Cyprodenate: Difference between revisions

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{{Short description|Chemical compound}}
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<!--Chemical data-->
<!--Chemical data-->
| C=13 | H=25 | N=1 | O=2
| C=13 | H=25 | N=1 | O=2
⚫
| smiles = CN(C)CCOC(=O)CCC1CCCCC1
| molecular_weight = 227.34
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| smiles = O=C(OCCN(C)C)CCC1CCCCC1
| InChI = 1/C13H25NO2/c1-14(2)10-11-16-13(15)9-8-12-6-4-3-5-7-12/h12H,3-11H2,1-2H3
| InChIKey = MPOYJPINNSIHAK-UHFFFAOYAN
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C13H25NO2/c1-14(2)10-11-16-13(15)9-8-12-6-4-3-5-7-12/h12H,3-11H2,1-2H3
| StdInChI = 1S/C13H25NO2/c1-14(2)10-11-16-13(15)9-8-12-6-4-3-5-7-12/h12H,3-11H2,1-2H3
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'''Cyprodenate''' ('''Actebral''') is a [[stimulant]] drug.<ref>{{vcite journal |author=Dormard Y, Levron JC, Le Fur JM |title=Pharmacokinetic study of maleate acid of 2-(N,N-dimethylaminoethanol-14C1)-cyclohexylpropionate (cyprodenate) and of N,N-dimethylaminoethanol-14C1 in animals |journal=Arzneimittelforschung |date=1975 Feb |volume=25 |issue=2 |pages=201–7 |pmid=1173033 }}</ref> It was used for counteracting the effects of [[benzodiazepine]] tranquillizer drugs before the development of newer [[antidotes]] such as [[flumazenil]].<ref>{{vcite journal |author=Bobkov Yu.G., Morozov I.S. |title=Correction of psychodepressive effects of benzodiazepine tranquilizers by administration of psychoenergizers |language=English |journal=Bulletin of Experimental Biology and Medicine |date=1982 Oct |volume=94 |issue=4 |pages=1366-1369 |doi=10.1007/BF00827201 }}</ref> It produces [[dimethylethanolamine]] as a [[metabolite]], and so might be expected to produce [[nootropic]] effects.
'''Cyprodenate''' ('''Actebral''') is a [[stimulant]] drug.<ref>{{cite journal | vauthors = Dormard Y, Levron JC, Le Fur JM | title = Pharmacokinetic study of maleate acid of 2-(N,N-dimethylaminoethanol-14C1)-cyclohexylpropionate (cyprodenate) and of N,N-dimethylaminoethanol-14C1 in animals | journal = Arzneimittel-Forschung | volume = 25 | issue = 2 | pages = 201–7 | date = February 1975 | pmid = 1173033 }}</ref> It was used for counteracting the effects of [[benzodiazepine]] tranquillizer drugs before the development of newer [[antidotes]] such as [[flumazenil]].<ref>{{cite journal | vauthors = Bobkov I, Morozov IS | title = [Correction of psychodepressive effects of benzodiazepine tranquilizers by administration of psychostimulants] | language = English | journal = Biulleten' Eksperimental'noi Biologii I Meditsiny | volume = 94 | issue = 10 | pages = 48–51 | date = October 1982 | pmid = 6129008 | doi = 10.1007/BF00827201 | s2cid = 19153614 }}</ref> It produces [[dimethylethanolamine]] as a [[metabolite]].{{citation needed|date=September 2018}}


== See also ==
== See also ==
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{{Stimulants}}
{{Stimulants}}
{{Nootropics}}
{{Psychostimulants, agents used for ADHD and nootropics}}
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{{Cholinergics}}


{{Acetylcholine receptor modulators}}
{{Monoamine releasing agents}}

⚫
[[Category:Cholinergics]]
[[Category:Nootropics]]
[[Category:Nootropics]]
[[Category:Stimulants]]
[[Category:Stimulants]]
[[Category:Propionates]]
[[Category:Propionate esters]]
[[Category:Amines]]
[[Category:Dimethylamino compounds]]
[[Category:Prodrugs]]
[[Category:Prodrugs]]
[[Category:Cyclohexyl compounds]]




Latest revision as of 07:57, 25 March 2024

Cyprodenate
Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
  • 2-dimethylaminoethyl 3-cyclohexylpropanoate
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.036.025 Edit this at Wikidata
Chemical and physical data
FormulaC13H25NO2
Molar mass227.348 g·mol−1
3D model (JSmol)
  • CN(C)CCOC(=O)CCC1CCCCC1
  • InChI=1S/C13H25NO2/c1-14(2)10-11-16-13(15)9-8-12-6-4-3-5-7-12/h12H,3-11H2,1-2H3 checkY
  • Key:MPOYJPINNSIHAK-UHFFFAOYSA-N checkY
  (verify)

Cyprodenate (Actebral) is a stimulant drug.[1] It was used for counteracting the effects of benzodiazepine tranquillizer drugs before the development of newer antidotes such as flumazenil.[2] It produces dimethylethanolamine as a metabolite.[citation needed]

See also[edit]

References[edit]

  1. ^ Dormard Y, Levron JC, Le Fur JM (February 1975). "Pharmacokinetic study of maleate acid of 2-(N,N-dimethylaminoethanol-14C1)-cyclohexylpropionate (cyprodenate) and of N,N-dimethylaminoethanol-14C1 in animals". Arzneimittel-Forschung. 25 (2): 201–7. PMID 1173033.
  2. ^ Bobkov I, Morozov IS (October 1982). "[Correction of psychodepressive effects of benzodiazepine tranquilizers by administration of psychostimulants]". Biulleten' Eksperimental'noi Biologii I Meditsiny. 94 (10): 48–51. doi:10.1007/BF00827201. PMID 6129008. S2CID 19153614.


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