A team from the Wistar Institute has demonstrated the role of Parkin—a protein implicated in Parkinson's disease—in the body's innate immune response to cancer. Parkin is not expressed in several cancers.
Sep 18, 2024
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The c-Met-directed antibody-drug conjugate telisotuzumab vedotin demonstrated durable responses and an acceptable safety profile in patients of Asian race with c-Met protein-overexpressing, epidermal growth factor receptor ...
Sep 10, 2024
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A Ludwig Cancer Research study has discovered that recurrent tumors of the aggressive brain cancer glioblastoma multiforme (GBM) grow out of the fibrous scars of malignant predecessors destroyed by interventions such as radiotherapy, ...
Sep 9, 2024
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In a study published in Cell Chemical Biology, a research team led by Prof. Tan Weihong and Prof. Wu Qin from the Hangzhou Institute of Medical of the Chinese Academy of Sciences has identified protein arginine methyltransferases ...
Sep 6, 2024
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A common skin fungus, Malassezia globosa may invade deep tissues through the skin or by other means, then cause tumor growth, according to a new study. The study results were reported in mBio.
Sep 5, 2024
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A team of scientists led by Dr. Björn von Eyss has discovered an additional control mechanism that prevents the growth of liver cancer.
Aug 29, 2024
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Oregon Health & Science University researchers have identified a combination of treatments that show promise in slowing the progression of cancer and reducing tumor growth. Their research lays the groundwork for developing ...
Aug 27, 2024
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A new study led by researchers at Beth Israel Deaconess Medical Center (BIDMC) and Boston Children's Hospital and published in Nature Immunology shows how tumors grow by avoiding the immune system.
Aug 26, 2024
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A new report describes a promising approach to studying neurofibromatosis type 1 (NF1), a genetic condition with limited treatment options. The condition causes a number of different cancerous and non-cancerous tumors to ...
Aug 22, 2024
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The growth of healthy tissues in the body depends on the development of new blood vessels, a process called angiogenesis, that enables proper blood flow, meaning nutrients and oxygen are delivered while toxic metabolic products ...
Aug 22, 2024
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Transforming growth factor (sometimes referred to as Tumor growth factor, or TGF) is used to describe two classes of polypeptide growth factors, TGF
The name "Transforming Growth Factor" is somewhat arbitrary, since the two classes of TGFs are not structurally or genetically related to one another, and they act through different receptor mechanisms. Furthermore, they do not always induce cellular transformation, and are not the only growth factors that induce cellular transformation.
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