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Chondroitin: Difference between revisions

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{{Cleanup rewrite|date=March 2024}}
#REDIRECT [[Chondroitin sulfate]]
{{Short description|Chemical derivative of chondrin}}
A '''chondroitin''' is a [[chondrin]] derivative.<ref>{{MeshName|Chondroitin}}</ref>

Types include:
* [[Chondroitin sulfate]]
* [[Dermatan sulfate]]

Chondroitin as a supplement is now commonly used (often in combination with [[glucosamine]]) in treating the joint disease of [[osteoarthritis]].<ref name=":0">{{Cite journal|last1=Vasiliadis|first1=Haris S|last2=Tsikopoulos|first2=Konstantinos|date=2017|title=Glucosamine and chondroitin for the treatment of osteoarthritis|journal=World Journal of Orthopedics|language=en|volume=8|issue=1|pages=1–11|doi=10.5312/wjo.v8.i1.1|issn=2218-5836|pmc=5241539|pmid=28144573 |doi-access=free }}</ref> In contrast to the symptomatic treatments, chondroitin can modify the progression of a disease process in the patient which it can be used as an alternative medicine.<ref name=":0" /> Chondroitin's effect toward the articular cartilage integrity as it is part of the [[proteoglycan]] molecules.<ref name=":1">{{Cite journal|last=Tavakol|first=Kamran|title=Glucosamine and Chondroitin for Treatment of Osteoarthritis: A Systematic Quality Assessment and Meta-analysis|journal=Physical Therapy|volume=80|issue=10|page=1049}}</ref> The cartilage proteoglycan synthesis can speed up as chondroitin is going through the pathway of the alimentary canal.<ref name=":1" /> Research has been conducted to show the effectiveness of chondroitin and results indicate that it helps to manage pain in knee and hip, slow down the progression and also recovery.<ref>{{Cite journal|last1=Zhu|first1=Xiaoyue|last2=Sang|first2=Lingli|last3=Wu|first3=Dandong|last4=Rong|first4=Jiesheng|last5=Jiang|first5=Liying|date=December 2018|title=Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials|journal=Journal of Orthopaedic Surgery and Research|language=en|volume=13|issue=1|pages=170|doi=10.1186/s13018-018-0871-5|issn=1749-799X|pmc=6035477|pmid=29980200 |doi-access=free }}</ref> However, the effectiveness of the drugs is still doubtful.<ref name=":1" />

==References==
{{reflist}}

{{Glycosaminoglycans}}

[[Category:Glycosaminoglycans]]

Latest revision as of 19:10, 27 March 2024

A chondroitin is a chondrin derivative.[1]

Types include:

Chondroitin as a supplement is now commonly used (often in combination with glucosamine) in treating the joint disease of osteoarthritis.[2] In contrast to the symptomatic treatments, chondroitin can modify the progression of a disease process in the patient which it can be used as an alternative medicine.[2] Chondroitin's effect toward the articular cartilage integrity as it is part of the proteoglycan molecules.[3] The cartilage proteoglycan synthesis can speed up as chondroitin is going through the pathway of the alimentary canal.[3] Research has been conducted to show the effectiveness of chondroitin and results indicate that it helps to manage pain in knee and hip, slow down the progression and also recovery.[4] However, the effectiveness of the drugs is still doubtful.[3]

References[edit]

  1. ^ Chondroitin at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
  2. ^ a b Vasiliadis, Haris S; Tsikopoulos, Konstantinos (2017). "Glucosamine and chondroitin for the treatment of osteoarthritis". World Journal of Orthopedics. 8 (1): 1–11. doi:10.5312/wjo.v8.i1.1. ISSN 2218-5836. PMC 5241539. PMID 28144573.
  3. ^ a b c Tavakol, Kamran. "Glucosamine and Chondroitin for Treatment of Osteoarthritis: A Systematic Quality Assessment and Meta-analysis". Physical Therapy. 80 (10): 1049.
  4. ^ Zhu, Xiaoyue; Sang, Lingli; Wu, Dandong; Rong, Jiesheng; Jiang, Liying (December 2018). "Effectiveness and safety of glucosamine and chondroitin for the treatment of osteoarthritis: a meta-analysis of randomized controlled trials". Journal of Orthopaedic Surgery and Research. 13 (1): 170. doi:10.1186/s13018-018-0871-5. ISSN 1749-799X. PMC 6035477. PMID 29980200.