk loci and highlights fibrotic and vasculopathy pathways
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López-Isac, Elena (Institute of Parasitology and Biomedicine López-Neyra) ;
Acosta-Herrera, Marialbert (Institute of Parasitology and Biomedicine López-Neyra) ;
Kerick, Martin (Institute of Parasitology and Biomedicine López-Neyra) ;
Assassi, Shervin (The University of Texas Health Science Center-Houston) ;
Satpathy, Ansuman (Stanford University) ;
Granja, Jeffrey (Stanford University) ;
Mumbach, Maxwell (Stanford University) ;
Beretta, Lorenzo (Referral Center for Systemic Autoimmune Diseases) ;
Simeón-Aznar, Carmen Pilar (Hospital Universitari Vall d'Hebron) ;
Carreira, Patricia E. (Hospital 12 de Octubre (Madrid)) ;
Ortego-Centeno, Norberto (Hospital Universitario San Cecilio (Granada)) ;
Castellvi, Ivan (Institut d'Investigació Biomèdica Sant Pau) ;
Bossini-Castillo, Lara (Wellcome Trust Sanger Institute (Regne Unit)) ;
Carmona, F. David (Universidad de Granada) ;
Orozco, Gisela (The University of Manchester) ;
Hunzelmann, Nicolas (University of Cologne) ;
Distler, Jörg H. W. (University of Erlangen-Nuremberg) ;
Franke, Andre (Christian-Albrechts-University of Kiel) ;
Lunardi, Claudio (Università degli Studi di Verona) ;
Moroncini, Gianluca (Università Politecnica delle Marche and Ospedali Riuniti) ;
Gabrielli, Armando (Università Politecnica delle Marche and Ospedali Riuniti) ;
de Vries-Bouwstra, Jeska (Leiden University Medical Center) ;
Wijmenga, Cisca (University of Groningen) ;
Koeleman, Bobby (University Medical Center Utrecht) ;
Nordin, Annika (Karolinska Institutet (Estocolm, Suècia)) ;
Padyukov, Leonid (Karolinska Institutet (Estocolm, Suècia)) ;
Hoffmann-Vold, Anna-Maria (Oslo University Hospital (Oslo, Noruega)) ;
Lie, Benedicte A. (University of Oslo and Oslo University Hospital) ;
Ríos, Raquel (Hospital Universitario San Cecilio (Granada)) ;
Callejas Rubio, Jose Luis (Hospital Universitario San Cecilio (Granada)) ;
Vargas-Hitos, José Antonio (Hospital Universitario Virgen de las Nieves (Granada)) ;
García-Portales, Rosa (Hospital Universitario Virgen de la Victoria (Màlaga, Andalusia)) ;
Camps, María Teresa (Hospital Regional Universitario de Málaga) ;
Fernández-Nebro, Antonio (Hospital Regional Universitario de Málaga) ;
González-Escribano, Maria Francisca (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
García-Hernández, Francisco Jose (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Castillo, María Jesús (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Aguirre, Mª Angeles (Hospital Reina Sofía/IMIBIC) ;
Gómez-Gracia, Inmaculada (Hospital Reina Sofía/IMIBIC) ;
Fernández-Gutiérrez, B. (San Carlos Clinic Hospital) ;
Rodríguez-Rodríguez, L. (San Carlos Clinic Hospital) ;
García de la Peña, Paloma (Madrid Norte Sanchinarro Hospital) ;
Vicente-Rabaneda, Esther Francisca (Hospital Universitario de la Princesa (Madrid)) ;
Andréu, José Luis (Puerta de Hierro Hospital-Majadahonda) ;
Fernández de Castro, Mónica (Puerta de Hierro Hospital-Majadahonda) ;
López-Longo, Francisco Javier (Hospital General Universitario Gregorio Marañón) ;
Martínez, Lina Patricia (Hospital General Universitario Gregorio Marañón) ;
Fonollosa, Vicenç (Hospital Universitari Vall d'Hebron) ;
Guillén, Alfredo Chávez (Hospital Universitari Vall d'Hebron) ;
Espinosa, Gerard (Hospital Clínic i Provincial de Barcelona) ;
Tolosa-Vilella, Carles (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Pros, Ana (Hospital del Mar (Barcelona, Catalunya)) ;
Rodríguez-Carballeira, M. (Hospital Universitari MútuaTerrassa) ;
Narváez, Francisco J. (Hospital Universitari de Bellvitge) ;
Rubio Rivas, Manuel (Hospital Universitari de Bellvitge) ;
Ortiz-Santamaría, None (Hospital Granollers) ;
Madroñero, A.B. (Hospital General Universitario San Jorge (Osca, Aragó)) ;
González-Gay, M.A. (Universidad de Cantabria) ;
Díaz, Bernardino (Hospital Universitario Central de Asturias) ;
Trapiella, L. (Hospital Universitario Central de Asturias) ;
Sousa, A. (Hospital Xeral-Complexo Hospitalario Universitario de Vigo) ;
Egurbide, María Victoria (Hospital Universitario de Cruces (Barakaldo, País Basc)) ;
Fanlo-Mateo, P. (Hospital Virgen del Camino (Pamplona)) ;
Sáez-Comet, L. (Hospital Universitario Miguel Servet (Saragossa)) ;
Díaz, F. (Hospital Universitario de Canarias (La Laguna)) ;
Hernández, None (Hospital Universitario de Canarias (La Laguna)) ;
Beltrán, E. (Hospital General Universitario de Valencia) ;
Román-Ivorra, J.A. (Hospital Universitari i Politècnic La Fe de València) ;
Grau, E. (Hospital Universitari i Politècnic La Fe de València) ;
Alegre-Sancho, Juan José (Hospital Universitari Doctor Peset (València)) ;
Freire, M. (Complexo Hospitalario Universitario de Vigo) ;
Blanco-García, F.J (INIBIC-Hospital Universitario A Coruña) ;
Oreiro, N. (INIBIC-Hospital Universitario A Coruña) ;
Witte, Torsten (Hannover Medical School) ;
Kreuter, A. (Ruhr University Bochum) ;
Riemekasten, G. (University of Lübeck) ;
Airò, Paolo (Service of Rheumatology and Clinic Immunology Spedali Civili) ;
Magro-Checa, César (Leiden University Medical Center) ;
Voskuyl, A.E. (Amsterdam UMC. University Medical Center) ;
Vonk, Madelon C. (Radboud University Nijmegen Medical Center) ;
Hesselstrand, Roger (Lund University) ;
Proudman, Susanna (Royal Adelaide Hospital and University of Adelaide) ;
Stevens, Wendy (St. Vincent's Hospital) ;
Nikpour, Mandana (The University of Melbourne at St. Vincent's Hospital) ;
Zochling, Jane M. (University of Tasmania) ;
Sahhar, Joanne (Monash Medical Centre) ;
Roddy, Janet (Cincinnati Children's Hospital Medical Center (CCHMC). Center for Fetal and Placental Research) ;
Nash, Peter (Sunshine Coast Rheumatology) ;
Tymms, Kathleen (Canberra Rheumatology) ;
Rischmueller, Maureen (The Queen Elizabeth Hospital) ;
Lester, S. (The Queen Elizabeth Hospital) ;
Vyse, Timothy (King's College London) ;
Herrick, Ariane (NIHR Manchester Biomedical Research Centre) ;
Worthington, Jane (The University of Manchester) ;
Denton, Christopher P (Royal Free and University College Medical School) ;
Allanore, Yannick (Paris Descartes University) ;
Brown, Matthew A. (Princess Alexandra Hospital) ;
Radstake, Timothy R. D. J. (University Medical Center Utrecht) ;
Fonseca, Carmen (Royal Free and University College Medical School) ;
Chang, Howard Y. (Stanford University) ;
Mayes, Maureen D (The University of Texas Health Science Center-Houston) ;
Martín, Javier (Institute of Parasitology and Biomedicine López-Neyra) ;
Universitat Autònoma de Barcelona
Systemic sclerosis (SSc) is an autoimmune disease that shows one of the highest mortality rates among rheumatic diseases. We perform a large genome-wide association study (GWAS), and meta-analysis with previous GWASs, in 26,679 individuals and identify 27 independent genome-wide associated signals, including 13 new risk loci. [...]
2019 - 10.1038/s41467-019-12760-y
Nature communications, Vol. 10 Núm. 1 (january 2019) , p. 4955
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1 p, 744.5 KB |
Author Correction : Impact of interstitial lung disease on the survival of systemic sclerosis with pulmonary arterial hypertension
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Guillén-Del-Castillo, Alfredo (Hospital Universitari Vall d'Hebron) ;
López-Meseguer, Manuel (Hospital Universitari Vall d'Hebron) ;
Fonollosa Pla, Vicent (Hospital Universitari Vall d'Hebron) ;
Sáez-Giménez, Berta (Hospital Universitari Vall d'Hebron) ;
Colunga-Argüelles, Dolores (Hospital Universitario Central de Asturias) ;
Revilla-López, Eva (Hospital Universitari Vall d'Hebron) ;
Rubio-Rivas, Manuel (Hospital Universitari de Bellvitge) ;
Ropero, María José Cristo (Hospital Universitario 12 de Octubre (Madrid)) ;
Argibay, Ana (Complexo Hospitalario Universitario de Vigo) ;
Barberà i Mir, Joan Albert (Hospital Clínic i Provincial de Barcelona) ;
Salas, Xavier Pla (Consorci Hospitalari de Vic) ;
Meñaca, Amaya Martínez (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ;
Vuelta, Ana Belén Madroñero (Hospital General Universitario San Jorge (Osca, Aragó)) ;
Padrón, Antonio Lara (Hospital Universitario de Canarias (La Laguna)) ;
Comet, Luis Sáez (Hospital Universitario Miguel Servet (Saragossa)) ;
Morera, Juan Antonio Domingo (Hospital Universitario Miguel Servet (Saragossa)) ;
González-Echávarri, Cristina (Hospital Universitario de Cruces (Barakaldo, País Basc)) ;
Mombiela, Teresa (Hospital General Universitario Gregorio Marañón) ;
Ortego-Centeno, Norberto (Hospital Universitario San Cecilio (Granada)) ;
González, Manuela Marín (Hospital Clínic Universitari (València)) ;
Tolosa-Vilella, Carles (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Blanco, Isabel (Hospital Clínic i Provincial de Barcelona) ;
Subías, Pilar Escribano (Centro de Investigación Biomédica en Red en Enfermedades Cardiovasculares) ;
Simeón-Aznar, Carmen Pilar (Hospital Universitari Vall d'Hebron)
To assess severity markers and outcomes of patients with systemic sclerosis (SSc) with or without pulmonary arterial hypertension (PAH-SSc/non-PAH-SSc), and the impact of interstitial lung disease (ILD) on PAH-SSc. [...]
2022 - 10.1038/s41598-022-17525-0
Scientific reports, Vol. 12 (july 2022)
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4.
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11 p, 1.2 MB |
Impact of interstitial lung disease on the survival of systemic sclerosis with pulmonary arterial hypertension
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Guillén-Del-Castillo, Alfredo (Hospital Universitari Vall d'Hebron) ;
López-Meseguer, Manuel (Hospital Universitari Vall d'Hebron) ;
Fonollosa Pla, Vicent (Hospital Universitari Vall d'Hebron) ;
Sáez-Giménez, Berta (Universitat Autònoma de Barcelona) ;
Colunga-Argüelles, Dolores (Hospital Universitario Central de Asturias) ;
Revilla-López, Eva (Hospital Universitari Vall d'Hebron) ;
Rubio-Rivas, Manuel (Hospital Universitari de Bellvitge) ;
Ropero, María José Cristo (Hospital Universitario 12 de Octubre (Madrid)) ;
Argibay, Ana (Complexo Hospitalario Universitario de Vigo) ;
Mir, Joan Albert Barberá (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ;
Salas, Xavier Pla (Consorci Hospitalari de Vic) ;
Meñaca, Amaya Martínez (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ;
Vuelta, Ana Belén Madroñero (Hospital General Universitario San Jorge (Osca, Aragó)) ;
Padrón, Antonio Lara (Hospital Universitario de Canarias (La Laguna)) ;
Comet, Luis Sáez (Hospital Universitario Miguel Servet (Saragossa)) ;
Morera, Juan Antonio Domingo (Hospital Universitario Miguel Servet (Saragossa)) ;
González-Echávarri, Cristina (Hospital Universitario de Cruces (Barakaldo, País Basc)) ;
Mombiela, Teresa (Hospital General Universitario Gregorio Marañón) ;
Ortego-Centeno, Norberto (Hospital Universitario San Cecilio (Granada)) ;
González, Manuela Marín (Hospital Clínic Universitari (València)) ;
Tolosa-Vilella, Carles (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Blanco, Isabel (Centro de Investigación Biomédica en Red de Enfermedades Respiratorias) ;
Subías, Pilar Escribano (Centro de Investigación Biomédica en Red en Enfermedades Cardiovasculares) ;
Simeón-Aznar, Carmen Pilar (Hospital Universitari Vall d'Hebron)
To assess severity markers and outcomes of patients with systemic sclerosis (SSc) with or without pulmonary arterial hypertension (PAH-SSc/non-PAH-SSc), and the impact of interstitial lung disease (ILD) on PAH-SSc. [...]
2022 - 10.1038/s41598-022-09353-z
Scientific reports, Vol. 12 (march 2022)
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5.
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9 p, 477.1 KB |
Registry of the Spanish Network for Systemic Sclerosis
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Simeón-Aznar, C. P. (Hospital Universitari Vall d'Hebron) ;
Fonollosa Pla, Vicent ;
Tolosa-Vilella, Carles (Hospital Universitari Vall d'Hebron) ;
Espinosa-Garriga, G. (Hospital Universitari Vall d'Hebron) ;
Campillo Grau, María Mercedes (Hospital Universitari Vall d'Hebron) ;
Ramos-Casals, M. (Hospital Universitari Vall d'Hebron) ;
García-Hernández, Francisco-José (Hospital Universitari Vall d'Hebron) ;
Castillo-Palma, M. J. (Hospital Universitari Vall d'Hebron) ;
Sánchez-Román, J. (Hospital Universitari Vall d'Hebron) ;
Callejas Rubio, Jose Luis (Hospital Universitari Vall d'Hebron) ;
Ortego-Centeno, Norberto (Hospital Universitari Vall d'Hebron) ;
Egurbide-Arberas, M. V. (Hospital Universitari Vall d'Hebron) ;
Trapiellla-Martínez, L. (Hospital Universitari Vall d'Hebron) ;
Caminal-Montero, Luis (Hospital Universitari Vall d'Hebron) ;
Sáez-Comet, L. (Hospital Universitari Vall d'Hebron) ;
Velilla-Marco, J. (Hospital Universitari Vall d'Hebron) ;
Camps-García, M. T. (Hospital Universitari Vall d'Hebron) ;
de Ramón-Garrido, E. (Hospital Universitari Vall d'Hebron) ;
Esteban-Marcos, E. M. (Hospital Universitari Vall d'Hebron) ;
Pallarés-Ferreres, L. (Hospital Universitari Vall d'Hebron) ;
Navarrete-Navarrete, N. (Hospital Universitari Vall d'Hebron) ;
Vargas-Hitos, J. A. (Hospital Universitari Vall d'Hebron) ;
de la Torre, R. Gómez (Hospital Universitari Vall d'Hebron) ;
Salvador-Cervello, G. (Hospital Universitari Vall d'Hebron) ;
Rios-Blanco, J. J. (Hospital Universitari Vall d'Hebron) ;
Vilardell-Tarrés, M. (Hospital Universitari Vall d'Hebron) ;
Universitat Autònoma de Barcelona
Systemic sclerosis (SSc) is a rare, multisystem disease showing a large individual variability in disease progression and prognosis. In the present study, we assess survival, causes of death, and risk factors of mortality in a large series of Spanish SSc patients. [...]
2015 - 10.1097/MD.0000000000001728
Medicine, Vol. 94 (october 2015)
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6.
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17 p, 1.6 MB |
Genetic Analysis with the Immunochip Platform in Behçet Disease. Identification of Residues Associated in the HLA Class I Region and New Susceptibility Loci
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Ortiz-Fernández, Lourdes (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Carmona, F. David (Instituto de Parasitología y Biomedicina "López-Neyra") ;
Montes-Cano, Marco-Antonio (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
García-Lozano, José-Raúl (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Conde-Jaldón, Marta (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Ortego-Centeno, Norberto (Hospital Universitario San Cecilio (Granada)) ;
Castillo, María Jesús (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Espinosa, Gerard (Hospital Universitari Clínic) ;
Graña, Jenaro (Complejo Hospitalario Universitario de A Coruña) ;
Sánchez-Bursón, Juan (Hospital Universitario Virgen de Valme (Sevilla, Andalusia)) ;
Juliá, María Rosa (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ;
Solans, Roser (Hospital Universitari Vall d'Hebron) ;
Blanco, Ricardo (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ;
Barnosi-Marín, Ana-Celia (Complejo Hospitalario Torrecárdenas (Almeria)) ;
Gómez de la Torre, Ricardo (Hospital Universitario Central de Asturias) ;
Fanlo, Patricia (Hospital Virgen del Camino (Pamplona)) ;
Rodríguez-Carballeira, Mónica (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ;
Rodriguez-Rodriguez, Luis (Hospital Clínico San Carlos (Madrid)) ;
Camps i Miró, Teresa (Hospital Regional Universitario de Málaga) ;
Castañeda, Santos (Instituto de Investigación Hospital Universitario de la Princesa) ;
Alegre-Sancho, Juan José (Hospital Universitari Doctor Peset (València)) ;
Martín, Javier (Instituto de Parasitología y Biomedicina "López-Neyra") ;
González-Escribano, María Francisca (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Universitat Autònoma de Barcelona
Behcet's disease (BD) is an immuno-mediated vasculitis in which knowledge of its etiology and genetic basis is limited. To improve the current knowledge, a genetic analysis performed with the Immunochip platform was carried out in a population from Spain. [...]
2016 - 10.1371/journal.pone.0161305
PloS one, Vol. 11 (august 2016)
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7.
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9 p, 1.1 MB |
Mutational profile of rare variants in inflammasome-related genes in Behçet disease : A Next Generation Sequencing approach
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Burillo-Sanz, Sergio (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Montes-Cano, Marco-Antonio (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
García-Lozano, José-Raúl (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Ortiz-Fernández, Lourdes (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Ortego-Centeno, Norberto (Hospital Universitario San Cecilio (Granada)) ;
García-Hernández, Francisco-José (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Espinosa, Gerard (Hospital Universitari Clínic) ;
Graña-Gil, Genaro (Complejo Hospitalario Universitario de A Coruña) ;
Sánchez-Bursón, Juan (Hospital Universitario Virgen de Valme (Sevilla, Andalusia)) ;
Juliá, María Rosa (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ;
Solans, Roser (Hospital Universitari Vall d'Hebron) ;
Blanco, Ricardo (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ;
Barnosi-Marín, Ana-Celia (Complejo Hospitalario Torrecárdenas (Almeria)) ;
Gómez de la Torre, Ricardo (Hospital Universitario Central de Asturias) ;
Fanlo, Patricia (Hospital Virgen del Camino (Pamplona)) ;
Rodríguez-Carballeira, Mónica (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ;
Rodriguez-Rodriguez, Luis (Hospital Clínico San Carlos (Madrid)) ;
Camps, Teresa (Hospital Regional Universitario de Málaga) ;
Castañeda, Santos (Instituto de Investigación Hospital Universitario de la Princesa) ;
Alegre-Sancho, Juan José (Hospital Universitari Doctor Peset (València)) ;
Martín, Javier (Instituto de Parasitología y Biomedicina "López-Neyra") ;
González-Escribano, María Francisca (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Universitat Autònoma de Barcelona
Behçet's disease (BD) is an immune-mediated systemic disorder with a well-established association with HLA class I and other genes. BD has clinical overlap with many autoinflammatory diseases (AIDs). [...]
2017 - 10.1038/s41598-017-09164-7
Scientific reports, Vol. 7 (august 2017)
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8.
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18 p, 1.4 MB |
Transancestral mapping and genetic load in systemic lupus erythematosus
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Langefeld, Carl D. (Department of Biostatistical Sciences, Wake Forest School of Medicine) ;
Ainsworth, Hannah C. (Department of Biostatistical Sciences, Wake Forest School of Medicine) ;
Graham, Deborah S. Cunninghame (Guy's and St Thomas' NHS Foundation Trust (Regne Unit)) ;
Kelly, Jennifer A. (Arthritis & Clinical Immunology Research Program, Oklahoma Medical Research Foundation) ;
Comeau, Mary E. (Department of Biostatistical Sciences, Wake Forest School of Medicine) ;
Marion, Miranda C. (Department of Biostatistical Sciences, Wake Forest School of Medicine) ;
Howard, Timothy D. (Center for Human Genomics and Personalized Medicine Research, Wake Forest School of Medicine) ;
Ramos, Paula S. (Department of Medicine, Medical University of South Carolina) ;
Croker, Jennifer A. (Universitat Autònoma de Barcelona. Facultat de Medicina) ;
Morris, David L. (Guy's and St Thomas' NHS Foundation Trust (Regne Unit)) ;
Sandling, Johanna K. (Department of Medical Sciences, Molecular Medicine and Science for Life Laboratory, Uppsala University) ;
Almlöf, Jonas Carlsson (Department of Medical Sciences, Molecular Medicine and Science for Life Laboratory, Uppsala University) ;
Acevedo-Vásquez, Eduardo M. (Departamento de Reumatología, Hospital G. Almenara y Facultad de Medicina, Universidad Nacional Mayor de San Marcos) ;
Alarcón, Graciela S. (Universitat Autònoma de Barcelona. Facultat de Medicina) ;
Babini, Alejandra M. (Hospital Italiano de Córdoba) ;
Baca, Vicente (Hospital de Pediatría) ;
Bengtsson, Anders A. (Department of Clinical Sciences, Rheumatology, Lund University) ;
Berbotto, Guillermo A. (Hospital Eva Perón) ;
Bijl, Marc (Department of Internal Medicine and Rheumatology, Martini Hospital) ;
Brown, Elizabeth E. (Universitat Autònoma de Barcelona. Facultat de Medicina) ;
Brunner, Hermine I. (Cincinnati Children's Hospital Medical Center) ;
Cardiel, Mario H. (Centro de Investigación Clínica de Morelia) ;
Catoggio, Luis (Hospital Italiano de Buenos Aires (Argentina)) ;
Cervera, Ricard (Hospital Clínic i Provincial de Barcelona) ;
Cucho-Venegas, Jorge M. (Universidad Nacional Mayor de San Marcos) ;
Dahlqvist, Solbritt Rantapää (Umeå University) ;
D'Alfonso, Sandra (University of Eastern Piedmont) ;
Da Silva, Berta Martins (Unidade Multidisciplinar em Investigação Biomédica/Instituto de Ciências Biomédicas de Abel Salazar-Universidade do Porto) ;
de la Rúa Figueroa, Iñigo (Hospital Universitario de Gran Canaria Dr. Negrín) ;
Doria, Andrea (University of Padua) ;
Edberg, Jeffrey C. (Universitat Autònoma de Barcelona. Facultat de Medicina) ;
Endreffy, Emőke (University of Szeged) ;
Esquivel-Valerio, Jorge A. (Universidad Autónoma de Nuevo León (Mèxic)) ;
Fortin, Paul R. (CHU de Québec Université Laval) ;
Freedman, Barry I. (Section on Nephrology, Wake Forest School of Medicine) ;
Frostegård, Johan (Karolinska Institutet) ;
García, Mercedes A. (Hospital Interzonal General de Agudos General San Martín) ;
de la Torre, Ignacio García (University of Guadalajara, Departamento de Fisiología) ;
Gilkeson, Gary S. (Department of Medicine, Medical University of South Carolina) ;
Gladman, Dafna D. (Toronto Western Hospital) ;
Gunnarsson, Iva (Karolinska University Hospital and Karolinska Institutet (Suècia)) ;
Guthridge, Joel M. (Oklahoma Medical Research Foundation) ;
Huggins, Jennifer L. (Cincinnati Children's Hospital Medical Center) ;
James, Judith A. (Departments of Medicine and Pathology, University of Oklahoma Health Sciences Center) ;
Kallenberg, Cees G. M. (University of Groningen) ;
Kamen, Diane L. (Department of Medicine, Medical University of South Carolina) ;
Karp, David R. (Department of Immunology, University of Texas SouthWestern Medical Center) ;
Kaufman, Kenneth M. (Cincinnati Children's Hospital Medical Center) ;
Kottyan, Leah C. (Cincinnati Children's Hospital Medical Center) ;
Kovács, László (University of Szeged) ;
Laustrup, Helle (Odense University Hospital (Dinamarca)) ;
Lauwerys, Bernard R. (Université catholique de Louvain) ;
Li, Quan-Zhen (Department of Immunology, University of Texas SouthWestern Medical Center) ;
Maradiaga-Ceceña, Marco A. (Hospital General de Culiacán) ;
Martín, Javier (Instituto de Parasitología y Biomedicina "López-Neyra") ;
McCune, Joseph M. (University of Michigan Medical Center) ;
McWilliams, David R. (Department of Biostatistical Sciences, Wake Forest School of Medicine) ;
Merrill, Joan T. (Arthritis & Clinical Immunology Research Program, Oklahoma Medical Research Foundation) ;
Miranda, Pedro (Centro de Estudios Reumatológicos, Santiago de Chile) ;
Moctezuma, José F. (Hospital General de México. Departamento de Reumatología) ;
Nath, Swapan K. (Arthritis & Clinical Immunology Research Program, Oklahoma Medical Research Foundation) ;
Niewold, Timothy B. (Department of Rheumatology, Mayo Clinic) ;
Orozco, Lorena (Instituto Nacional de Medicina Genómica) ;
Ortego-Centeno, Norberto (Hospital Universitario San Cecilio (Granada)) ;
Petri, Michelle (Department of Medicine, Johns Hopkins University School of Medicine) ;
Pineau, Christian A. (Rheumatology Division, McGill University) ;
Pons-Estel, Bernardo A. (Sanatorio Parque) ;
Pope, Janet (University of Western Ontario) ;
Raj, Prithvi (Department of Immunology, University of Texas SouthWestern Medical Center) ;
Ramsey-Goldman, Rosalind (Division of Rheumatology, Northwestern University Feinberg School of Medicine) ;
Reveille, John D. (The University of Texas) ;
Russell, Laurie P. (Department of Biostatistical Sciences, Wake Forest School of Medicine) ;
Sabio, José M. (Hospital Universitario Virgen de las Nieves (Granada)) ;
Aguilar-Salinas, Carlos Alberto (Instituto Nacional de Ciencias Médicas y Nutrición, Department of Endocrinology and Metabolism) ;
Scherbarth, Hugo R. (Unidad Reumatología y Enfermedades Autoinmunes H.I.G.A. Dr Alende Mar del Plata) ;
Scorza, Raffaella (University of Milan) ;
Seldin, Michael F. (Department of Biochemistry and Molecular Medicine, UC Davis School of Medicine) ;
Sjöwall, Christopher (Rheumatology Division of Neuro and Inflammation Sciences, Department of Clinical and Experimental Medicine, Linköping University) ;
Svenungsson, Elisabet (Karolinska University Hospital and Karolinska Institutet (Suècia)) ;
Thompson, Susan D. (Cincinnati Children's Hospital Medical Center) ;
Toloza, Sergio M. A. (Ministry of Health, San Fernando del Valle de Catamarca) ;
Truedsson, Lennart (Department of Laboratory Medicine, Section of Microbiology, Immunology and Glycobiology, Lund University) ;
Tusié-Luna, Teresa (Unidad de Biología Molecular y Medicina Genómica Instituto de Investigaciones Biomédicas) ;
Vasconcelos, Carlos (Universidade do Porto (Portugal)) ;
Vilá, Luis M. (University of Puerto Rico) ;
Wallace, Daniel J. (Department of Medicine, Cedars Sinai Medical Center) ;
Weisman, Michael H. (Department of Medicine, Cedars Sinai Medical Center) ;
Wither, Joan E. (Toronto Western Hospital) ;
Bhangale, Tushar (Human Genetics (San Francisco, Estats Units d'Amèrica)) ;
Oksenberg, Jorge (Department of Neurology and Institute of Human Genetics, University of California) ;
Rioux, John D. (Université de Montréal and the Montreal Heart Institute) ;
Gregersen, Peter K. (Center for Genomics & Human Genetics, The Feinstein Institute for Medical Research) ;
Syvänen, Ann-Christine (Department of Medical Sciences, Molecular Medicine and Science for Life Laboratory, Uppsala University) ;
Rönnblom, Lars (Department of Medical Sciences, Rheumatology, Uppsala University) ;
Criswell, Lindsey A. (Rosalind Russell/Ephraim P Engleman Rheumatology Research Center, Division of Rheumatology, UCSF School of Medicine) ;
Jacob, Chaim O. (Keck School of Medicine) ;
Sivils, Kathy L. (Oklahoma Medical Research Foundation (Estats Units d'Amèrica)) ;
Tsao, Betty P. (Department of Medicine, Medical University of South Carolina) ;
Schanberg, Laura E. (Department of Pediatrics, Duke University) ;
Behrens, Timothy W. (Human Genetics, Genentech Inc, South San Francisco) ;
Silverman, Earl D. (University of Toronto) ;
Alarcón-Riquelme, Marta E. (Karolinska Institutet (Estocolm, Suècia)) ;
Kimberly, Robert P. (Universitat Autònoma de Barcelona. Facultat de Medicina) ;
Harley, John B. (Cincinnati Children's Hospital Medical Center) ;
Wakeland, Edward K. (Department of Immunology, University of Texas SouthWestern Medical Center) ;
Graham, Robert R. (Human GeneticsSan Francisco (San Francisco, Estats Units d'Amèrica)) ;
Gaffney, Patrick M. (Arthritis & Clinical Immunology Research Program, Oklahoma Medical Research Foundation) ;
Vyse, Timothy (Guy's and St Thomas' NHS Foundation Trust (Regne Unit))
Systemic lupus erythematosus (SLE) is an autoimmune disease with marked gender and ethnic disparities. We report a large transancestral association study of SLE using Immunochip genotype data from 27,574 individuals of European (EA), African (AA) and Hispanic Amerindian (HA) ancestry. [...]
2017 - 10.1038/ncomms16021
Nature communications, Vol. 8 (07 2017)
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A TNFSF13B functional variant is not involved in systemic sclerosis and giant cell arteritis susceptibility
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González-Serna, David (Instituto de Parasitología y Biomedicina "López-Neyra") ;
Carmona, Elio G. (Instituto de Parasitología y Biomedicina "López-Neyra") ;
Ortego-Centeno, Norberto (Hospital Universitario San Cecilio (Granada)) ;
Simeón-Aznar, Carmen Pilar (Hospital Universitari Vall d'Hebron) ;
Solans, Roser (Hospital Universitari Vall d'Hebron) ;
Hernández-Rodríguez, José (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Tolosa, Carlos (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Castañeda, Santos (Instituto de Investigación Hospital Universitario de la Princesa) ;
Narváez, Javier (Institut d'Investigació Biomèdica de Bellvitge) ;
Martinez-Valle, Ferran (Hospital Universitari Vall d'Hebron) ;
Witte, Torsten (Hannover Medical School, Hannover) ;
Neumann, Thomas (Jena University Hospital (Alemanya)) ;
Holle, Julia (Vasculitis Clinic, Klinikum Bad Bramstedt & University Hospital of Schleswig Holstein, Bad Bramstedt) ;
Beretta, Lorenzo (Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico di Milano) ;
Boiardi, Luigi (Azienda Ospedaliera Arcispedale Santa Maria Nuova) ;
Emmi, Giacomo (University of Florence) ;
Cimmino, Marco Amedeo (University of Genova) ;
Vaglio, Augusto (Meyer Children's University Hospital) ;
Herrick, Ariane (The University of Manchester) ;
Denton, Christopher P. (Royal Free and University College Medical School) ;
Salvarani, Carlo (Azienda USL-IRCCS di Reggio Emilia and Università di Modena e Reggio Emilia) ;
Cid, María Cinta (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Morgan, Ann W. (University of Leeds and NIHR-Leeds Musculoskeletal Biomedical Research Unit) ;
Fonseca, Carmen (University College Medical School) ;
Gonzalez-Gay, MA (Instituto de Investigación Sanitaria Valdecilla (Santander, Cantàbria)) ;
Martín, Javier (Instituto de Parasitología y Biomedicina "López-Neyra") ;
Márquez, Ana (Hospital Universitario San Cecilio (Granada)) ;
Universitat Autònoma de Barcelona
The TNFSF13B (TNF superfamily member 13b) gene encodes BAFF, a cytokine with a crucial role in the differentiation and activation of B cells. An insertion-deletion variant (GCTGT→A) of this gene, leading to increased levels of BAFF, has been recently implicated in the genetic predisposition to several autoimmune diseases, including multiple sclerosis, systemic lupus erythematosus, and rheumatoid arthritis. [...]
2018 - 10.1371/journal.pone.0209343
PloS one, Vol. 13 (december 2018)
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13 p, 1.1 MB |
Influence of Antisynthetase Antibodies Specificities on Antisynthetase Syndrome Clinical Spectrum Time Course
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Cavagna, Lorenzo (University and IRCCS Policlinico S. Matteo Foundation of Pavia) ;
Trallero-Araguás, Ernesto (Hospital Universitari Vall d'Hebron) ;
Meloni, Federica (University and IRCCS Policlinico S. Matteo Foundation of Pavia) ;
Cavazzana, Ilaria (University and ASST Spedali Civili-Brescia) ;
Rojas-Serrano, Jorge (Instituto Nacional de Enfermedades Respiratorias (Mexico)) ;
Feist, Eugen (Charité - Universitätsmedizin Berlin) ;
Zanframundo, Giovanni (University and IRCCS Policlinico S. Matteo Foundation of Pavia) ;
Morandi, Valentina (University and IRCCS Policlinico S. Matteo Foundation of Pavia) ;
Meyer, Alain (Université de Strasbourg (França)) ;
Pereira da Silva, Jose Antonio (Centro Hospitalar e Universitário de Coimbra (Coimbra, Portugal)) ;
Matos Costa, Carlo Jorge (Centro Hospitalar e Universitário de Coimbra (Coimbra, Portugal)) ;
Molberg, Oyvind (Oslo University Hospital (Oslo, Noruega)) ;
Andersson, Helena (Oslo University Hospital (Oslo, Noruega)) ;
Codullo, Veronica (Cochin Hospital (París, França)) ;
Mosca, Marta (Azienda Ospedaliera Universitaria Pisana (Pisa, Itàlia)) ;
Barsotti, Simone (Azienda Ospedaliera Universitaria Pisana (Pisa, Itàlia)) ;
Neri, Rossella (Azienda Ospedaliera Universitaria Pisana (Pisa, Itàlia)) ;
Scirè, Carlo (Azienda Ospedaliero Universitaria S. Anna (Ferrara, Itàlia)) ;
Govoni, Marcello (Azienda Ospedaliero Universitaria S. Anna (Ferrara, Itàlia)) ;
Furini, Federica (Azienda Ospedaliero Universitaria S. Anna (Ferrara, Itàlia)) ;
Lopez-Longo, Francisco Javier (Hospital General Universitario Gregorio Marañón) ;
Martinez-Barrio, Julia (Hospital General Universitario Gregorio Marañón) ;
Schneider, Udo (Charité - Universitätsmedizin Berlin) ;
Lorenz, Hanns-Martin (University of Heidelberg (Heidelberg, Alemanya)) ;
Doria, Andrea (University of Padua (Padova, Itàlia)) ;
Ghirardello, Anna (University of Padua (Padova, Itàlia)) ;
Ortego-Centeno, Norberto (Hospital Universitario San Cecilio (Granada)) ;
Confalonieri, Marco (University Hospital of Cattinara (Trieste, Itàlia)) ;
Tomietto, Paola (University Hospital of Cattinara (Trieste, Itàlia)) ;
Pipitone, Nicolò (S. Maria Hospital-IRCCS (Reggio Emilia, Itàlia)) ;
Rodriguez Cambron, Ana Belen (Hospital Universitario Severo Ochoa) ;
Blázquez Cañamero, María Ángeles (Hospital Universitario Severo Ochoa) ;
Voll, Reinhard Edmund (Faculty of Medicine, University of Freiburg (Freiburg, Alemanya)) ;
Wendel, Sarah (Faculty of Medicine, University of Freiburg (Freiburg, Alemanya)) ;
Scarpato, Salvatore (Department of Rheumatology, Ospedale " Scarlato" ( Scafati, Itàlia)) ;
Maurier, Francois (Hopital Belle-Ile (Metz, França)) ;
Limonta, Massimiliano (ASST Papa Giovanni XXIII (Bergamo, Itàlia)) ;
Colombelli, Paolo (Ospedale di Treviglio (Treviglio, Itàlia)) ;
Giannini, Margherita (NHC Strasbourg, Université de Strasbourg (Strasbourg, França)) ;
Geny, Bernard (NHC Strasbourg, Université de Strasbourg (Strasbourg, França)) ;
Arrigoni, Eugenio (Ospedale Guglielmo da Saliceto (Piacenza, Itàlia)) ;
Bravi, Elena (Ospedale Guglielmo da Saliceto (Piacenza, Itàlia)) ;
Migliorini, Paola (Azienda Ospedaliera Universitaria Pisana (Pisa, Itàlia)) ;
Mathieu, Alessandro (University Clinic and AOU of Cagliari (Cagliari, Itàlia)) ;
Piga, Matteo (University Clinic and AOU of Cagliari (Cagliari, Itàlia)) ;
Drott, Ulrich (Johann Wolfgang Goethe Universität) ;
Delbrueck, Christiane (Johann Wolfgang Goethe Universität) ;
Bauhammer, Jutta (ACURA Centre for Rheumatic Diseases (Baden-Baden, Alemanya)) ;
Cagnotto, Giovanni (Skåne University Hospital (Suècia)) ;
Vancheri, Carlo (AOU Catania (Catania, Itàlia)) ;
Sambataro, Gianluca (AOU Catania (Catania, Itàlia) ;
De Langhe, Ellen (University Hospitals Leuven (Bèlgica)) ;
Sainaghi, Pier Paolo (DiMet, University of Eastern Piedmont (UPO) (Novara, Itàlia)) ;
Monti, Cristina (University of Pavia (Pavia, Itàlia)) ;
Gigli Berzolari, Francesca (University of Pavia (Pavia, Itàlia)) ;
Romano, Mariaeva (Niguarda Hospital (Milà, Itàlia)) ;
Bonella, Francesco (University Hospital Essen (Alemanya)) ;
Specker, Christof (Ruhrlandklinik, University of Duisburg-Essen (Essen, Alemanya)) ;
Schwarting, Andreas (Johannes Gutenberg-University (Mainz, Alemanya)) ;
Villa Blanco, Ignacio (Sierrallana Hospital (Torrelavega, Espanya)) ;
Selmi, Carlo (Humanitas Research Hospital (Itàlia)) ;
Ceribelli, Angela (Humanitas Research Hospital (Itàlia)) ;
Nuno, Laura (Hospital Universitario La Paz (Madrid)) ;
Mera-Varela, Antonio (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ;
Perez Gomez, Nair (Hospital Clínico Universitario (Santiago de Compostela, Galícia)) ;
Fusaro, Enrico (Città della Salute e della Scienza (Turin, Itàlia)) ;
Parisi, Simone (Città della Salute e della Scienza (Turin, Itàlia)) ;
Sinigaglia, Luigi (Hospital G. Pini-CTO (Milà, Itàlia)) ;
Del Papa, Nicoletta (Hospital G. Pini-CTO (Milà, Itàlia)) ;
Benucci, Maurizio (Azienda Ospedaliera San Giovanni di Dio (Firenze, Itàlia)) ;
Cimmino, Marco Amedeo (University of Genova (Itàlia)) ;
Riccieri, Valeria (University La Sapienza and Policlinico Umberto I (Roma, Itàlia)) ;
Conti, Fabrizio (University La Sapienza and Policlinico Umberto I (Roma, Itàlia)) ;
Sebastiani, Gian Domenico (Ospedale San Camillo (Roma, Itàlia))) ;
Iuliano, Annamaria (Ospedale San Camillo (Roma, Itàlia)) ;
Emmi, Giacomo (AOU Careggi (Firenze, Itàlia)) ;
Cammelli, Daniele (AOU Careggi (Firenze, Itàlia)) ;
Sebastiani, Marco (Azienda Ospedaliera Universitaria di Modena (Itàlia)) ;
Manfredi, Andreina (Azienda Ospedaliera Universitaria di Modena (Itàlia)) ;
Bachiller-Corral, Javier (Hospital Universitario Ramón y Cajal (Madrid)) ;
Sifuentes Giraldo, Walter Alberto (Hospital Universitario Ramón y Cajal (Madrid)) ;
Paolazzi, Giuseppe (Department of Rheumatology, Ospedale Santa Chiara, 38122 Trento, Italy) ;
Saketkoo, Lesley Ann (University Medical Center New Orleans (New Orleans, USA)) ;
Giorgi, Roberto (ASL CN 1 (Cuneo, Itàlia)) ;
Salaffi, Fausto (Polytechnic University of Marche (Jesi, Itàlia)) ;
Cifrián, José Manuel (Instituto de Investigación Sanitaria Valdecilla (Santander, Cantàbria)) ;
Caporali, Roberto (University of Milan and Gaetano Pini Hospital (Milà, Itàlia)) ;
Locatelli, Francesco (University and IRCCS Policlinico S. Matteo Foundation of Pavia (Itàlia)) ;
Marchioni, Enrico (Department of Neurology, IRCCS Mondino Foundation (Pavia, Itàlia)) ;
Pesci, Alberto (Ospedale San Gerardo (Itàlia)) ;
Dei, Giulia (Ospedale San Gerardo (Itàlia)) ;
Pozzi, Maria Rosa (Ospedale San Gerardo (Itàlia)) ;
Claudia, Lomater (Mauriziano Hospital (Turin, Itàlia)) ;
Distler, Jorg (Friedrich-Alexander-Universität Erlangen-Nürnberg (Erlangen, Alemanya)) ;
Knitza, Johannes (Friedrich-Alexander-Universität Erlangen-Nürnberg (Erlangen, Alemanya)) ;
Schett, George (Friedrich-Alexander-Universität Erlangen-Nürnberg (Erlangen, Alemanya)) ;
Iannone, Florenzo (University of Bari (Itàlia)) ;
Fornaro, Marco (University of Bari (Itàlia)) ;
Franceschini, Franco (University and ASST Spedali Civili (Brescia, Itàlia)) ;
Quartuccio, Luca (University of Udine (Itàlia)) ;
Gerli, Roberto (University of Perugia (Itàlia)) ;
Bartoloni, Elena (University of Perugia (Itàlia)) ;
Bellando Randone, Silvia (AOU Careggi (Firenze, Itàlia)) ;
Zampogna, Giuseppe (AO Brunico (Bruneck, Itàlia)) ;
Gonzalez Perez, Montserrat I. (Instituto Nacional de Enfermedades Respiratorias, Ismael Cosio Villegas, Mexico City (Mèxic)) ;
Mejia, Mayra (Instituto Nacional de Enfermedades Respiratorias, Ismael Cosio Villegas, 14080 Mexico City (Mèxic)) ;
Vicente, Esther (Instituto de Investigación Hospital Universitario de la Princesa) ;
Triantafyllias, Konstantinos (ACURA Center for Rheumatic Diseases (Bad Kreuznach, Alemanya)) ;
Lopez-Mejias, Raquel (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ;
Matucci-Cerinic, Marco (AOU Careggi (Firenze, Itàlia)) ;
Selva-O'Callaghan, Albert (Hospital Universitari Vall d'Hebron) ;
Castañeda, Santos (Universidad Autónoma de Madrid) ;
Montecucco, Carlomaurizio (University and IRCCS Policlinico S. Matteo Foundation of Pavia (Itàlia)) ;
Gonzalez-Gay, MA (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ;
Universitat Autònoma de Barcelona
Antisynthetase syndrome (ASSD) is a rare clinical condition that is characterized by the occurrence of a classic clinical triad, encompassing myositis, arthritis, and interstitial lung disease (ILD), along with specific autoantibodies that are addressed to different aminoacyl tRNA synthetases (ARS). [...]
2019 - 10.3390/jcm8112013
Journal of clinical medicine, Vol. 8 (november 2019)
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