Galanolactone
Appearance
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Preferred IUPAC name
(3E)-3-{2-[(1R,2S,4aS,8aS)-5,5,8a-Trimethyloctahydro-1H-spiro[naphthalene-2,2′-oxiran]-1-yl]ethylidene}oxolan-2-one | |
Identifiers | |
3D model (JSmol)
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ChemSpider | |
MeSH | galanolactone |
PubChem CID
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UNII | |
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Properties | |
C20H30O3 | |
Molar mass | 318.45 g/mol |
Solubility in acetone | Soluble |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Galanolactone is a diterpenoid lactone first isolated from ginger. It is present in acetone extracts of ginger, and appears to be an antagonist at 5-HT3 receptors.[1]
References
[edit]- ^ Huang, Q.; Iwamoto, Y.; Aoki, S.; Tanaka, N.; Tajima, K.; Yamahara, J.; Takaishi, Y.; Yoshida, M.; Tomimatsu, T.; Tamai, Y. (1991). "Anti-5-hydroxytryptamine3 effect of galanolactone, diterpenoid isolated from ginger". Chemical & Pharmaceutical Bulletin. 39 (2): 397–399. doi:10.1248/cpb.39.397. PMID 2054863.