Late in 2001, she appeared in The Shipping News (2001) with Scott Glenn. Glenn had played Jack Crawford in The Silence of the Lambs (1991). Moore appeared in the sequel, Hannibal (2001).
After Jodie Foster turned down the chance to reprise her Oscar-winning role of Clarice Starling in Hannibal (2001), several actresses were considered for the part - Moore triumphed over such contenders as Helen Hunt, Gillian Anderson and Cate Blanchett.
Born Julie Anne Smith, she had to change her name when she registered with the Actor's Guild as every variation of her name seemed to be taken. She then combined her first two names and assumed her father's middle name as her surname.
Was considered for the lead role of Kate McQueen in Fair Game (1995). The part eventually went to Cindy Crawford.
Received triple nominations from the Screen Actors Guild Awards in both 2000 and 2003.
She and her The End of the Affair (1999) co-star Ralph Fiennes have acted in separate Hannibal Lecter films: she in Hannibal (2001) and he in Red Dragon (2002).
Born on the same day as actress Daryl Hannah. She also shares a birthday with actor Brendan Fraser.
She reads every script she receives.
She is one of the elite ten thespians to have been nominated for both a Supporting and a Lead Acting Academy Award in the same year. In 2003, she was nominated for a Supporting Oscar for her role in The Hours (2002), and in the Lead category for her role in Far from Heaven (2002). The other nine are Fay Bainter, Teresa Wright, Barry Fitzgerald (he has been nominated in both categories for the same role in the same movie), Jessica Lange, Al Pacino, Sigourney Weaver, Emma Thompson, Holly Hunter, Cate Blanchett and Jamie Foxx.
In order to convincingly portray the role of a housewife suffering from an immune disorder in Safe (1995), she lost 10 pounds off of her already petite frame.
Her brother, Peter Moore Smith, is an author and has written the book "Raveling" for which Julianne Moore has bought the film rights.
She and Joan Cusack played pregnant women in Nine Months (1995). In 1997, their own sons were born.
Was considered for the lead role of "Deirdre Burroughs" in Running with Scissors (2006). The part eventually went to Annette Bening.
Is a staunch pro-choice advocate and an active member of Planned Parenthood.
Louis Malle, who directed her in the 1994 movie version, Vanya on 42nd Street (1994), said "that she made him think of the greatest of all ravaged beauties, Jeanne Moreau."
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