Fas-aktivirana serin/treonin kinaza
(Preusmjereno sa stranice STK10)
Fas-aktivirana serin/treonin kinaza | |||||||||
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Identifikatori | |||||||||
EC broj | 2.7.11.8 | ||||||||
CAS broj | 170347-50-9 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Fas-aktivirana serin/treonin kinaza (EC 2.7.11.8, FAST, FASTK, STK10) je enzim sa sistematskim imenom ATP:(Fas-aktivirani serin/treonin protein) fosfotransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
Ovaj enzim se aktivira tokom Fas-posredovane apoptoze.
- ↑ Tian, Q., Taupin, J., Elledge, S., Robertson, M. and Anderson, P. (1995). „Fas-activated serine/threonine kinase (FAST) phosphorylates TIA-1 during Fas-mediated apoptosis”. J. Exp. Med. 182: 865-874. PMID 7544399.
- ↑ Li, W., Simarro, M., Kedersha, N. and Anderson, P. (2004). „FAST is a survival protein that senses mitochondrial stress and modulates TIA-1-regulated changes in protein expression”. Mol. Cell. Biol. 24: 10718-10732. PMID 15572676.
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