POLE3: Difference between revisions

POLE3
Identifiers
Aliases	POLE3, CHARAC17, CHRAC17, YBL1, p17, polymerase (DNA) epsilon 3, accessory subunit, DNA polymerase epsilon 3, accessory subunit, CHRAC2
External IDs	OMIM: 607267; MGI: 1933378; HomoloGene: 9694; GeneCards: POLE3; OMA:POLE3 - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	113,410,675 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	62,443,305 bp
RNA expression pattern
	Top expressed in
	gonad; ; gastrocnemius muscle; ; granulocyte; ; monocyte; ; human penis; ; ganglionic eminence; ; muscle of thigh; ; rectum; ; ventricular zone; ; bone marrow;
	Top expressed in
	spermatocyte; ; ventricular zone; ; yolk sac; ; secondary oocyte; ; zygote; ; fetal liver hematopoietic progenitor cell; ; seminiferous tubule; ; morula; ; molar; ; mandibular prominence;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; DNA binding; DNA-directed DNA polymerase activity; nucleotidyltransferase activity; protein binding; protein heterodimerization activity; histone acetyltransferase activity;
Cellular component	epsilon DNA polymerase complex; nucleus; nucleoplasm;
Biological process	DNA replication; histone H3 acetylation; DNA biosynthetic process; G1/S transition of mitotic cell cycle; cellular response to DNA damage stimulus; CENP-A containing chromatin assembly; cellular response to gamma radiation; DNA replication initiation; telomere maintenance via semi-conservative replication;
	Sources:Amigo / QuickGO
Orthologs
	54107
	59001
	ENSG00000148229
	ENSMUSG00000028394
	Q9NRF9
	Q9JKP7
	NM_001278255; NM_017443
	NM_021498
	NP_001265184; NP_059139
	NP_067473
	Wikidata
View/Edit Human	View/Edit Mouse

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Revision as of 13:38, 11 June 2008

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Polymerase (DNA directed), epsilon 3 (p17 subunit), also known as POLE3, is a human gene.^[5]

Template:PBB Summary

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000148229 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000028394 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: POLE3 polymerase (DNA directed), epsilon 3 (p17 subunit)".

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 {{PBB_Further_reading
 | citations =
-*{{cite journal  | author=Andersson B, Wentland MA, Ricafrente JY, ''et al.'' |title=A "double adaptor" method for improved shotgun library construction. |journal=Anal. Biochem. |volume=236 |issue= 1 |pages= 107-13 |year= 1996 |pmid= 8619474 |doi= 10.1006/abio.1996.0138 }}
+*{{cite journal  | author=Andersson B, Wentland MA, Ricafrente JY, ''et al.'' |title=A "double adaptor" method for improved shotgun library construction. |journal=Anal. Biochem. |volume=236 |issue= 1 |pages= 107–13 |year= 1996 |pmid= 8619474 |doi= 10.1006/abio.1996.0138 }}
-*{{cite journal  | author=Yu W, Andersson B, Worley KC, ''et al.'' |title=Large-scale concatenation cDNA sequencing. |journal=Genome Res. |volume=7 |issue= 4 |pages= 353-8 |year= 1997 |pmid= 9110174 |doi=  }}
+*{{cite journal  | author=Yu W, Andersson B, Worley KC, ''et al.'' |title=Large-scale concatenation cDNA sequencing. |journal=Genome Res. |volume=7 |issue= 4 |pages= 353–8 |year= 1997 |pmid= 9110174 |doi=  }}
-*{{cite journal  | author=Li Y, Pursell ZF, Linn S |title=Identification and cloning of two histone fold motif-containing subunits of HeLa DNA polymerase epsilon. |journal=J. Biol. Chem. |volume=275 |issue= 30 |pages= 23247-52 |year= 2000 |pmid= 10801849 |doi= 10.1074/jbc.M002548200 }}
+*{{cite journal  | author=Li Y, Pursell ZF, Linn S |title=Identification and cloning of two histone fold motif-containing subunits of HeLa DNA polymerase epsilon. |journal=J. Biol. Chem. |volume=275 |issue= 30 |pages= 23247–52 |year= 2000 |pmid= 10801849 |doi= 10.1074/jbc.M002548200 }}
-*{{cite journal  | author=Poot RA, Dellaire G, Hülsmann BB, ''et al.'' |title=HuCHRAC, a human ISWI chromatin remodelling complex contains hACF1 and two novel histone-fold proteins. |journal=EMBO J. |volume=19 |issue= 13 |pages= 3377-87 |year= 2000 |pmid= 10880450 |doi= 10.1093/emboj/19.13.3377 }}
+*{{cite journal  | author=Poot RA, Dellaire G, Hülsmann BB, ''et al.'' |title=HuCHRAC, a human ISWI chromatin remodelling complex contains hACF1 and two novel histone-fold proteins. |journal=EMBO J. |volume=19 |issue= 13 |pages= 3377–87 |year= 2000 |pmid= 10880450 |doi= 10.1093/emboj/19.13.3377 }}
-*{{cite journal  | author=Bolognese F, Imbriano C, Caretti G, Mantovani R |title=Cloning and characterization of the histone-fold proteins YBL1 and YCL1. |journal=Nucleic Acids Res. |volume=28 |issue= 19 |pages= 3830-8 |year= 2000 |pmid= 11000277 |doi=  }}
+*{{cite journal  | author=Bolognese F, Imbriano C, Caretti G, Mantovani R |title=Cloning and characterization of the histone-fold proteins YBL1 and YCL1. |journal=Nucleic Acids Res. |volume=28 |issue= 19 |pages= 3830–8 |year= 2000 |pmid= 11000277 |doi=  }}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
+*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
-*{{cite journal  | author=Post SM, Tomkinson AE, Lee EY |title=The human checkpoint Rad protein Rad17 is chromatin-associated throughout the cell cycle, localizes to DNA replication sites, and interacts with DNA polymerase epsilon. |journal=Nucleic Acids Res. |volume=31 |issue= 19 |pages= 5568-75 |year= 2003 |pmid= 14500819 |doi=  }}
+*{{cite journal  | author=Post SM, Tomkinson AE, Lee EY |title=The human checkpoint Rad protein Rad17 is chromatin-associated throughout the cell cycle, localizes to DNA replication sites, and interacts with DNA polymerase epsilon. |journal=Nucleic Acids Res. |volume=31 |issue= 19 |pages= 5568–75 |year= 2003 |pmid= 14500819 |doi=  }}
-*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40-5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
+*{{cite journal  | author=Ota T, Suzuki Y, Nishikawa T, ''et al.'' |title=Complete sequencing and characterization of 21,243 full-length human cDNAs. |journal=Nat. Genet. |volume=36 |issue= 1 |pages= 40–5 |year= 2004 |pmid= 14702039 |doi= 10.1038/ng1285 }}
-*{{cite journal  | author=Humphray SJ, Oliver K, Hunt AR, ''et al.'' |title=DNA sequence and analysis of human chromosome 9. |journal=Nature |volume=429 |issue= 6990 |pages= 369-74 |year= 2004 |pmid= 15164053 |doi= 10.1038/nature02465 }}
+*{{cite journal  | author=Humphray SJ, Oliver K, Hunt AR, ''et al.'' |title=DNA sequence and analysis of human chromosome 9. |journal=Nature |volume=429 |issue= 6990 |pages= 369–74 |year= 2004 |pmid= 15164053 |doi= 10.1038/nature02465 }}
-*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
+*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
-*{{cite journal  | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173-8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
+*{{cite journal  | author=Rual JF, Venkatesan K, Hao T, ''et al.'' |title=Towards a proteome-scale map of the human protein-protein interaction network. |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 }}
-*{{cite journal  | author=Olsen JV, Blagoev B, Gnad F, ''et al.'' |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635-48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 }}
+*{{cite journal  | author=Olsen JV, Blagoev B, Gnad F, ''et al.'' |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 }}
 }}
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Revision as of 13:38, 11 June 2008

References

Further reading