MK-212

MK-212
	2-Hloro-6-(1-piperazinil)pirazin
Drugi nazivi	CPP
Identifikacija
CAS registarski broj	64022-27-1
PubChem	107992
ChemSpider	97104
Jmol-3D slike	Slika 1
SMILES
	Clc1nc(cnc1)N2CCNCC2
InChI
	InChI=1S/C8H11ClN4/c9-7-5-11-6-8(12-7)13-3-1-10-2-4-13/h5-6,10H,1-4H2 ; Kod: CJAWPFJGFFNXQI-UHFFFAOYSA-N InChI=1/C8H11ClN4/c9-7-5-11-6-8(12-7)13-3-1-10-2-4-13/h5-6,10H,1-4H2; Kod: CJAWPFJGFFNXQI-UHFFFAOYAX
Svojstva
Molekulska formula	C8H11ClN4
Molarna masa	198.65 g mol−1
	; ; Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje (25 °C, 100 kPa) materijala
	Infobox references

MK-212 (CPP, 6-hloro-2-(l-piperazinil)pirazin)^[4] je serotoninski agonist.^[5] On promoviše sekreciju serumskog prolaktina i kortizola kod ljudi.^[6]

Reference

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
↑ Clineschidmt, BV (1979). „MK-212: A serotonin-like agonist in the CNS”. General pharmacology 10 (4): 287–90. PMID 488663.
↑ Bastani, B.; Nash, J. F.; Meltzer, H. Y. (1990). „Prolactin and Cortisol Responses to MK-212, a Serotonin Agonist, in Obsessive-Compulsive Disorder”. Archives of General Psychiatry 47 (9): 833–9. DOI:10.1001/archpsyc.1990.01810210041006. PMID 2203327.
↑ Lowy, Martin T.; Meltzer, Herbert Y. (1988). „Stimulation of serum cortisol and prolactin secretion in humans by MK-212, a centrally active serotonin agonist”. Biological Psychiatry 23 (8): 818–28. DOI:10.1016/0006-3223(88)90070-4. PMID 3365458.

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