ARD1A
N-terminalni acetiltransferazni kompleks ARD1, homolog A je enzim koji je kod čoveka kodiran ARD1A genom.[1][2]
N(alfa)-acetiltransferaza 10, NatA katalitička podjedinica | |||||||||||
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Identifikatori | |||||||||||
Simboli | NAA10; ARD1; ARD1A; DXS707; NATD; TE2 | ||||||||||
Vanjski ID | OMIM: 300013 MGI: 1915255 HomoloGene: 2608 GeneCards: NAA10 Gene | ||||||||||
EC broj | 2.3.1.88 | ||||||||||
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Pregled RNK izražavanja | |||||||||||
podaci | |||||||||||
Ortolozi | |||||||||||
Vrsta | Čovek | Miš | |||||||||
Entrez | 8260 | 56292 | |||||||||
Ensembl | ENSG00000102030 | ENSMUSG00000031388 | |||||||||
UniProt | P41227 | Q9QY36 | |||||||||
RefSeq (mRNA) | NM_001256119 | NM_001177965 | |||||||||
RefSeq (protein) | NP_001243048 | NP_001171436 | |||||||||
Lokacija (UCSC) |
Chr HG1497_PATCH: 153.14 - 153.14 Mb |
Chr X: 73.92 - 73.92 Mb | |||||||||
PubMed pretraga | [1] | [2] |
Reference
уреди- ^ Tribioli C, Mancini M, Plassart E, Bione S, Rivella S, Sala C, Torri G, Toniolo D (1995). „Isolation of new genes in distal Xq28: transcriptional map and identification of a human homologue of the ARD1 N-acetyl transferase of Saccharomyces cerevisiae”. Hum Mol Genet. 3 (7): 1061—7. PMID 7981673. doi:10.1093/hmg/3.7.1061.
- ^ „Entrez Gene: ARD1A ARD1 homolog A, N-acetyltransferase (S. cerevisiae)”.
Literatura
уреди- Brenner V, Nyakatura G, Rosenthal A, Platzer M (1997). „Genomic organization of two novel genes on human Xq28: compact head to head arrangement of IDH gamma and TRAP delta is conserved in rat and mouse.”. Genomics. 44 (1): 8—14. PMID 9286695. doi:10.1006/geno.1997.4822.
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- Jeong JW; Bae MK; Ahn MY; et al. (2003). „Regulation and destabilization of HIF-1alpha by ARD1-mediated acetylation.”. Cell. 111 (5): 709—20. PMID 12464182. doi:10.1016/S0092-8674(02)01085-1.
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- Bilton R; Mazure N; Trottier E; et al. (2005). „Arrest-defective-1 protein, an acetyltransferase, does not alter stability of hypoxia-inducible factor (HIF)-1alpha and is not induced by hypoxia or HIF.”. J. Biol. Chem. 280 (35): 31132—40. PMID 15994306. doi:10.1074/jbc.M504482200.
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- Arnesen T; Gromyko D; Horvli O; et al. (2006). „Expression of N-acetyl transferase human and human Arrest defective 1 proteins in thyroid neoplasms.”. Thyroid. 15 (10): 1131—6. PMID 16279846. doi:10.1089/thy.2005.15.1131.
- Arnesen T; Kong X; Evjenth R; et al. (2006). „Interaction between HIF-1 alpha (ODD) and hARD1 does not induce acetylation and destabilization of HIF-1 alpha.”. FEBS Lett. 579 (28): 6428—32. PMID 16288748. doi:10.1016/j.febslet.2005.10.036.
- Kim SH; Park JA; Kim JH; et al. (2006). „Characterization of ARD1 variants in mammalian cells.”. Biochem. Biophys. Res. Commun. 340 (2): 422—7. PMID 16376303. doi:10.1016/j.bbrc.2005.12.018.
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- Arnesen T; Gromyko D; Pendino F; et al. (2006). „Induction of apoptosis in human cells by RNAi-mediated knockdown of hARD1 and NATH, components of the protein N-alpha-acetyltransferase complex.”. Oncogene. 25 (31): 4350—60. PMID 16518407. doi:10.1038/sj.onc.1209469.
- Beausoleil SA; Villén J; Gerber SA; et al. (2006). „A probability-based approach for high-throughput protein phosphorylation analysis and site localization.”. Nat. Biotechnol. 24 (10): 1285—92. PMID 16964243. doi:10.1038/nbt1240.
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