Aaron Ciechanover (miyos wonten ing Haifa wonten ing taun 1947) inggih punika salah satunggaling ilmuwan Israèl. Ciechanover inggih punika profesor wonten ing Pérangan Biokimia lan Direktur Lembaga Penelitian Ilmu Kedhokteran Kulawarga Rappaport wonten ing Technion (Institut Teknologi Israèl) ing Haifa, Israèl. Piyambakipun dados guru besar wonten ing Technion nalika taun 1992, lan minangka profesor kolega ing mrika wiwit taun 1987 dumugi ing taun 1992.^[1]

Ciechanover nyandhang gelar Ph.D lan dhokter. Piyambakipun sinau kadhokteran wonten ing Fakultas Kedhokteran Universitas Ibrani wonten ing wewengkon Yerusalem, pikantuk gelar dhokter nalika taun 1974. Antawis taun 1974-1977, Ciechanover gadhah tugas wonten ing Angkatan Pertahanan Israèl. Antawis taun 1977-1981, Ciechanover inggih punika minangka salah satunggaling mahasiswa sarjana kaliyan Avram Hershko wonten ing Technion.^[2] Ciechanover pikantuk gelar Doctor of Philosophy nalika taun 1981. Antawis taun 1982-1984, Ciechanover minangka salah satunggaling anggota pascadhoktoral wonten ing Pérangan Biologi, Institut Teknologi Massachusetts, ing pundi piyambakipun sinau babagan lasialoglikoprotein lan reseptor transfer wonten ing laboratorium Harvey Lodish, lan ugi "berkolaborasi" kaliyan Varshavsky lan mahasiswanipun, Finley, wonten ing studinipun wonten ing sel tikus ts85.^[3]

Karya mandiri Ciechanover kawiwitan taun 1986, wonten ing Pérangan Biokimia, Technion, Israèl.

Pakurmatan lan penghargaan

1996-sapunika: Anggota Dewan Organisasi Biologi Molekuler Éropa
1997: Penghargaan Henry Taube (Technion, Israèl) kanggé kaunggulan wonten ing riset
1999: Penghargaan Wachter, déning Universitas Innsbruck, Ostenrik (kaliyan A. Hershko)
2004: Penghargaan Nobel babagan Kimia ^[4]

Publikasi paling relevan

Ciechanover, A., Hod, Y., lan Hershko, A. (1978) A heat-stable polypeptide component of an ATP-dependent proteolytic system from reticulocytes. Biochem. Biophys. Res. Commun. 81, 1100-1105.
Hershko, A., Ciechanover, A., Heller, H., Haas, A. L., lan Rose, I. A. (1980) Proposed role of ATP in protéin breakdown: conjugation of proteins with multiple chains of the polypeptide of ATP - dependent proteolysis. Proc. Natl. Acad. Sci. USA 77, 1783-1786.
Ciechanover, A., Elias, S., Heller, H. lan Hershko, A. (1982) Covalent affinity purification of I ubiquitin-activating enzyme. J. Biol. Chem. 257, 2537-2542.
Hershko, A., Heller, H., Elias, S. lan Ciechanover, A. (1983) Components of ubiquitin-protéin ligase system: resolution, affinity purification, and role in protéin breakdown. J. Biol. Chem. 258, 8206-8214.
Finley, D., Ciechanover, A. lan Varshavsky, A. (1984) Thermolability of ubiquitin-activating enzyme from the mammalian cell cycle mutant ts85. Cell 37, 43-55.
Ciechanover, A., Finley, D. lan Varshavsky, A. (1984) Ubiquitin dependence of selective protéin degradation demonstrated in the mammalian cell cycle mutant ts85. Cell 37 ,57-66.
Ferber, S. lan Ciechanover, A. (1987) Role of Arginine-tRNA in Protein Degradation by the Ubiquitin Pathway. Nature 326,808-811.
Ciechanover, A., Ferber, S., Ganoth, D., Elias, S., Hershko, A. lan Arfin, S. (1988) Purification and characterization of arginyl-tRNA-protéin transferase from rabbit reticulocytes: its involvement in modification and ubiquitin-dependent degradation of proteins bearing acidic N-termini. J. Biol. Chem. 263, 11155-11167.

Catheta Suku=

Aaron Ciechanover
Aaron Ciechanover
	Ciechanover in 2014
Lair	1 Oktober 1947; Haifa, British Mandate of Palestine
Bangsa	Israèl
Kondhang ing	ubiquitin-mediated protéin degradation
Bebungah	Bebungah Nobel dalam Kimia (2004)
	Karièr ngèlmiah
Babagan	Biology

Pranala njaba

Yayasan Albert dan Mary Lasker Archived 2006-10-03 at the Wayback Machine.

[1] ttp://www.nobelprize.org/nobel_prizes/chemistry/laureates/2004/ciechanover-autobio.html

[2] ttp://www.nobelprize.org/nobel_prizes/chemistry/laureates/2004/ciechanover-lecture.html

[3] ttp://www.jewishvirtuallibrary.org/jsource/biography/Ciechanover.html

[4] ttp://www.nndb.com/people/051/000140628/

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