As international students are joining online classes at U.S. based universities, the need for virtual instructors to have an understanding of techniques and strategies to assist these students in succeeding in the virtual classroom is essential. This article reflects upon students from Japan, Venezuela, and Egypt and the particular challenges they might face in a virtual classroom environment based on Hofstede's Cross Country Tool comparisons. Due to collectivist views, attitudes toward uncertainty avoidance, power distance attitudes, and differing expectations, instructors may need to consider providing explicit instructions and detailed grading details. International students may need additional guidance in discussions and collaborative group project assignments. Best practices for use with internationals students will conform to general best practices in teaching. However, a more proactive approach with international students by the instructor will avoid potential issues.