UDP-N-acetilmuramoil-L-alanil-D-glutamat-L-lizinska ligaza
| UDP-N-acetilmuramoil-L-alanil-D-glutamat-L-lizinska ligaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 6.3.2.7 | ||||||||
| CAS broj | 9023-51-2 | ||||||||
| Baze podataka | |||||||||
| IntEnz | IntEnz pregled | ||||||||
| BRENDA | BRENDA pristup | ||||||||
| ExPASy | NiceZyme pregled | ||||||||
| KEGG | KEGG pristup | ||||||||
| MetaCyc | metabolički put | ||||||||
| PRIAM | profil | ||||||||
| Strukture PBP | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
UDP-N-acetilmuramoil-L-alanil-D-glutamat-L-lizinska ligaza (EC 6.3.2.7, MurE sintetaza, UDP-N-acetilmuramoil-L-alanil-D-glutamil-L-lizin sintetaza, uridin difosfo-N-acetilmuramoilalanil-D-glutamillizin sintetaza, UPD-MurNAc-L-Ala-D-Glu:L-Lys ligaza) je enzim sa sistematskim imenom UDP-N-acetilmuramoil-L-alanil-D-glutamat:L-lizin gama-ligaza (formira ADP).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- ATP + UDP-N-acetilmuramoil-L-alanil-D-glutamat + L-lizin ADP + fosfat + UDP-N-acetilmuramoil-L-alanil-D-glutamil-L-lizin
Ovaj enzim učestvuje u sintezi peptida ćelijskog zida.
Reference
[уреди | уреди извор]- ^ Ito, E. & Strominger, J.L. (1962). „Enzymatic synthesis of the peptide in bacterial uridine nucleotides. I. Enzymatic addition of L-alanine, D-glutamic acid, and L-lysine”. J. Biol. Chem. 237: 2689—2695.
- ^ van Heijenoort, J. (2001). „Recent advances in the formation of the bacterial peptidoglycan monomer unit”. Nat. Prod. Rep. 18: 503—519. PMID 11699883.
Literatura
[уреди | уреди извор]- Nicholas C. Price; Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third изд.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 изд.). Wiley-Interscience. ISBN 0471205036.
- Branden C; Tooze J. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 изд.). Wiley Classics Library. ISBN 0471303097.
Spoljašnje veze
[уреди | уреди извор]- UDP-N-acetylmuramoyl-L-alanyl-D-glutamate---L-lysine+ligase на US National Library of Medicine Medical Subject Headings (MeSH)
