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This page in a nutshell: Anti-MDA5 Dermatomyositis is a subtype of Dermatomyositis, which is chronic inflammation of the muscles and skin.

Anti-MDA5 Dermatomyositis

Anti-melanoma differentiation-associated protein 5 (MDA5) antibody-positive dermatomyositis (MDA5-DM)^[1] is a subtype of dermatomyositis (not to be confused with Dermatology). The aetiology, still unclear, however, new study suggests that viral infection is a potential trigger of MDA5-DM. Many factors, some of which, T cells, B cells, neutrophils and macrophages, are implicated in the pathophysiology of MDA5-DM. MDA5-DM is still a rare systemic autoimmune disease.

History

References

^ Lu, Xin; Peng, Qinglin; Wang, Guochun (2024-01). "Anti-MDA5 antibody-positive dermatomyositis: pathogenesis and clinical progress". Nature Reviews Rheumatology. 20 (1): 48–62. doi:10.1038/s41584-023-01054-9. ISSN 1759-4804. {{cite journal}}: Check date values in: |date= (help)

[1] Lu, Xin; Peng, Qinglin; Wang, Guochun (2024-01). "Anti-MDA5 antibody-positive dermatomyositis: pathogenesis and clinical progress". Nature Reviews Rheumatology. 20 (1): 48–62. doi:10.1038/s41584-023-01054-9. ISSN 1759-4804. {{cite journal}}: Check date values in: |date= (help)

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