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|---|---|
| Accession Number: | Q06143 |
| Protein Name: | DIC1 aka L8300.2 aka YLR348C |
| Length: | 298 |
| Molecular Weight: | 32992.00 |
| Species: | Saccharomyces cerevisiae (Baker's yeast) [4932] |
| Number of TMSs: | 6 |
| Location1 / Topology2 / Orientation3: | Mitochondrion inner membrane1 / Multi-pass membrane protein2 |
| Substrate | phosphate(3-), sulfate, sulfurous acid, oxaloacetate(2-), malate(2-), succinate(2-) |
Cross database links:
| DIP: | DIP-8816N |
|---|---|
| RefSeq: | NP_013452.1 |
| Entrez Gene ID: | 851063 |
| Pfam: | PF00153 |
| KEGG: | sce:YLR348C |
Gene Ontology
GO:0016021
C:integral to membrane
GO:0005743
C:mitochondrial inner membrane
GO:0015297
F:antiporter activity
GO:0005488
F:binding
GO:0005310
F:dicarboxylic acid transmembrane transporter...
GO:0006835
P:dicarboxylic acid transport
GO:0006817
P:phosphate transport
GO:0055085
P:transmembrane transport
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References (10)[1] “Identification of a novel gene encoding the yeast mitochondrial dicarboxylate transport protein via overexpression, purification, and characterization of its protein product.” Kakhniashvili D.et.al. 9020177 [2] “The nucleotide sequence of Saccharomyces cerevisiae chromosome XII.” Johnston M.et.al. 9169871 [3] “Characterization, purification and properties of the yeast mitochondrial dicarboxylate carrier (Saccharomyces cerevisiae).” Lancar-Benba J.et.al. 8831951 [4] “Bacterial overexpression of putative yeast mitochondrial transport proteins.” Mayor J.A.et.al. 9559855 [5] “The mitochondrial dicarboxylate carrier is essential for the growth of Saccharomyces cerevisiae on ethanol or acetate as the sole carbon source.” Palmieri L.et.al. 10027973 [6] “Biogenesis of the dicarboxylate carrier (DIC): translocation across the mitochondrial outer membrane and subsequent release from the TOM channel are membrane potential-independent.” Zara V.et.al. 11502005 | |
External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MSTNAKESAG KNIKYPWWYG GAAGIFATMV THPLDLAKVR LQAAPMPKPT LFRMLESILA 61: NEGVVGLYSG LSAAVLRQCT YTTVRFGAYD LLKENVIPRE QLTNMAYLLP CSMFSGAIGG 121: LAGNFADVVN IRMQNDSALE AAKRRNYKNA IDGVYKIYRY EGGLKTLFTG WKPNMVRGIL 181: MTASQVVTYD VFKNYLVTKL DFDASKNYTH LTASLLAGLV ATTVCSPADV MKTRIMNGSG 241: DHQPALKILA DAVRKEGPSF MFRGWLPSFT RLGPFTMLIF FAIEQLKKHR VGMPKEDK