| campaignbox = {{Campaignbox Roman–Persian Wars}} {{Campaignbox Crisis of the Third Century}}
}}
The '''Battle of Misiche''' ([[Koine Greek|Greek]]: {{lang|grc|Μισιχή}}), '''Mesiche''' ({{lang|grc|Μεσιχή}}), or '''Massice''' ({{lang-pal|𐭬𐭱{{lrm}}𐭩{{lrm}}𐭪{{lrm}}{{lrm}}{{lrm}}{{lrm}}}} mšyk; {{lang-xpr|𐭌{{lrm}}𐭔{{lrm}}𐭉{{lrm}}𐭊{{lrm}}}} mšyk) (dated between January 13 and March 14, 244 <span style="font-size: 10px;">AD.</span><ref name=Potter/>) was fought between the [[Sasanian Empire|Sasanians]] and the [[Roman Empire|Romans]] in Misiche, [[Mesopotamia]].<ref>{{cite journal| url = https://www.cambridge.org/core/journals/bulletin-of-the-school-of-oriental-and-african-studies/article/ad-bsoas-xiv-512-n-6/B054DC5C6581EAFB7F2F663F8E15FBDE| title = Βεσήχανα πόλις: ad BSOAS., XIV, 512, n. 6 {{!}} Bulletin of the School of Oriental and African Studies {{!}} Cambridge Core| journal = Bulletin of the School of Oriental and African Studies| date = June 1953| volume = 15| issue = 2| pages = 392–393| doi = 10.1017/S0041977X00111176| last1 = Henning| first1 = W. B.| s2cid = 183942874}} </ref>
