Dibutylchloromethyltin chloride: Difference between revisions
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'''Dibutylchloromethyltin chloride''' ('''DBCT''') is a toxic [[organotin compound]]. It's a potent and irreversible [[ATP synthase]] inhibitor.<ref name="bc">{{cite journal |last1=Cain |first1=K |last2=Partis |first2=MD |last3=Griffiths |first3=DE |title=Dibutylchloromethyltin chloride, a covalent inhibitor of the adenosine triphosphate synthase complex. |journal=The Biochemical |
'''Dibutylchloromethyltin chloride''' ('''DBCT''') is a toxic [[organotin compound]]. It's a potent and irreversible [[ATP synthase]] inhibitor.<ref name="bc">{{cite journal |last1=Cain |first1=K |last2=Partis |first2=MD |last3=Griffiths |first3=DE |title=Dibutylchloromethyltin chloride, a covalent inhibitor of the adenosine triphosphate synthase complex. |journal=The Biochemical Journal |date=15 September 1977 |volume=166 |issue=3 |pages=593–602 |pmid=145860 |pmc=1165045|doi=10.1042/bj1660593 }}</ref><ref>{{cite journal |last1=Moore |first1=Anthony L. |last2=Linnett |first2=Paul E. |last3=Beechey |first3=R. Brian |title=Dibutylchloromethyltin chloride, a potent inhibitor of electron transport in plant mitochondria |journal=Journal of Bioenergetics and Biomembranes |date=August 1980 |volume=12 |issue=3–4 |pages=309–323 |doi=10.1007/bf00744691}}</ref><ref>{{cite journal |last1=Diwan |first1=Joyce Johnson |title=Some effects of dibutylchloromethyltin chloride and other reagents on mitochondrial K+ flux |journal=Journal of Bioenergetics and Biomembranes |date=February 1982 |volume=14 |issue=1 |pages=15–22 |doi=10.1007/bf00744076|pmid=7142136 }}</ref> DBCT is a volatile liquid with powerful [[vesicant]] effects.<ref name="bc"></ref> |
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==See also== |
==See also== |
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Revision as of 15:56, 14 February 2019
| Names | |
|---|---|
| IUPAC name
Dibutyl(chloro)(chloromethyl)stannane
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| Other names
DBCT
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| Identifiers | |
3D model (JSmol)
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| ChemSpider | |
PubChem CID
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CompTox Dashboard (EPA)
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| Properties | |
| C9H20Cl2Sn | |
| Molar mass | 317.87 g·mol−1 |
| Hazards | |
| Occupational safety and health (OHS/OSH): | |
Main hazards
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Toxic, vesicant |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Dibutylchloromethyltin chloride (DBCT) is a toxic organotin compound. It's a potent and irreversible ATP synthase inhibitor.[1][2][3] DBCT is a volatile liquid with powerful vesicant effects.[1]
See also
References
- ^ a b Cain, K; Partis, MD; Griffiths, DE (15 September 1977). "Dibutylchloromethyltin chloride, a covalent inhibitor of the adenosine triphosphate synthase complex". The Biochemical Journal. 166 (3): 593–602. doi:10.1042/bj1660593. PMC 1165045. PMID 145860.
- ^ Moore, Anthony L.; Linnett, Paul E.; Beechey, R. Brian (August 1980). "Dibutylchloromethyltin chloride, a potent inhibitor of electron transport in plant mitochondria". Journal of Bioenergetics and Biomembranes. 12 (3–4): 309–323. doi:10.1007/bf00744691.
- ^ Diwan, Joyce Johnson (February 1982). "Some effects of dibutylchloromethyltin chloride and other reagents on mitochondrial K+ flux". Journal of Bioenergetics and Biomembranes. 14 (1): 15–22. doi:10.1007/bf00744076. PMID 7142136.
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