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Biotechnology / Life Sciences in Baden-Württemberg Archive 2006
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11.01.2009

Archive 2006



Article 1 - 20 from 238


Dr. Dorothea Siegel-Axel is working on a new therapy for the treatment of atherosclerotic high-risk patients. She has developed a method for the cultivation of cells from human arterial walls.

The Landesstiftung Baden-Württemberg foundation intends to fund fundamental, internationally competitive research in the field of biocompatible biomaterials. A new funding programme, which was commenced in December of 2006, addresses universities, university hospitals, universities of applied sciences and non-profit extramural research institutions in Baden-Württemberg.

Can a look through the microscope provide information about whether individual cancer cells are passing through the human body that cannot be detected with traditional methods? The dream of the early detection of life-threatening diseases such as cancer might become reality in the not too distant future.

Natural killer cells | 18.12.2006
In their fight against cancer, 45 international scientists came together at the International Science Forum of the University of Heidelberg (IWH) held on 6 – 9 December 2006. Dr. Carsten Watzl, from the Department of General Immunology at the Medical Faculty in Heidelberg, organised the symposium and united theoretical scientists and clinicians who have already successfully used natural killer cells in the therapy of cancer. The participants hoped to gain new insights and directions in modern cancer therapy. Dr. Carsten Watzl was conferred the Klaus-Georg and Sigrid Hengstberger Prize 2006 for organising this important meeting.

The loss of muscle mass in intensive care patients suffering from sepsis is not the consequence of long periods of lying in bed. It has been shown that this is an independent muscle disease that is caused, amongst other things, by an excessive inflammatory reaction. The physiologist Oliver Friedrich from Heidelberg was awarded a research scholarship by the German Sepsis Society, honouring his achievements on the pathomechanism of such muscle weakness.

Despite the incompatibility of the blood groups and the production of antibodies against the donor tissue (positive cross match), a 18-year patient was given a new kidney at the University Hospital in Tübingen. Living kidney donations are now possible despite blood group and tissue incompatibility.

The Federal Ministry of Education and Research will fund the thematic priority "Micro-Nano-Integration for Microsystems Technology (MNI-mst)" within the scope of the "Microsystems in the Innovation Area System Integration" programme.

Over the next four years, the Federal Ministry of Education and Research (BMBF) will focus on application-oriented bionics projects with a total of €20 million in the scope of the "BIONA – Bionic innovations for sustainable products and technologies". Deadline for submitting proposals is 28 February 2007.

Prof. Irmgard Sinning’s research group at the Biochemistry Centre of the University Heidelberg has clarified the molecular machinery used by bacteria to synthesise pyridoxal 5’-phosphate (PLP), the biologically active form of vitamin B6.

On 24th November, the University of Constance was home to two events relating to nanotechnology: The new nanotechnology laboratory of the physics and chemistry departments was officially opened and the new “Nano Award” was announced by the Universitätsgesellschaft Konstanz e.V. (UGK).

The field of bioinformatics at the University of Freiburg is strong and extremely diverse. Apart from the Department of Bioinformatics, which is part of the Institute of Computer Science, the Faculty of Biology has a Chair for Experimental Bioinformatics and a Chair for Bioinformatics and Molecular Genetics. Although the term bioinformatics is not actually used in many other research groups, this discipline still plays a key role in their research activities. For example, plant biotechnologists, neuroscientists and scientists working in systems biology use bioformatics as an essential tool in their simulations and models.

After six years developing COPASI, the research groups led by Dr. Ursula Kummer at EML Research gGmbH, Heidelberg, and Professor Pedro Mendes at the Virginia Bioinformatics Institute, have provided the scientific community with an effective software package for the simulation and analysis of complex biochemical pathways. COPASI is a software package aimed at bioinformaticians and experimental researchers who use the software to calculate the function of biochemical reaction networks and adapt their model systems to the data gained in the laboratory.

Maize, rice or corn: Researchers assume there is a vast and inexhaustible potential in wild varieties and old country breeds. KWS SAAT AG and the University of Hohenheim created an endowed chair to study just this issue.

Biologist Dr. Corinna Hermann presented the current state of knowledge and her own research priorities in a talk entitled “Live and die with bacteria – mechanisms of bacterial persistence”.

Dr. Vedat Schwenger, assistant medical director of the Medical Hospital of the University of Heidelberg, was awarded the Nils Alwall Prize 2006 of the German Society of Nephrology. The prize comes with 10,000 Euro in prize money and is awarded every year for groundbreaking research in the field of kidney replacement therapy. The prize is named after the Swedish nephrologist Nils Alwall, who is the father of extracorporeal blood treatment.

In the leading scientific journal Science Prof. Dr. Bernd Fakler’s research group at the Physiological Institute at the University of Freiburg reported on the discovery of a molecular super complex from a calcium and potassium channel, which the brain’s neurones use to control their electrical activity and the release of hormones. This discovery unlocks one of the oldest secrets in neurobiology – how can potassium channels be controlled by way of calcium ions without leading to neurone damage?

From April 11th 2006, the Fridericiana University of Karlsruhe and the Karlsruhe Research Centre (FZK) have decided to pool their expertise under one roof. From April, both partners have continued their joint research activities - greatly expanded over the past decades - at the Karlsruhe Institute for Technology (KIT). Researchers are working closely together with the common goal being an even closer collaboration in research programmes, teaching and working together with industry. The Federal Minister of Research and Education Annette Schavan sees this cooperation as a completely new type of collaboration between the University and non-university research institutions, something that is totally new in German science.

Merging the world of informatics with the world of biology is Prof. Dr. Rolf Backofen’s ultimate goal. The computer scientist is the Chair for bioinformatics at the University of Freiburg. The main focus of his research lies in studying and predicting RNA as well as protein structure motifs.

Whilst having lunch in the cafeteria a scientist is talking with his colleagues about his project. Another scientist overhears the conversation and remembers another person in the building who is looking into similar issues. In the end, this accidental meeting brings together two people who would otherwise never have met. A software project undertaken by Professor Michael Berthold and GATC Biotech hopes to turn such accidental encounters into a reliable strategy.

Dr. Wolfgang Wohlleben, Professor of Microbiology and Biotechnology at the University of Tübingen, is particularly interested in the biology of antibiotic synthesis. Bacterial pathogens can build up resistance over time, making the development of newer and more effective medicines necessary. One source of such antibiotics is actinomycetes. These soil bacteria synthesize these active substances presumably because antibiotics afford them some nutritional advantage in their habitat. But what bacteria can do beyond pure survival is something the Tübingen researcher would like to know because this may result in new natural compounds for all aspects of everyday life.



Article 1 - 20 from 238

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