Ōtsu is the capital city of Shiga Prefecture, Japan
Ōtsu may also refer to:
- Ōtsu Station, a railway station in Ōtsu, Shiga, Japan
- Ōtsu District, Yamaguchi, a former district in Yamaguchi Prefecture, Japan
- Ōtsu (surname), a Japanese surname
- Ōtsu-juku, a station of the Nakasendō and the Tōkaidō
- Otsu, a variant of the Type 89 I-Go medium tank
This disambiguation page lists articles associated with the title Ōtsu.
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