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Cytomegalovirus retinitis: Difference between revisions - Wikipedia

Cytomegalovirus retinitis: Difference between revisions

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==Signs and symptoms==
[[File:PMID20029144 06 cytomegalovirus retinitis - pizza pie.png|thumb|The typical "pizza pie" appearance of the fundus in CMV retinitis<ref name="JAMA">{{cite journal | vauthors = To K, Friedman AH | title = Cytomegalovirus retinitis | journal = JAMA | issn = 0098-7484 | volume = 262 | issue = 23 | pages = 3337 | date = December 1989 | pmid = 2555576 | doi = 10.1001/jama.1989.03430230122038 | url = https://jamanetwork.com/journals/jama/article-abstract/379907 | url-access = subscription }}</ref><ref>{{cite journal | vauthors = Sudharshan S, Ganesh SK, Biswas J | title = Current approach in the diagnosis and management of posterior uveitis | journal = Indian Journal of Ophthalmology | issn = 0301-4738 | volume = 58 | issue = 1 | pages = 29–43 | date = January 2010 | pmid = 20029144 | pmc = 2841371 | doi = 10.4103/0301-4738.58470 | url = https://journals.lww.com/ijo/Fulltext/2010/58010/Current_approach_in_the_diagnosis_and_management.5.aspx | archive-url = https://archive.ph/iDUaj | archive-date = 6 March 2023 }}</ref><ref>{{cite magazine|magazine=EyeNet Magazine - [[American Academy of Ophthalmology]]|title=HIV-Related CMV Retinitis in the Developing World|url=https://www.aao.org/Assets/6b1e694e-62d6-4fa3-9691-dc7a2f7cb9dc/635559897697170000/february-2014-clinical-update-international-pdf|archive-url=https://web.archive.org/web/20230307073536/https://www.aao.org/Assets/6b1e694e-62d6-4fa3-9691-dc7a2f7cb9dc/635559897697170000/february-2014-clinical-update-international-pdf|archive-date=2023-03-07|format=PDF|archive-format=PDF| vauthors = Weiner G |pages=27–29|date=February 2014}}</ref><ref name="emed"/>]]
The symptoms of cytomegalovirus retinitis have it usually starting in one eye (and also have the possibility of retinal detachment), presenting as:<ref name=nih/>
* [[Blurred vision]]
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Those areas infected by cytomegalovirus have cells evolve to [[necrosis]], though inflammation within the retina is not great.
Rhegmatogenous retinal detachments can occur following the development of holes in areas of healed retinitis (retina may be [[atrophic]]).<ref>{{Cite web | vauthors = Wu L, Pakalnis VA | veditors = Law SK, Charles S, Dahl AA |url=http://emedicine.medscape.com/article/1224737-clinical#b5|title=Rhegmatogenous Retinal Detachment Clinical Presentation: History, Physical, Causes| work = Medscape |access-date=2016-03-16}}</ref><ref>{{cite journal | vauthors = Cheeran MC, Lokensgard JR, Schleiss MR | title = Neuropathogenesis of congenital cytomegalovirus infection: disease mechanisms and prospects for intervention | journal = Clinical Microbiology Reviews | issn = 0893-8512 | volume = 22 | issue = 1 | pages = 99–126, Table of Contents | date = January 2009 | pmid = 19136436 | pmc = 2620634 | doi = 10.1128/CMR.00023-08 }}</ref> [[Proliferative vitreoretinopathy]] has been observed in cases of retinal detachment.<ref>{{cite journal | vauthors = Sadaka A, Giuliari GP | title = Proliferative vitreoretinopathy: current and emerging treatments | journal = Clinical Ophthalmology | issn = 1177-5467 | volume = 6 | pages = 1325–1333 | date = January 2012 | pmid = 22942638 | pmc = 3429288 | doi = 10.2147/OPTH.S27896 }}</ref>
 
==Diagnosis==
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== Further reading ==
{{refbegin}}
* {{cite journal | vauthors = Ljungman P, Griffiths P, Paya C | title = Definitions of cytomegalovirus infection and disease in transplant recipients | journal = Clinical Infectious Diseases | issn = 1058-4838 | volume = 34 | issue = 8 | pages = 1094–1097 | date = April 2002 | pmid = 11914998 | doi = 10.1086/339329 | doi-access = free }}
* {{cite journal | vauthors = Heiden D, Ford N, Wilson D, Rodriguez WR, Margolis T, Janssens B, Bedelu M, Tun N, Goemaere E, Saranchuk P, Sabapathy K, Smithuis F, Luyirika E, Drew WL | display-authors = 6 | title = Cytomegalovirus retinitis: the neglected disease of the AIDS pandemic | journal = PLOS Medicine | issn = 1549-1676 | volume = 4 | issue = 12 | pages = e334 | date = December 2007 | pmid = 18052600 | pmc = 2100142 | doi = 10.1371/journal.pmed.0040334 }} {{open access}}
* {{cite journal | vauthors = Campbell RJ, Chow B, Victor G, Kravcik S, Hodge WG | title = Treatment of CMV retinitis with intravitral ganciclovir in the HAART era | journal = The Canadian Journal of Infectious Diseases = Journal Canadien des Maladies Infectieuses | issn = 1180-2332 | volume = 12 | issue = 5 | pages = 300–304 | date = September 2001 | pmid = 18159353 | pmc = 2094829 | doi = 10.1155/2001/851845 | doi-access = free }}
{{refend}}