Eugene Wesley Ely, M.D.

1215 21st Ave. South
Med Center East 6109
Nashville, TN 37232-8300

Dr. E. Wesley Ely is a professor of medicine at Vanderbilt University School of Medicine with subspecialty training in Pulmonary and Critical Care Medicine. Dr. Ely’s research has focused on improving the care and outcomes of critically ill patients with ICU-acquired brain disease (manifested acutely as delirium and chronically as long-term cognitive impairment). He has built the ICU Delirium and Cognitive Impairment Study Group, amassing several thousand patients into cohort studies and randomized trials that were used to build the methodology for ICU acquired brain disease research. His team developed the primary tool (CAM-ICU, translated into 25+ languages) by which delirium and health-related quality of life outcomes are measured in ICU-based trials and clinically at the bedside in ICUs worldwide. Dr. Ely has been continuously federally funded (NIA and/or VA) for 14 years. He has over 250 peer-reviewed publications and over 50 published book chapters and editorials.

Dr. Ely is a subspecialist in Pulmonary and Critical Care Medicine who conducts patient-oriented, health services research as a Professor of Medicine in the Division of Allergy, Pulmonary, and Critical Care Medicine at Vanderbilt University School of Medicine. He is also a practicing intensivist with a focus on Geriatric ICU Care, as the Associate Director for Research for the VA Tennessee Valley Geriatric Research and Education Clinical Center.

Dr. E. Wesley Ely, MD, MPH is a professor of medicine at Vanderbilt University School of Medicine with subspecialty training in Pulmonary and Critical Care Medicine and a particular passion for care of older critically ill patients.

Sepsis, ARDS, Outcomes in the ICU, Aging, Mechanical Ventilation, Weaning, End-of-Life

Bond SM, Dietrich MS, Gilbert J, Ely EW, Jackson JC, Murphy BA. Neurocognitive function in patients with head and neck cancer undergoing primary or adjuvant chemoradiation treatment. Support Care Cancer [print-electronic]. 2016 Oct; 24(10): 4433-42. PMID: 27225527, PII: 10.1007/s00520-016-3284-1, DOI: 10.1007/s00520-016-3284-1, ISSN: 1433-7339.

Hughes CG, Pandharipande PP, Thompson JL, Chandrasekhar R, Ware LB, Ely EW, Girard TD. Endothelial Activation and Blood-Brain Barrier Injury as Risk Factors for Delirium in Critically Ill Patients. Crit. Care Med. 2016 Sep; 44(9): e809-17. PMID: 27088157, PMCID: PMC4987204, DOI: 10.1097/CCM.0000000000001739, ISSN: 1530-0293.

Smith HA, Han JH, Ely EW. Meeting the Challenges of Delirium Assessment Across the Aging Spectrum. Crit. Care Med. 2016 Sep; 44(9): 1775-7. PMID: 27525996, PMCID: PMC4988335, PII: 00003246-201609000-00018, DOI: 10.1097/CCM.0000000000001966, ISSN: 1530-0293.

Ely EW. Swimming pool in the ICU [editorial]. Intensive Care Med [print-electronic]. 2016 Sep; 42(9): 1502-3. PMID: 27515156, PII: 10.1007/s00134-016-4434-0, DOI: 10.1007/s00134-016-4434-0, ISSN: 1432-1238.

Kleinpell R, Vasilevskis EE, Fogg L, Ely EW. Exploring the association of hospice care on patient experience and outcomes of care. BMJ Support Palliat Care [print-electronic]. 2016 Aug 8/16/2016; PMID: 27531840, PII: bmjspcare-2015-001001, DOI: 10.1136/bmjspcare-2015-001001, ISSN: 2045-4368.

Goligher EC, Del Sorbo L, Cheung AM, Alibhai SM, Liao L, Easson A, Halpern J, Ely EW, Sulmasy DP, Hwang SW. Why conscientious objection merits respect [letter]. CMAJ. 2016 Aug 8/9/2016; 188(11): 822-3. PMID: 27503992, PMCID: PMC4978582, PII: 188/11/822-a, DOI: 10.1503/cmaj.1150113, ISSN: 1488-2329.

Hughes CG, Patel MB, Jackson JC, Girard TD, Geevarghese SK, Norman BC, Thompson JL, Chandrasekhar R, Brummel NE, May AK, Elstad MR, Wasserstein ML, Goodman RB, Moons KG, Dittus RS, Ely EW, Pandharipande PP, . Surgery and Anesthesia Exposure Is Not a Risk Factor for Cognitive Impairment After Major Noncardiac Surgery and Critical Illness. Ann. Surg [print-electronic]. 2016 Jul 7/18/2016; PMID: 27433893, DOI: 10.1097/SLA.0000000000001885, ISSN: 1528-1140.

Colantuoni E, Dinglas VD, Ely EW, Hopkins RO, Needham DM. Statistical methods for evaluating delirium in the ICU. Lancet Respir Med [print-electronic]. 2016 Jul; 4(7): 534-6. PMID: 27264776, PII: S2213-2600(16)30138-2, DOI: 10.1016/S2213-2600(16)30138-2, ISSN: 2213-2619.

Pollock JS, Hollenbeck RD, Wang L, Holmes B, Young MN, Peters M, Ely EW, McPherson JA, Vasilevskis EE. Delirium in Survivors of Cardiac Arrest Treated With Mild Therapeutic Hypothermia. Am. J. Crit. Care. 2016 Jul; 25(4): e81-9. PMID: 27369041, PII: 25/4/e81, DOI: 10.4037/ajcc2016581, ISSN: 1937-710X.

Rice KL, Bennett MJ, Berger L, Jennings B, Eckhardt L, Fabré-LaCoste N, Houghton D, Vidal G, Gropen T, Diggs E, Barry E, St John J, Mathew S, Egger A, Ryan S, Egger R, Galarneau D, Gaines K, Ely EW. A Pilot Randomized Controlled Trial of the Feasibility of a Multicomponent Delirium Prevention Intervention Versus Usual Care in Acute Stroke. J Cardiovasc Nurs [print-electronic]. 2016 Jun 6/15/2016; PMID: 27306854, DOI: 10.1097/JCN.0000000000000356, ISSN: 1550-5049.

Han JH, Wilson A, Graves AJ, Shintani A, Schnelle JF, Ely EW. A quick and easy delirium assessment for nonphysician research personnel. Am J Emerg Med [print-electronic]. 2016 Jun; 34(6): 1031-6. PMID: 27021131, PMCID: PMC4899095, PII: S0735-6757(16)00176-5, DOI: 10.1016/j.ajem.2016.02.069, ISSN: 1532-8171.

Zimmerman JJ, Watson RS, Ely EW. Daily sedation interruption in children warrants further study [letter]. Intensive Care Med [print-electronic]. 2016 Jun; 42(6): 1101-2. PMID: 27033884, PII: 10.1007/s00134-016-4290-y, DOI: 10.1007/s00134-016-4290-y, ISSN: 1432-1238.

Vasilevskis EE, Ely EW, Girard TD. The authors reply. Crit. Care Med. 2016 Jun; 44(6): e451-2. PMID: 27182878, PII: 00003246-201606000-00066, DOI: 10.1097/CCM.0000000000001748, ISSN: 1530-0293.

Norman BC, Jackson JC, Graves JA, Girard TD, Pandharipande PP, Brummel NE, Wang L, Thompson JL, Chandrasekhar R, Ely EW. Employment Outcomes After Critical Illness: An Analysis of the Bringing to Light the Risk Factors and Incidence of Neuropsychological Dysfunction in ICU Survivors Cohort. Crit. Care Med [print-electronic]. 2016 May 5/11/2016; PMID: 27171492, DOI: 10.1097/CCM.0000000000001849, ISSN: 1530-0293.

Dinglas VD, Hopkins RO, Wozniak AW, Hough CL, Morris PE, Jackson JC, Mendez-Tellez PA, Bienvenu OJ, Ely EW, Colantuoni E, Needham DM. One-year outcomes of rosuvastatin versus placebo in sepsis-associated acute respiratory distress syndrome: prospective follow-up of SAILS randomised trial. Thorax [print-electronic]. 2016 May; 71(5): 401-10. PMID: 26936876, PII: thoraxjnl-2015-208017, DOI: 10.1136/thoraxjnl-2015-208017, ISSN: 1468-3296.

Chan KS, Aronson Friedman L, Dinglas VD, Hough CL, Morris PE, Mendez-Tellez PA, Jackson JC, Ely EW, Hopkins RO, Needham DM. Evaluating Physical Outcomes in Acute Respiratory Distress Syndrome Survivors: Validity, Responsiveness, and Minimal Important Difference of 4-Meter Gait Speed Test. Crit. Care Med. 2016 May; 44(5): 859-68. PMID: 26963329, DOI: 10.1097/CCM.0000000000001760, ISSN: 1530-0293.

Ely EW, Pandharipande PP. The Evolving Approach to Brain Dysfunction in Critically Ill Patients [editorial]. JAMA. 2016 Apr 4/12/2016; 315(14): 1455-6. PMID: 26976552, PII: 2503417, DOI: 10.1001/jama.2016.2708, ISSN: 1538-3598.

Smith HA, Gangopadhyay M, Goben CM, Jacobowski NL, Chestnut MH, Savage S, Rutherford MT, Denton D, Thompson JL, Chandrasekhar R, Acton M, Newman J, Noori HP, Terrell MK, Williams SR, Griffith K, Cooper TJ, Ely EW, Fuchs DC, Pandharipande PP. The Preschool Confusion Assessment Method for the ICU: Valid and Reliable Delirium Monitoring for Critically Ill Infants and Children. Crit. Care Med. 2016 Mar; 44(3): 592-600. PMID: 26565631, PMCID: PMC4764386, DOI: 10.1097/CCM.0000000000001428, ISSN: 1530-0293.

Balas MC, Devlin JW, Verceles AC, Morris P, Ely EW. Adapting the ABCDEF Bundle to Meet the Needs of Patients Requiring Prolonged Mechanical Ventilation in the Long-Term Acute Care Hospital Setting: Historical Perspectives and Practical Implications. Semin Respir Crit Care Med [print-electronic]. 2016 Feb; 37(1): 119-35. PMID: 26820279, DOI: 10.1055/s-0035-1570361, ISSN: 1098-9048.

Needham DM, Colantuoni E, Dinglas VD, Hough CL, Wozniak AW, Jackson JC, Morris PE, Mendez-Tellez PA, Ely EW, Hopkins RO. Rosuvastatin versus placebo for delirium in intensive care and subsequent cognitive impairment in patients with sepsis-associated acute respiratory distress syndrome: an ancillary study to a randomised controlled trial. Lancet Respir Med [print-electronic]. 2016 Jan 1/28/2016; PMID: 26832963, PII: S2213-2600(16)00005-9, DOI: 10.1016/S2213-2600(16)00005-9, ISSN: 2213-2619.

Girard TD, Dittus RS, Ely EW. Critical Illness Brain Injury. Annu. Rev. Med. 2016 Jan 1/14/2016; 67: 497-513. PMID: 26768245, DOI: 10.1146/annurev-med-050913-015722, ISSN: 1545-326X.

Patel MB, Jackson JC, Morandi A, Girard TD, Hughes CG, Thompson JL, Kiehl AL, Elstad MR, Wasserstein ML, Goodman RB, Beckham JC, Chandrasekhar R, Dittus RS, Ely EW, Pandharipande PP. Incidence and Risk Factors for ICU-related Posttraumatic Stress Disorder In Veterans and Civilians. Am. J. Respir. Crit. Care Med [print-electronic]. 2016 Jan 1/6/2016; PMID: 26735627, DOI: 10.1164/rccm.201506-1158OC, ISSN: 1535-4970.

Hatch LD, Grubb PH, Lea AS, Walsh WF, Markham MH, Whitney GM, Slaughter JC, Stark AR, Ely EW. Endotracheal Intubation in Neonates: A Prospective Study of Adverse Safety Events in 162 Infants. J. Pediatr [print-electronic]. 2016 Jan; 168: 62-66.e6. PMID: 26541424, PMCID: PMC4698044, PII: S0022-3476(15)01151-8, DOI: 10.1016/j.jpeds.2015.09.077, ISSN: 1097-6833.

Choi L, Ferrell BA, Vasilevskis EE, Pandharipande PP, Heltsley R, Ely EW, Stein CM, Girard TD. Population Pharmacokinetics of Fentanyl in the Critically Ill. Crit. Care Med. 2016 Jan; 44(1): 64-72. PMID: 26491862, PMCID: PMC4755937, DOI: 10.1097/CCM.0000000000001347, ISSN: 1530-0293.

Vasilevskis EE, Pandharipande PP, Graves AJ, Shintani A, Tsuruta R, Ely EW, Girard TD. Validity of a Modified Sequential Organ Failure Assessment Score Using the Richmond Agitation-Sedation Scale. Crit. Care Med. 2016 Jan; 44(1): 138-46. PMID: 26457749, PMCID: PMC4748963, DOI: 10.1097/CCM.0000000000001375, ISSN: 1530-0293.

Hughes CG, Brummel NE, Girard TD, Graves AJ, Ely EW, Pandharipande PP. Change in endothelial vascular reactivity and acute brain dysfunction during critical illness [letter]. Br J Anaesth. 2015 Nov; 115(5): 794-5. PMID: 26475809, PMCID: PMC4608489, PII: aev332, DOI: 10.1093/bja/aev332, ISSN: 1471-6771.

Card E, Pandharipande P, Tomes C, Lee C, Wood J, Nelson D, Graves A, Shintani A, Ely EW, Hughes C. Emergence from general anaesthesia and evolution of delirium signs in the post-anaesthesia care unit. Br J Anaesth [print-electronic]. 2015 Sep; 115(3): 411-7. PMID: 25540068, PMCID: PMC4533730, PII: aeu442, DOI: 10.1093/bja/aeu442, ISSN: 1471-6771.

Serafim RB, Bozza FA, Soares M, do Brasil PE, Tura BR, Ely EW, Salluh JI. Pharmacologic prevention and treatment of delirium in intensive care patients: A systematic review. J Crit Care [print-electronic]. 2015 Aug; 30(4): 799-807. PMID: 25957498, PII: S0883-9441(15)00150-1, DOI: 10.1016/j.jcrc.2015.04.005, ISSN: 1557-8615.

Stollings JL, Foss JJ, Ely EW, Ambrose AM, Rice TW, Girard TD, Wheeler AP. Pharmacist leadership in ICU quality improvement: coordinating spontaneous awakening and breathing trials. Ann Pharmacother [print-electronic]. 2015 Aug; 49(8): 883-91. PMID: 25907528, PII: 1060028015582050, DOI: 10.1177/1060028015582050, ISSN: 1542-6270.

Han JH, Vasilevskis EE, Schnelle JF, Shintani A, Dittus RS, Wilson A, Ely EW. The Diagnostic Performance of the Richmond Agitation Sedation Scale for Detecting Delirium in Older Emergency Department Patients. Acad Emerg Med [print-electronic]. 2015 Jul; 22(7): 878-82. PMID: 26113020, PMCID: PMC4516221, DOI: 10.1111/acem.12706, ISSN: 1553-2712.

Yevchak AM, Han JH, Doherty K, Archambault EG, Kelly B, Chandrasekhar R, Ely EW, Rudolph JL. Impaired Arousal in Older Adults Is Associated With Prolonged Hospital Stay and Discharge to Skilled Nursing Facility. J Am Med Dir Assoc [print-electronic]. 2015 Jul 7/1/2015; 16(7): 586-9. PMID: 25744874, PMCID: PMC4668713, PII: S1525-8610(15)00100-0, DOI: 10.1016/j.jamda.2015.01.093, ISSN: 1538-9375.

Koga Y, Tsuruta R, Murata H, Matsuo K, Ito T, Ely EW, Shintani A, Wakamatsu H, Sanui M, Yamase H. Reliability and validity assessment of the Japanese version of the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU). Intensive Crit Care Nurs [print-electronic]. 2015 Jun; 31(3): 165-70. PMID: 25468294, PII: S0964-3397(14)00089-5, DOI: 10.1016/j.iccn.2014.10.002, ISSN: 1532-4036.

Jackson JC, Morandi A, Girard TD, Merkle K, Graves AJ, Thompson JL, Shintani AK, Gunther ML, Cannistraci CJ, Rogers BP, Gore JC, Warrington HJ, Ely EW, Hopkins RO, . Functional brain imaging in survivors of critical illness: A prospective feasibility study and exploration of the association between delirium and brain activation patterns. J Crit Care [print-electronic]. 2015 Jun; 30(3): 653.e1-7. PMID: 25769901, PMCID: PMC4489139, PII: S0883-9441(15)00050-7, DOI: 10.1016/j.jcrc.2015.01.017, ISSN: 1557-8615.

Brummel NE, Balas MC, Morandi A, Ferrante LE, Gill TM, Ely EW. Understanding and reducing disability in older adults following critical illness. Crit. Care Med. 2015 Jun; 43(6): 1265-75. PMID: 25756418, PMCID: PMC4640688, DOI: 10.1097/CCM.0000000000000924, ISSN: 1530-0293.

Ely EW. Embracing the spiritual history. Linacre Q. 2015 May; 82(2): 112-5. PMID: 25999608, PMCID: PMC4434795, PII: lnq-82-112, DOI: 10.1179/0024363915Z.000000000118, ISSN: 0024-3639.

Patrick SW, Dudley J, Martin PR, Harrell FE, Warren MD, Hartmann KE, Ely EW, Grijalva CG, Cooper WO. Prescription opioid epidemic and infant outcomes. Pediatrics [print-electronic]. 2015 May; 135(5): 842-50. PMID: 25869370, PMCID: PMC4411781, PII: peds.2014-3299, DOI: 10.1542/peds.2014-3299, ISSN: 1098-4275.

Archer KR, Coronado RA, Haislip LR, Abraham CM, Vanston SW, Lazaro AE, Jackson JC, Ely EW, Guillamondegui OD, Obremskey WT. Telephone-based goal management training for adults with mild traumatic brain injury: study protocol for a randomized controlled trial. Trials. 2015; 16: 244. PMID: 26031289, PMCID: PMC4454274, PII: 10.1186/s13063-015-0775-1, DOI: 10.1186/s13063-015-0775-1, ISSN: 1745-6215.

Inoue S, Vasilevskis EE, Pandharipande PP, Girard TD, Graves AJ, Thompson J, Shintani A, Ely EW. The impact of lymphopenia on delirium in ICU patients. PLoS ONE. 2015; 10(5): e0126216. PMID: 25992641, PMCID: PMC4439144, PII: PONE-D-15-01328, DOI: 10.1371/journal.pone.0126216, ISSN: 1932-6203.

Casarin A, McAuley DF, Alce TM, Zhao X, Ely EW, Jackson JC, McDowell C, Agus A, Murphy L, Page VJ. Evaluating early administration of the hydroxymethylglutaryl-CoA reductase inhibitor simvastatin in the prevention and treatment of delirium in critically ill ventilated patients (MoDUS trial): study protocol for a randomized controlled trial. Trials. 2015; 16: 218. PMID: 25982544, PMCID: PMC4440514, PII: 10.1186/s13063-015-0731-0, DOI: 10.1186/s13063-015-0731-0, ISSN: 1745-6215.

Pfoh ER, Chan KS, Dinglas VD, Girard TD, Jackson JC, Morris PE, Hough CL, Mendez-Tellez PA, Ely EW, Huang M, Needham DM, Hopkins RO, . Cognitive screening among acute respiratory failure survivors: a cross-sectional evaluation of the Mini-Mental State Examination. Crit Care. 2015; 19: 220. PMID: 25939482, PMCID: PMC4480909, PII: 10.1186/s13054-015-0934-5, DOI: 10.1186/s13054-015-0934-5, ISSN: 1466-609X.

Trogrlic Z, van der Jagt M, Bakker J, Balas MC, Ely EW, van der Voort PH, Ista E. A systematic review of implementation strategies for assessment, prevention, and management of ICU delirium and their effect on clinical outcomes. Crit Care. 2015; 19: 157. PMID: 25888230, PMCID: PMC4428250, PII: 10.1186/s13054-015-0886-9, DOI: 10.1186/s13054-015-0886-9, ISSN: 1466-609X.

Neufeld KJ, Nelliot A, Inouye SK, Ely EW, Bienvenu OJ, Lee HB, Needham DM. Delirium diagnosis methodology used in research: a survey-based study. Am J Geriatr Psychiatry [print-electronic]. 2014 Dec; 22(12): 1513-21. PMID: 24745562, PMCID: PMC4164600, PII: S1064-7481(14)00090-6, DOI: 10.1016/j.jagp.2014.03.003, ISSN: 1545-7214.

Abraham CM, Obremskey WT, Song Y, Jackson JC, Ely EW, Archer KR. Hospital delirium and psychological distress at 1 year and health-related quality of life after moderate-to-severe traumatic injury without intracranial hemorrhage. Arch Phys Med Rehabil [print-electronic]. 2014 Dec; 95(12): 2382-9. PMID: 25175161, PII: S0003-9993(14)01008-9, DOI: 10.1016/j.apmr.2014.08.005, ISSN: 1532-821X.

Khan BA, Fadel WF, Tricker JL, Carlos WG, Farber MO, Hui SL, Campbell NL, Ely EW, Boustani MA. Effectiveness of implementing a wake up and breathe program on sedation and delirium in the ICU. Crit. Care Med. 2014 Dec; 42(12): e791-5. PMID: 25402299, PMCID: PMC4311879, PII: 00003246-201412000-00038, DOI: 10.1097/CCM.0000000000000660, ISSN: 1530-0293.

Han JH, Vasilevskis EE, Shintani A, Graves AJ, Schnelle JF, Dittus RS, Powers JS, Wilson A, Storrow AB, Ely EW. Impaired arousal at initial presentation predicts 6-month mortality: an analysis of 1084 acutely ill older patients. J Hosp Med [print-electronic]. 2014 Dec; 9(12): 772-8. PMID: 25352356, PMCID: PMC4326096, DOI: 10.1002/jhm.2276, ISSN: 1553-5606.

Andresen JM, Girard TD, Pandharipande PP, Davidson MA, Ely EW, Watson PL. Burst suppression on processed electroencephalography as a predictor of postcoma delirium in mechanically ventilated ICU patients. Crit. Care Med. 2014 Oct; 42(10): 2244-51. PMID: 25072756, PMCID: PMC4493889, DOI: 10.1097/CCM.0000000000000522, ISSN: 1530-0293.

Gaspardo P, Peressoni L, Comisso I, Mistraletti G, Ely EW, Morandi A. Delirium among critically ill adults: evaluation of the psychometric properties of the Italian 'Confusion Assessment Method for the Intensive Care Unit'. Intensive Crit Care Nurs [print-electronic]. 2014 Oct; 30(5): 283-91. PMID: 25059104, PII: S0964-3397(14)00042-1, DOI: 10.1016/j.iccn.2014.05.002, ISSN: 1532-4036.

Han JH, Schnelle JF, Ely EW. The relationship between a chief complaint of "altered mental status" and delirium in older emergency department patients. Acad Emerg Med [print-electronic]. 2014 Aug; 21(8): 937-40. PMID: 25154589, PMCID: PMC4150739, DOI: 10.1111/acem.12436, ISSN: 1553-2712.

Morandi A, Hughes CG, Thompson JL, Pandharipande PP, Shintani AK, Vasilevskis EE, Han JH, Jackson JC, Laskowitz DT, Bernard GR, Ely EW, Girard TD. Statins and delirium during critical illness: a multicenter, prospective cohort study. Crit. Care Med. 2014 Aug; 42(8): 1899-909. PMID: 24810528, PMCID: PMC4103957, DOI: 10.1097/CCM.0000000000000398, ISSN: 1530-0293.

Fudim M, Ely EW, Laffer CL, Elijovich F. Diagnosis of pheochromocytoma on physical examination. Eur. Heart J [print-electronic]. 2014 Jul; 35(26): 1705. PMID: 24334718, PII: eht536, DOI: 10.1093/eurheartj/eht536, ISSN: 1522-9645.

Ely EW. Our enlightened understanding of the risks of persistent delirium [letter]. Am. J. Respir. Crit. Care Med. 2014 Jun 6/1/2014; 189(11): 1442-3. PMID: 24881943, DOI: 10.1164/rccm.201403-0550LE, ISSN: 1535-4970.

Jackson JC, Santoro MJ, Ely TM, Boehm L, Kiehl AL, Anderson LS, Ely EW. Improving patient care through the prism of psychology: application of Maslow's hierarchy to sedation, delirium, and early mobility in the intensive care unit. J Crit Care [print-electronic]. 2014 Jun; 29(3): 438-44. PMID: 24636724, PMCID: PMC4718660, PII: S0883-9441(14)00037-9, DOI: 10.1016/j.jcrc.2014.01.009, ISSN: 1557-8615.

Balas MC, Vasilevskis EE, Olsen KM, Schmid KK, Shostrom V, Cohen MZ, Peitz G, Gannon DE, Sisson J, Sullivan J, Stothert JC, Lazure J, Nuss SL, Jawa RS, Freihaut F, Ely EW, Burke WJ. Effectiveness and safety of the awakening and breathing coordination, delirium monitoring/management, and early exercise/mobility bundle. Crit. Care Med. 2014 May; 42(5): 1024-36. PMID: 24394627, PMCID: PMC4105208, DOI: 10.1097/CCM.0000000000000129, ISSN: 1530-0293.

Jackson JC, Pandharipande PP, Girard TD, Brummel NE, Thompson JL, Hughes CG, Pun BT, Vasilevskis EE, Morandi A, Shintani AK, Hopkins RO, Bernard GR, Dittus RS, Ely EW, . Depression, post-traumatic stress disorder, and functional disability in survivors of critical illness in the BRAIN-ICU study: a longitudinal cohort study. Lancet Respir Med [print-electronic]. 2014 May; 2(5): 369-79. PMID: 24815803, PMCID: PMC4107313, PII: S2213-2600(14)70051-7, DOI: 10.1016/S2213-2600(14)70051-7, ISSN: 2213-2619.

Haglund NA, Schlendorf K, Keebler M, Gupta C, Maltais S, Ely EW, Lenihan D. Is a palpable pulse always restored during cardiopulmonary resuscitation in a patient with a left ventricular assist device?. Am. J. Med. Sci. 2014 Apr; 347(4): 322-7. PMID: 24508865, PII: S0002-9629(15)30367-0, DOI: 10.1097/MAJ.0000000000000219, ISSN: 1538-2990.

Watson PL, Malow BA, Ely EW. The authors reply [letter]. Crit. Care Med. 2014 Apr; 42(4): e313-4. PMID: 24633123, PII: 00003246-201404000-00065, DOI: 10.1097/CCM.0000000000000207, ISSN: 1530-0293.

Vasilevskis EE, Ely EW. 2013: updates in delirium. Neurohospitalist. 2014 Apr; 4(2): 58-60. PMID: 24707331, PMCID: PMC3975797, PII: 10.1177_1941874414524796, DOI: 10.1177/1941874414524796, ISSN: 1941-8744.

Brummel NE, Girard TD, Ely EW, Pandharipande PP, Morandi A, Hughes CG, Graves AJ, Shintani A, Murphy E, Work B, Pun BT, Boehm L, Gill TM, Dittus RS, Jackson JC. Feasibility and safety of early combined cognitive and physical therapy for critically ill medical and surgical patients: the Activity and Cognitive Therapy in ICU (ACT-ICU) trial. Intensive Care Med [print-electronic]. 2014 Mar; 40(3): 370-9. PMID: 24257969, PMCID: PMC3943568, DOI: 10.1007/s00134-013-3136-0, ISSN: 1432-1238.

Han JH, Wilson A, Graves AJ, Shintani A, Schnelle JF, Dittus RS, Powers JS, Vernon J, Storrow AB, Ely EW. Validation of the Confusion Assessment Method for the Intensive Care Unit in older emergency department patients. Acad Emerg Med. 2014 Feb; 21(2): 180-7. PMID: 24673674, PMCID: PMC4034173, DOI: 10.1111/acem.12309, ISSN: 1553-2712.

Brummel NE, Jackson JC, Pandharipande PP, Thompson JL, Shintani AK, Dittus RS, Gill TM, Bernard GR, Ely EW, Girard TD. Delirium in the ICU and subsequent long-term disability among survivors of mechanical ventilation. Crit. Care Med. 2014 Feb; 42(2): 369-77. PMID: 24158172, PMCID: PMC3947028, DOI: 10.1097/CCM.0b013e3182a645bd, ISSN: 1530-0293.

Brummel NE, Ely EW. Sedation level and the prevalence of delirium [letter]. Intensive Care Med [print-electronic]. 2014 Jan; 40(1): 135. PMID: 23982729, PMCID: PMC3869188, DOI: 10.1007/s00134-013-3083-9, ISSN: 1432-1238.

Almeida IC, Soares M, Bozza FA, Shinotsuka CR, Bujokas R, Souza-Dantas VC, Ely EW, Salluh JI. The impact of acute brain dysfunction in the outcomes of mechanically ventilated cancer patients. PLoS ONE. 2014; 9(1): e85332. PMID: 24465538, PMCID: PMC3899009, PII: PONE-D-13-31932, DOI: 10.1371/journal.pone.0085332, ISSN: 1932-6203.

Han JH, Wilson A, Vasilevskis EE, Shintani A, Schnelle JF, Dittus RS, Graves AJ, Storrow AB, Shuster J, Ely EW. Diagnosing delirium in older emergency department patients: validity and reliability of the delirium triage screen and the brief confusion assessment method. Ann Emerg Med [print-electronic]. 2013 Nov; 62(5): 457-65. PMID: 23916018, PMCID: PMC3936572, PII: S0196-0644(13)00436-8, DOI: 10.1016/j.annemergmed.2013.05.003, ISSN: 1097-6760.

Pandharipande PP, Girard TD, Jackson JC, Morandi A, Thompson JL, Pun BT, Brummel NE, Hughes CG, Vasilevskis EE, Shintani AK, Moons KG, Geevarghese SK, Canonico A, Hopkins RO, Bernard GR, Dittus RS, Ely EW, . Long-term cognitive impairment after critical illness. N. Engl. J. Med. 2013 Oct 10/3/2013; 369(14): 1306-16. PMID: 24088092, PMCID: PMC3922401, DOI: 10.1056/NEJMoa1301372, ISSN: 1533-4406.

Brummel NE, Vasilevskis EE, Han JH, Boehm L, Pun BT, Ely EW. Implementing delirium screening in the ICU: secrets to success. Crit. Care Med. 2013 Sep; 41(9): 2196-208. PMID: 23896832, PMCID: PMC3772682, DOI: 10.1097/CCM.0b013e31829a6f1e, ISSN: 1530-0293.

Page VJ, Ely EW, Gates S, Zhao XB, Alce T, Shintani A, Jackson J, Perkins GD, McAuley DF. Effect of intravenous haloperidol on the duration of delirium and coma in critically ill patients (Hope-ICU): a randomised, double-blind, placebo-controlled trial. Lancet Respir Med [print-electronic]. 2013 Sep; 1(7): 515-23. PMID: 24461612, PMCID: PMC4730945, PII: S2213-2600(13)70166-8, DOI: 10.1016/S2213-2600(13)70166-8, ISSN: 2213-2619.

Watson PL, Pandharipande P, Gehlbach BK, Thompson JL, Shintani AK, Dittus BS, Bernard GR, Malow BA, Ely EW. Atypical sleep in ventilated patients: empirical electroencephalography findings and the path toward revised ICU sleep scoring criteria. Crit. Care Med. 2013 Aug; 41(8): 1958-67. PMID: 23863228, PMCID: PMC3875326, PII: 00003246-201308000-00016, DOI: 10.1097/CCM.0b013e31828a3f75, ISSN: 1530-0293.

Watson PL, Pandharipande P, Gehlbach BK, Thompson JL, Shintani AK, Dittus BS, Bernard GR, Malow BA, Ely EW. Atypical Sleep in Ventilated Patients: Empirical Electroencephalography Findings and the Path Toward Revised ICU Sleep Scoring Criteria. Crit. Care Med [print-electronic]. 2013 Jun 6/12/2013; PMID: 23764974, DOI: 10.1097/CCM.0b01e1828af75, ISSN: 1530-0293.

Wang C, Wu Y, Yue P, Ely EW, Huang J, Yang X, Liu Y. Delirium assessment using Confusion Assessment Method for the Intensive Care Unit in Chinese critically ill patients. J Crit Care [print-electronic]. 2013 Jun; 28(3): 223-9. PMID: 23159138, PII: S0883-9441(12)00331-0, DOI: 10.1016/j.jcrc.2012.10.004, ISSN: 1557-8615.

Morandi A, Barnett N, Miller RR, Girard TD, Pandharipande PP, Ely EW, Ware LB. Vitamin D and delirium in critically ill patients: a preliminary investigation. J Crit Care [print-electronic]. 2013 Jun; 28(3): 230-5. PMID: 22884531, PMCID: PMC3498519, PII: S0883-9441(12)00186-4, DOI: 10.1016/j.jcrc.2012.06.011, ISSN: 1557-8615.

Smith HA, Brink E, Fuchs DC, Ely EW, Pandharipande PP. Pediatric delirium: monitoring and management in the pediatric intensive care unit. Pediatr. Clin. North Am [print-electronic]. 2013 Jun; 60(3): 741-60. PMID: 23639666, PII: S0031-3955(13)00024-2, DOI: 10.1016/j.pcl.2013.02.010, ISSN: 1557-8240.

Smith HA, Berutti T, Brink E, Strohler B, Fuchs DC, Ely EW, Pandharipande PP. Pediatric critical care perceptions on analgesia, sedation, and delirium. Semin Respir Crit Care Med [print-electronic]. 2013 Apr; 34(2): 244-61. PMID: 23716315, DOI: 10.1055/s-0033-1342987, ISSN: 1098-9048.

Jackson JC, Ely EW. Cognitive impairment after critical illness: etiologies, risk factors, and future directions. Semin Respir Crit Care Med [print-electronic]. 2013 Apr; 34(2): 216-22. PMID: 23716312, DOI: 10.1055/s-0033-1342984, ISSN: 1098-9048.

Ely EW, Barr J. Pain/agitation/delirium [editorial]. Semin Respir Crit Care Med [print-electronic]. 2013 Apr; 34(2): 151-2. PMID: 23716306, DOI: 10.1055/s-0033-1342974, ISSN: 1098-9048.

Hughes CG, Morandi A, Girard TD, Riedel B, Thompson JL, Shintani AK, Pun BT, Ely EW, Pandharipande PP. Association between endothelial dysfunction and acute brain dysfunction during critical illness. Anesthesiology. 2013 Mar; 118(3): 631-9. PMID: 23263016, PMCID: PMC3580006, DOI: 10.1097/ALN.0b013e31827bd193, ISSN: 1528-1175.

McPherson JA, Wagner CE, Boehm LM, Hall JD, Johnson DC, Miller LR, Burns KM, Thompson JL, Shintani AK, Ely EW, Pandharipande PP. Delirium in the cardiovascular ICU: exploring modifiable risk factors. Crit. Care Med. 2013 Feb; 41(2): 405-13. PMID: 23263581, PMCID: PMC3557701, DOI: 10.1097/CCM.0b013e31826ab49b, ISSN: 1530-0293.

Barr J, Fraser GL, Puntillo K, Ely EW, Gélinas C, Dasta JF, Davidson JE, Devlin JW, Kress JP, Joffe AM, Coursin DB, Herr DL, Tung A, Robinson BR, Fontaine DK, Ramsay MA, Riker RR, Sessler CN, Pun B, Skrobik Y, Jaeschke R, . Clinical practice guidelines for the management of pain, agitation, and delirium in adult patients in the intensive care unit. Crit. Care Med. 2013 Jan; 41(1): 263-306. PMID: 23269131, PII: 00003246-201301000-00029, DOI: 10.1097/CCM.0b013e3182783b72.

Barr J, Fraser GL, Puntillo K, Ely EW, Gélinas C, Dasta JF, Davidson JE, Devlin JW, Kress JP, Joffe AM, Coursin DB, Herr DL, Tung A, Robinson BR, Fontaine DK, Ramsay MA, Riker RR, Sessler CN, Pun B, Skrobik Y, Jaeschke R, . Clinical practice guidelines for the management of pain, agitation, and delirium in adult patients in the Intensive Care Unit: executive summary. Am J Health Syst Pharm. 2013 Jan 1/1/2013; 70(1): 53-8. PMID: 23261901, PII: 70/1/53.

Girard TD, Ware LB, Bernard GR, Pandharipande PP, Thompson JL, Shintani AK, Jackson JC, Dittus RS, Ely EW. Associations of markers of inflammation and coagulation with delirium during critical illness. Intensive Care Med [print-electronic]. 2012 Dec; 38(12): 1965-73. PMID: 22903241, PMCID: PMC3606929, DOI: 10.1007/s00134-012-2678-x, ISSN: 1432-1238.

Brummel NE, Jackson JC, Girard TD, Pandharipande PP, Schiro E, Work B, Pun BT, Boehm L, Gill TM, Ely EW. A combined early cognitive and physical rehabilitation program for people who are critically ill: the activity and cognitive therapy in the intensive care unit (ACT-ICU) trial. Phys Ther [print-electronic]. 2012 Dec; 92(12): 1580-92. PMID: 22577067, PMCID: PMC3513484, PII: ptj.20110414, DOI: 10.2522/ptj.20110414, ISSN: 1538-6724.

Seymour CW, Pandharipande PP, Koestner T, Hudson LD, Thompson JL, Shintani AK, Ely EW, Girard TD. Diurnal sedative changes during intensive care: impact on liberation from mechanical ventilation and delirium. Crit. Care Med. 2012 Oct; 40(10): 2788-96. PMID: 22824928, PMCID: PMC3576216, DOI: 10.1097/CCM.0b013e31825b8ade, ISSN: 1530-0293.

Vasilevskis EE, Ely EW. The Danger of Delirium: Comment on "Delirium and Long-term Cognitive Trajectory Among Persons With Dementia". Arch. Intern. Med. 2012 Sep 9/24/2012; 172(17): 1331-2. PMID: 22911486, PII: 1351355, DOI: 10.1001/archinternmed.2012.3414, ISSN: 1538-3679.

Vasilevskis EE, Han JH, Hughes CG, Ely EW. Epidemiology and risk factors for delirium across hospital settings. Best Pract Res Clin Anaesthesiol. 2012 Sep; 26(3): 277-87. PMID: 23040281, PMCID: PMC3580997, PII: S1521-6896(12)00036-5, DOI: 10.1016/j.bpa.2012.07.003, ISSN: 1878-1608.

Morandi A, Pandharipande PP, Jackson JC, Bellelli G, Trabucchi M, Ely EW. Understanding terminology of delirium and long-term cognitive impairment in critically ill patients. Best Pract Res Clin Anaesthesiol. 2012 Sep; 26(3): 267-76. PMID: 23040280, PII: S1521-6896(12)00051-1, DOI: 10.1016/j.bpa.2012.08.001, ISSN: 1878-1608.

Ely EW, Dittus RS, Girard TD. Point: should benzodiazepines be avoided in mechanically ventilated patients? Yes [editorial]. Chest. 2012 Aug; 142(2): 281-4; discussion 289. PMID: 22871750, PII: 1262315, DOI: 10.1378/chest.12-1189, ISSN: 1931-3543.

Gunther ML, Morandi A, Krauskopf E, Pandharipande P, Girard TD, Jackson JC, Thompson J, Shintani AK, Geevarghese S, Miller RR, Canonico A, Merkle K, Cannistraci CJ, Rogers BP, Gatenby JC, Heckers S, Gore JC, Hopkins RO, Ely EW, . The association between brain volumes, delirium duration, and cognitive outcomes in intensive care unit survivors: the VISIONS cohort magnetic resonance imaging study*. Crit. Care Med. 2012 Jul; 40(7): 2022-32. PMID: 22710202, PMCID: PMC3697780, PII: 00003246-201207000-00003, DOI: 10.1097/CCM.0b013e318250acc0, ISSN: 1530-0293.

Morandi A, Rogers BP, Gunther ML, Merkle K, Pandharipande P, Girard TD, Jackson JC, Thompson J, Shintani AK, Geevarghese S, Miller RR, Canonico A, Cannistraci CJ, Gore JC, Ely EW, Hopkins RO, . The relationship between delirium duration, white matter integrity, and cognitive impairment in intensive care unit survivors as determined by diffusion tensor imaging: the VISIONS prospective cohort magnetic resonance imaging study*. Crit. Care Med. 2012 Jul; 40(7): 2182-9. PMID: 22584766, PMCID: PMC3378755, DOI: 10.1097/CCM.0b013e318250acdc, ISSN: 1530-0293.

Kohli U, Pandharipande P, Muszkat M, Sofowora GG, Friedman EA, Scheinin M, Wood AJ, Ely EW, Tyndale RF, Choi L, Stein CM, Kurnik D. CYP2A6 genetic variation and dexmedetomidine disposition. Eur. J. Clin. Pharmacol [print-electronic]. 2012 Jun; 68(6): 937-42. PMID: 22271297, PMCID: PMC3352974, DOI: 10.1007/s00228-011-1208-z, ISSN: 1432-1041.

Jackson JC, Ely EW, Morey MC, Anderson VM, Denne LB, Clune J, Siebert CS, Archer KR, Torres R, Janz D, Schiro E, Jones J, Shintani AK, Levine B, Pun BT, Thompson J, Brummel NE, Hoenig H. Cognitive and physical rehabilitation of intensive care unit survivors: results of the RETURN randomized controlled pilot investigation. Crit. Care Med. 2012 Apr; 40(4): 1088-97. PMID: 22080631, PMCID: PMC3755871, DOI: 10.1097/CCM.0b013e3182373115, ISSN: 1530-0293.

Balas MC, Vasilevskis EE, Burke WJ, Boehm L, Pun BT, Olsen KM, Peitz GJ, Ely EW. Critical care nurses' role in implementing the "ABCDE bundle" into practice. Crit Care Nurse. 2012 Apr; 32(2): 35-8, 40. PMID: 22467611, PMCID: PMC3375171, PII: 32/2/35, DOI: 10.4037/ccn2012229, ISSN: 1940-8250.

Adams Wilson JR, Morandi A, Girard TD, Thompson JL, Boomershine CS, Shintani AK, Ely EW, Pandharipande PP. The association of the kynurenine pathway of tryptophan metabolism with acute brain dysfunction during critical illness*. Crit. Care Med. 2012 Mar; 40(3): 835-41. PMID: 22080637, PMCID: PMC3625666, DOI: 10.1097/CCM.0b013e318236f62d, ISSN: 1530-0293.

Franco JG, Ricardo C, Muñoz JF, de Pablo J, W P, Ely EW, Smith HA. Diagnosing delirium in critically ill children: Spanish translation and cultural adaptation of the Pediatric Confusion Assessment Method for the Intensive Care Unit [letter]. Crit. Care Med. 2012 Mar; 40(3): 1034. PMID: 22343876, PMCID: PMC3826446, PII: 00003246-201203000-00075, DOI: 10.1097/CCM.0b013e31823c8b1c, ISSN: 1530-0293.

Hipp DM, Ely EW. Pharmacological and nonpharmacological management of delirium in critically ill patients. Neurotherapeutics. 2012 Jan; 9(1): 158-75. PMID: 22270810, PMCID: PMC3271151, DOI: 10.1007/s13311-011-0102-9, ISSN: 1878-7479.

de Grahl C, Luetz A, Gratopp A, Gensel D, Mueller J, Smith H, Ely EW, Krude H, Spies C. The paediatric Confusion Assessment Method for the Intensive Care Unit (pCAM-ICU): translation and cognitive debriefing for the German-speaking area. Ger Med Sci [print-electronic]. 2012; 10: Doc07. PMID: 22557940, PMCID: PMC3334933, PII: 000158, DOI: 10.3205/000158, ISSN: 1612-3174.

Richards JE, Guillamondegui OD, Archer KR, Jackson JC, Ely EW, Obremskey WT. The association of reamed intramedullary nailing and long-term cognitive impairment. J Orthop Trauma. 2011 Dec; 25(12): 707-13. PMID: 22089759, PMCID: PMC3912993, PII: 00005131-201112000-00001, DOI: 10.1097/BOT.0b013e318225f358, ISSN: 1531-2291.

Pandharipande PP, Ely EW. Sedation and analgesia in the ICU: pharmacology, protocolization, and clinical consequences. Preface. Anesthesiol Clin. 2011 Dec; 29(4): xv-xvi. PMID: 22078923, PII: S1932-2275(11)00088-7, DOI: 10.1016/j.anclin.2011.10.001, ISSN: 1932-2275.

Smith HA, Fuchs DC, Pandharipande PP, Barr FE, Ely EW. Delirium: an emerging frontier in the management of critically ill children. Anesthesiol Clin. 2011 Dec; 29(4): 729-50. PMID: 22078920, PII: S1932-2275(11)00086-3, DOI: 10.1016/j.anclin.2011.09.011, ISSN: 1932-2275.

Vasilevskis EE, Morandi A, Boehm L, Pandharipande PP, Girard TD, Jackson JC, Thompson JL, Shintani A, Gordon SM, Pun BT, Ely EW. Delirium and sedation recognition using validated instruments: reliability of bedside intensive care unit nursing assessments from 2007 to 2010. J Am Geriatr Soc. 2011 Nov; 59 Suppl 2: S249-55. PMID: 22091569, PMCID: PMC3233973, DOI: 10.1111/j.1532-5415.2011.03673.x, ISSN: 1532-5415.

Choi L, Caffo BS, Kohli U, Pandharipande P, Kurnik D, Ely EW, Stein CM. A Bayesian hierarchical nonlinear mixture model in the presence of artifactual outliers in a population pharmacokinetic study. J Pharmacokinet Pharmacodyn [print-electronic]. 2011 Oct; 38(5): 613-36. PMID: 21847635, PMCID: PMC3182101, DOI: 10.1007/s10928-011-9211-7, ISSN: 1573-8744.

Jackson JC, Archer KR, Bauer R, Abraham CM, Song Y, Greevey R, Guillamondegui O, Ely EW, Obremskey W. A prospective investigation of long-term cognitive impairment and psychological distress in moderately versus severely injured trauma intensive care unit survivors without intracranial hemorrhage. J Trauma. 2011 Oct; 71(4): 860-6. PMID: 21537211, DOI: 10.1097/TA.0b013e3182151961, ISSN: 1529-8809.

Morandi A, Hughes CG, Girard TD, McAuley DF, Ely EW, Pandharipande PP. Statins and brain dysfunction: a hypothesis to reduce the burden of cognitive impairment in patients who are critically ill. Chest. 2011 Sep; 140(3): 580-5. PMID: 21896517, PMCID: PMC3168859, PII: 140/3/580, DOI: 10.1378/chest.10-3065, ISSN: 1931-3543.

Morandi A, Gunther ML, Pandharipande PP, Jackson JC, Thompson JL, Shintani AK, Ely EW, Girard TD. Insulin-like growth factor-1 and delirium in critically ill mechanically ventilated patients: a preliminary investigation. Int Psychogeriatr [print-electronic]. 2011 Sep; 23(7): 1175-81. PMID: 21294938, PMCID: PMC3654518, PII: S1041610210002486, DOI: 10.1017/S1041610210002486, ISSN: 1741-203X.

Ely EW. A piece of my mind. Cyanosis. JAMA. 2011 Jun 6/15/2011; 305(23): 2388-9. PMID: 21673285, PII: 305/23/2388, DOI: 10.1001/jama.2011.816, ISSN: 1538-3598.

Morandi A, Vasilevskis EE, Pandharipande PP, Girard TD, Solberg LM, Neal EB, Koestner T, Torres R, Thompson JL, Shintani AK, Han JH, Schnelle J, Fick DM, Ely EW, Kripalani S. Inappropriate medications in elderly ICU survivors: where to intervene?. Arch. Intern. Med. 2011 Jun 6/13/2011; 171(11): 1032-4. PMID: 21670372, PMCID: PMC3575737, PII: 171/11/1032, DOI: 10.1001/archinternmed.2011.233, ISSN: 1538-3679.

Han JH, Bryce SN, Ely EW, Kripalani S, Morandi A, Shintani A, Jackson JC, Storrow AB, Dittus RS, Schnelle J. The effect of cognitive impairment on the accuracy of the presenting complaint and discharge instruction comprehension in older emergency department patients. Ann Emerg Med [print-electronic]. 2011 Jun; 57(6): 662-671.e2. PMID: 21272958, PMCID: PMC3603343, PII: S0196-0644(10)01834-2, DOI: 10.1016/j.annemergmed.2010.12.002, ISSN: 1097-6760.

Han JH, Eden S, Shintani A, Morandi A, Schnelle J, Dittus RS, Storrow AB, Ely EW. Delirium in older emergency department patients is an independent predictor of hospital length of stay. Acad Emerg Med [print-electronic]. 2011 May; 18(5): 451-7. PMID: 21521405, PMCID: PMC3768130, DOI: 10.1111/j.1553-2712.2011.01065.x, ISSN: 1553-2712.

Speroff T, Ely EW, Greevy R, Weinger MB, Talbot TR, Wall RJ, Deshpande JK, France DJ, Nwosu S, Burgess H, Englebright J, Williams MV, Dittus RS. Quality improvement projects targeting health care-associated infections: comparing Virtual Collaborative and Toolkit approaches. J Hosp Med [print-electronic]. 2011 May; 6(5): 271-8. PMID: 21312329, DOI: 10.1002/jhm.873, ISSN: 1553-5606.

Guillamondegui OD, Richards JE, Ely EW, Jackson JC, Archer KR, Norris PR, Obremskey WT. Does hypoxia affect intensive care unit delirium or long-term cognitive impairment after multiple trauma without intracranial hemorrhage?. J Trauma. 2011 Apr; 70(4): 910-5. PMID: 21610396, PII: 00005373-201104000-00023, DOI: 10.1097/TA.0b013e3182114f18, ISSN: 1529-8809.

Morandi A, Brummel NE, Ely EW. Sedation, delirium and mechanical ventilation: the 'ABCDE' approach. Curr Opin Crit Care. 2011 Feb; 17(1): 43-9. PMID: 21169829, DOI: 10.1097/MCC.0b013e3283427243, ISSN: 1531-7072.

Rice TW, Ware LB, Haponik EF, Chiles C, Wheeler AP, Bernard GR, Steingrub JS, Hite RD, Matthay MA, Wright P, Ely EW, . Vascular pedicle width in acute lung injury: correlation with intravascular pressures and ability to discriminate fluid status. Crit Care [print-electronic]. 2011; 15(2): R86. PMID: 21385351, PMCID: PMC3219344, PII: cc10084, DOI: 10.1186/cc10084, ISSN: 1466-609X.

McGrane S, Girard TD, Thompson JL, Shintani AK, Woodworth A, Ely EW, Pandharipande PP. Procalcitonin and C-reactive protein levels at admission as predictors of duration of acute brain dysfunction in critically ill patients. Crit Care [print-electronic]. 2011; 15(2): R78. PMID: 21366899, PMCID: PMC3219330, PII: cc10070, DOI: 10.1186/cc10070, ISSN: 1466-609X.

Smith HA, Boyd J, Fuchs DC, Melvin K, Berry P, Shintani A, Eden SK, Terrell MK, Boswell T, Wolfram K, Sopfe J, Barr FE, Pandharipande PP, Ely EW. Diagnosing delirium in critically ill children: Validity and reliability of the Pediatric Confusion Assessment Method for the Intensive Care Unit. Crit. Care Med. 2011 Jan; 39(1): 150-7. PMID: 20959783, PMCID: PMC3776416, DOI: 10.1097/CCM.0b013e3181feb489, ISSN: 1530-0293.

Speroff T, Nwosu S, Greevy R, Weinger MB, Talbot TR, Wall RJ, Deshpande JK, France DJ, Ely EW, Burgess H, Englebright J, Williams MV, Dittus RS. Organisational culture: variation across hospitals and connection to patient safety climate. Qual Saf Health Care. 2010 Dec; 19(6): 592-6. PMID: 21127115, PII: 19/6/592, DOI: 10.1136/qshc.2009.039511, ISSN: 1475-3901.

Vasilevskis EE, Ely EW, Speroff T, Pun BT, Boehm L, Dittus RS. Reducing iatrogenic risks: ICU-acquired delirium and weakness--crossing the quality chasm. Chest. 2010 Nov; 138(5): 1224-33. PMID: 21051398, PMCID: PMC4694109, PII: 138/5/1224, DOI: 10.1378/chest.10-0466, ISSN: 1931-3543.

Vasilevskis EE, Pandharipande PP, Girard TD, Ely EW. A screening, prevention, and restoration model for saving the injured brain in intensive care unit survivors. Crit. Care Med. 2010 Oct; 38(10 Suppl): S683-91. PMID: 21164415, PMCID: PMC3679543, PII: 00003246-201010001-00027, DOI: 10.1097/CCM.0b013e3181f245d3, ISSN: 1530-0293.

Morandi A, Gunther ML, Vasilevskis EE, Girard TD, Hopkins RO, Jackson JC, Pandharipande P, Ely EW. Neuroimaging in delirious intensive care unit patients: a preliminary case series report. Psychiatry (Edgmont). 2010 Sep; 7(9): 28-33. PMID: 20941349, PMCID: PMC2952644, ISSN: 1555-5194.

Jacobowski NL, Girard TD, Mulder JA, Ely EW. Communication in critical care: family rounds in the intensive care unit. Am. J. Crit. Care. 2010 Sep; 19(5): 421-30. PMID: 20810417, PMCID: PMC3707491, PII: 19/5/421, DOI: 10.4037/ajcc2010656, ISSN: 1937-710X.

Agarwal V, O'Neill PJ, Cotton BA, Pun BT, Haney S, Thompson J, Kassebaum N, Shintani A, Guy J, Ely EW, Pandharipande P. Prevalence and risk factors for development of delirium in burn intensive care unit patients. J Burn Care Res. 2010 Sep; 31(5): 706-15. PMID: 20647937, PMCID: PMC3773484, DOI: 10.1097/BCR.0b013e3181eebee9, ISSN: 1559-0488.

Janz DR, Abel TW, Jackson JC, Gunther ML, Heckers S, Ely EW. Brain autopsy findings in intensive care unit patients previously suffering from delirium: a pilot study. J Crit Care [print-electronic]. 2010 Sep; 25(3): 538.e7-12. PMID: 20580199, PMCID: PMC3755870, PII: S0883-9441(10)00126-7, DOI: 10.1016/j.jcrc.2010.05.004, ISSN: 1557-8615.

Han JH, Shintani A, Eden S, Morandi A, Solberg LM, Schnelle J, Dittus RS, Storrow AB, Ely EW. Delirium in the emergency department: an independent predictor of death within 6 months. Ann Emerg Med [print-electronic]. 2010 Sep; 56(3): 244-252.e1. PMID: 20363527, PMCID: PMC3768121, PII: S0196-0644(10)00220-9, DOI: 10.1016/j.annemergmed.2010.03.003, ISSN: 1097-6760.

Han JH, Wilson A, Ely EW. Delirium in the older emergency department patient: a quiet epidemic. Emerg. Med. Clin. North Am. 2010 Aug; 28(3): 611-31. PMID: 20709246, PMCID: PMC3708798, PII: S0733-8627(10)00034-9, DOI: 10.1016/j.emc.2010.03.005, ISSN: 1558-0539.

Jackson JC, Girard TD, Gordon SM, Thompson JL, Shintani AK, Thomason JW, Pun BT, Canonico AE, Dunn JG, Bernard GR, Dittus RS, Ely EW. Long-term cognitive and psychological outcomes in the awakening and breathing controlled trial. Am. J. Respir. Crit. Care Med [print-electronic]. 2010 Jul 7/15/2010; 182(2): 183-91. PMID: 20299535, PMCID: PMC2913233, PII: 200903-0442OC, DOI: 10.1164/rccm.200903-0442OC, ISSN: 1535-4970.

Girard TD, Jackson JC, Pandharipande PP, Pun BT, Thompson JL, Shintani AK, Gordon SM, Canonico AE, Dittus RS, Bernard GR, Ely EW. Delirium as a predictor of long-term cognitive impairment in survivors of critical illness. Crit. Care Med. 2010 Jul; 38(7): 1513-20. PMID: 20473145, PMCID: PMC3638813, DOI: 10.1097/CCM.0b013e3181e47be1, ISSN: 1530-0293.

King MS, Render ML, Ely EW, Watson PL. Liberation and animation: strategies to minimize brain dysfunction in critically ill patients. Semin Respir Crit Care Med [print-electronic]. 2010 Feb; 31(1): 87-96. PMID: 20101551, DOI: 10.1055/s-0029-1246284, ISSN: 1098-9048.

Girard TD, Pandharipande PP, Carson SS, Schmidt GA, Wright PE, Canonico AE, Pun BT, Thompson JL, Shintani AK, Meltzer HY, Bernard GR, Dittus RS, Ely EW, . Feasibility, efficacy, and safety of antipsychotics for intensive care unit delirium: the MIND randomized, placebo-controlled trial. Crit. Care Med. 2010 Feb; 38(2): 428-37. PMID: 20095068, PMCID: PMC3645269, ISSN: 1530-0293.

Pandharipande P, Banerjee A, McGrane S, Ely EW. Liberation and animation for ventilated ICU patients: the ABCDE bundle for the back-end of critical care. Crit Care [print-electronic]. 2010; 14(3): 157. PMID: 20497606, PMCID: PMC2911702, PII: cc8999, DOI: 10.1186/cc8999, ISSN: 1466-609X.

Chumbler NR, Quigley P, Sanford J, Griffiths P, Rose D, Morey M, Ely EW, Hoenig H. Implementing telerehabilitation research for stroke rehabilitation with community dwelling veterans: lessons learned. Int J Telerehabil. 2010; 2(1): 15-22. PMID: 25945169, PMCID: PMC4296788, PII: v2n1-art-10.5195-ijt.2010.6047, DOI: 10.5195/ijt.2010.6047, ISSN: 1945-2020.

Pandharipande PP, Sanders RD, Girard TD, McGrane S, Thompson JL, Shintani AK, Herr DL, Maze M, Ely EW, . Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial. Crit Care [print-electronic]. 2010; 14(2): R38. PMID: 20233428, PMCID: PMC2887145, PII: cc8916, DOI: 10.1186/cc8916, ISSN: 1466-609X.

Jackson JC, Hopkins RO, Miller RR, Gordon SM, Wheeler AP, Ely EW. Acute respiratory distress syndrome, sepsis, and cognitive decline: a review and case study. South. Med. J. 2009 Nov; 102(11): 1150-7. PMID: 19864995, PMCID: PMC3776422, DOI: 10.1097/SMJ.0b013e3181b6a592, ISSN: 1541-8243.

Shintani AK, Girard TD, Eden SK, Arbogast PG, Moons KG, Ely EW. Immortal time bias in critical care research: application of time-varying Cox regression for observational cohort studies. Crit. Care Med. 2009 Nov; 37(11): 2939-45. PMID: 19770737, PMCID: PMC3365557, DOI: 10.1097/CCM.0b013e3181b7fbbb, ISSN: 1530-0293.