(Translated by https://www.hiragana.jp/)
The spectrum of eosinophilic cystitis in males: case series and literature review

The spectrum of eosinophilic cystitis in males: case series and literature review

Arch Pathol Lab Med. 2009 Feb;133(2):289-94. doi: 10.5858/133.2.289.

Abstract

Context: Eosinophilic cystitis (EC) is an inflammatory condition of the bladder that has been linked to food allergens, infectious agents, drugs, and other genitourinary conditions. Like interstitial cystitis, EC has a strong female predominance. It is characterized by an intense eosinophilic infiltrate in the acute phase and fibrosis in the chronic phase.

Objectives: To document and focus on specific features of EC in males and highlight the relationship between clinical and histopathologic findings.

Design: The bladder biopsies of male patients were reviewed. Eight cases of EC were selected.

Results: Several known associations were noted as well as unreported features and associations such as Charcot-Leyden crystals, celiac disease, lupus anticoagulant, and additional viral and bacterial agents.

Conclusions: Eosinophilic cystitis represents a response to a variety of agents and may often be overlooked. The temporally biphasic morphologic features are the hallmark of this condition. Because clinical and imaging studies are not specific, a high index of clinical suspicion is often crucial to the correct diagnosis and proper management of EC.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Aged
  • Biopsy
  • Cystectomy
  • Cystitis / diagnosis*
  • Cystitis / pathology*
  • Cystitis / therapy
  • Eosinophils / pathology*
  • Glycoproteins / metabolism
  • Histamine Antagonists / therapeutic use
  • Humans
  • Infant
  • Lysophospholipase / metabolism
  • Male
  • Middle Aged
  • Urinary Bladder / metabolism
  • Urinary Bladder / pathology

Substances

  • Glycoproteins
  • Histamine Antagonists
  • Lysophospholipase
  • lysolecithin acylhydrolase