Granzymes are the essential downstream effector molecules for the control of primary virus infections by cytolytic leukocytes
A Müllbacher, P Waring, R Tha Hla… - Proceedings of the …, 1999 - National Acad Sciences
Analysis of perforin-deficient mice has identified the cytolytic pathway and perforin as the
preeminent effector molecule in T cell-mediated control of virus infections. In this paper, we …
preeminent effector molecule in T cell-mediated control of virus infections. In this paper, we …
[PDF][PDF] MOF acetyl transferase regulates transcription and respiration in mitochondria
A functional crosstalk between epigenetic regulators and metabolic control could provide a
mechanism to adapt cellular responses to environmental cues. We report that the well-known …
mechanism to adapt cellular responses to environmental cues. We report that the well-known …
Improving the friction model for the simulation of cutting processes
M Storchak, HC Möhring, T Stehle - Tribology International, 2022 - Elsevier
The here developed friction model for numerical simulations of machining processes takes
account of the physical‐mechanical phenomena occurring in different cutting zones by …
account of the physical‐mechanical phenomena occurring in different cutting zones by …
Performance of creatinine-based equations to estimate glomerular filtration rate in White and Black populations in Europe, Brazil and Africa
P Delanaye, E Vidal-Petiot, J Björk… - Nephrology Dialysis …, 2023 - academic.oup.com
Background A new Chronic Kidney Disease Epidemiology Collaboration equation without
the race variable has been recently proposed (CKD-EPI AS ). This equation has neither been …
the race variable has been recently proposed (CKD-EPI AS ). This equation has neither been …
The spectrum of kidney biopsies in hospitalized patients with COVID-19, acute kidney injury and/or proteinuria
S Ferlicot, M Jamme, F Gaillard… - Nephrology Dialysis …, 2021 - academic.oup.com
Background The coronavirus disease 2019 (COVID-19) may be associated with kidney injury,
which may impact patient's prognosis. Methods We report a multicentric retrospective case …
which may impact patient's prognosis. Methods We report a multicentric retrospective case …
Glomerular filtration rate measured based on iomeprol clearance assessed at CT urography in living kidney donor candidates
T Stehlé, F Wei, S Brabant, A Luciani, P Grimbert… - Radiology, 2023 - pubs.rsna.org
Background Estimating glomerular filtration rate (GFR) from serum creatinine can be
inaccurate, and current procedures for measuring GFR are time-consuming and cumbersome. …
inaccurate, and current procedures for measuring GFR are time-consuming and cumbersome. …
Classification of colon polyps in NBI endoscopy using vascularization features
The evolution of colon cancer starts with colon polyps. There are two different types of colon
polyps, namely hyperplasias and adenomas. Hyperplasias are benign polyps which are …
polyps, namely hyperplasias and adenomas. Hyperplasias are benign polyps which are …
Texture classification by modeling joint distributions of local patterns with Gaussian mixtures
Texture classification generally requires the analysis of patterns in local pixel neighborhoods.
Statistically, the underlying processes are comprehensively described by their joint …
Statistically, the underlying processes are comprehensively described by their joint …
Six months of hydroxyurea reduces albuminuria in patients with sickle cell disease
The earliest symptom of glomerular injury in patients with sickle cell disease (SCD) is
microalbuminuria. The effect of hydroxyurea (HU) on urine albumin-to-creatinine ratio (ACR) is …
microalbuminuria. The effect of hydroxyurea (HU) on urine albumin-to-creatinine ratio (ACR) is …
Phospholipase A2 receptor and sarcoidosis-associated membranous nephropathy
Of the glomerulonephritis associated with sarcoidosis, membranous nephropathy (MN) is
the most prevalent. Coincidence or a causal relationship between these two diseases is …
the most prevalent. Coincidence or a causal relationship between these two diseases is …