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|---|---|
| Accession Number: | P12236 |
| Protein Name: | ADP/ATP translocase 3 |
| Length: | 298 |
| Molecular Weight: | 32866.00 |
| Species: | Homo sapiens (Human) [9606] |
| Number of TMSs: | 6 |
| Location1 / Topology2 / Orientation3: | Mitochondrion inner membrane1 / Multi-pass membrane protein2 |
| Substrate | adenine |
Cross database links:
| Entrez Gene ID: | 293 |
|---|---|
| Pfam: | PF00153 |
| KEGG: | hsa:293 hsa:293 |
Gene Ontology
GO:0016021
C:integral to membrane
GO:0005744
C:mitochondrial inner membrane presequence translocase complex
GO:0005471
F:ATP:ADP antiporter activity
GO:0005488
F:binding
GO:0046732
P:active induction of host immune response by virus
GO:0006915
P:apoptotic process
GO:0006112
P:energy reserve metabolic process
GO:0050796
P:regulation of insulin secretion
GO:0044281
P:small molecule metabolic process
GO:0019058
P:viral infectious cycle
GO:0044267
P:cellular protein metabolic process
GO:0006626
P:protein targeting to mitochondrion
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References (20)[1] “DNA sequences of two expressed nuclear genes for human mitochondrial ADP/ATP translocase.” Cozens A.L.et.al. 2541251 [2] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 [3] “Two distinct genes for ADP/ATP translocase are expressed at the mRNA level in adult human liver.” Houldsworth J.et.al. 2829183 [4] “Study of PTPC composition during apoptosis for identification of viral protein target.” Verrier F.et.al. 15033708 [5] “Mitochondrial membrane permeabilization by HIV-1 Vpr.” Deniaud A.et.al. 16120388 [6] “Influenza virus PB1-F2 protein induces cell death through mitochondrial ANT3 and VDAC1.” Zamarin D.et.al. 16201016 [7] “Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer.” Rikova K.et.al. 18083107 [8] “Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle.” Daub H.et.al. 18691976 [9] “Lysine acetylation targets protein complexes and co-regulates major cellular functions.” Choudhary C.et.al. 19608861 [10] “Initial characterization of the human central proteome.” Burkard T.R.et.al. 21269460 [11] “DNA sequences of two expressed nuclear genes for human mitochondrial ADP/ATP translocase.” Cozens A.L.et.al. 2541251 [12] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 [13] “Two distinct genes for ADP/ATP translocase are expressed at the mRNA level in adult human liver.” Houldsworth J.et.al. 2829183 [14] “Study of PTPC composition during apoptosis for identification of viral protein target.” Verrier F.et.al. 15033708 [15] “Mitochondrial membrane permeabilization by HIV-1 Vpr.” Deniaud A.et.al. 16120388 [16] “Influenza virus PB1-F2 protein induces cell death through mitochondrial ANT3 and VDAC1.” Zamarin D.et.al. 16201016 | |
External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MTEQAISFAK DFLAGGIAAA ISKTAVAPIE RVKLLLQVQH ASKQIAADKQ YKGIVDCIVR 61: IPKEQGVLSF WRGNLANVIR YFPTQALNFA FKDKYKQIFL GGVDKHTQFW RYFAGNLASG 121: GAAGATSLCF VYPLDFARTR LAADVGKSGT EREFRGLGDC LVKITKSDGI RGLYQGFSVS 181: VQGIIIYRAA YFGVYDTAKG MLPDPKNTHI VVSWMIAQTV TAVAGVVSYP FDTVRRRMMM 241: QSGRKGADIM YTGTVDCWRK IFRDEGGKAF FKGAWSNVLR GMGGAFVLVL YDELKKVI