(Translated by https://www.hiragana.jp/)
KEGG PATHWAY: ptr05152
KEGG   PATHWAY: ptr05152
Entry
ptr05152                    Pathway                                
Name
Tuberculosis - Pan troglodytes (chimpanzee)
Description
Tuberculosis, or TB, is an infectious disease caused by Mycobacterium tuberculosis. One third of the world's population is thought to be infected with TB. About 90% of those infected result in latent infections, and about 10% of latent infections develop active diseases when their immune system is impaired due to the age, other diseases such as AIDS or exposure to immunosuppressive drugs. TB is transmitted through the air and primarily attacks the lungs, then it can spread by the circulatory system to other parts of body. Once TB bacilli have entered the host by the respiratory route and infected macrophages in the lungs, they interfere with phagosomal maturation, antigen presentation, apoptosis and host immune system to establish persistent or latent infection.
Class
Human Diseases; Infectious disease: bacterial
Pathway map
ptr05152  Tuberculosis
ptr05152

Organism
Pan troglodytes (chimpanzee) [GN:ptr]
Gene
494186  TNF; tumor necrosis factor [KO:K03156]
466934  TNFRSF1A; tumor necrosis factor receptor superfamily member 1A isoform X1 [KO:K03158]
454154  TRADD; tumor necrosis factor receptor type 1-associated DEATH domain protein isoform X2 [KO:K03171]
451389  FADD; FAS-associated death domain protein [KO:K02373]
746477  CASP8; caspase-8 isoform X9 [KO:K04398] [EC:3.4.22.61]
459873  CASP10; caspase-10 isoform X1 [KO:K04400] [EC:3.4.22.63]
461669  CASP3; caspase-3 isoform X2 [KO:K02187] [EC:3.4.22.56]
458635  BID; BH3-interacting domain death agonist isoform X2 [KO:K04726]
747093  BAX; apoptosis regulator BAX isoform X4 [KO:K02159]
742456  cytochrome c-like [KO:K08738]
744779  CYCS; cytochrome c isoform X1 [KO:K08738]
107972317  cytochrome c-like [KO:K08738]
104002760  cytochrome c [KO:K08738]
107967841  cytochrome c-like [KO:K08738]
107967209  cytochrome c-like [KO:K08738]
112204199  cytochrome c-like [KO:K08738]
107973044  cytochrome c-like isoform X1 [KO:K08738]
107970561  cytochrome c, somatic-like [KO:K08738]
129135691  cytochrome c-like [KO:K08738]
129137450  cytochrome c-like [KO:K08738]
456457  CASP9; caspase-9 isoform X2 [KO:K04399] [EC:3.4.22.62]
452153  APAF1; apoptotic protease-activating factor 1 isoform X2 [KO:K02084]
456035  AKT2; RAC-beta serine/threonine-protein kinase isoform X6 [KO:K04456] [EC:2.7.11.1]
740898  AKT1; RAC-alpha serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
100609583  AKT3; RAC-gamma serine/threonine-protein kinase isoform X1 [KO:K04456] [EC:2.7.11.1]
100615623  BAD; bcl2-associated agonist of cell death isoform X1 [KO:K02158]
738409  BCL2; apoptosis regulator Bcl-2 isoform X1 [KO:K02161]
461445  CAMK2D; calcium/calmodulin-dependent protein kinase type II subunit delta isoform X3 [KO:K04515] [EC:2.7.11.17]
462189  CAMK2A; calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1 [KO:K04515] [EC:2.7.11.17]
738330  CAMK2G; calcium/calmodulin-dependent protein kinase type II subunit gamma isoform X4 [KO:K04515] [EC:2.7.11.17]
738167  CAMK2B; calcium/calmodulin-dependent protein kinase type II subunit beta isoform X1 [KO:K04515] [EC:2.7.11.17]
449517  IFNG; interferon gamma precursor [KO:K04687]
747276  IFNGR1; interferon gamma receptor 1 isoform X1 [KO:K05132]
470077  IFNGR2; interferon gamma receptor 2 isoform X2 [KO:K05133]
743373  JAK1; tyrosine-protein kinase JAK1 isoform X1 [KO:K11217] [EC:2.7.10.2]
464979  JAK2; tyrosine-protein kinase JAK2 isoform X1 [KO:K04447] [EC:2.7.10.2]
459834  STAT1; signal transducer and activator of transcription 1-alpha/beta isoform X2 [KO:K11220]
453914  CIITA; MHC class II transactivator isoform X1 [KO:K08060] [EC:2.7.11.1]
457292  RFX5; DNA-binding protein RFX5 isoform X2 [KO:K08061]
455872  RFXANK; DNA-binding protein RFXANK isoform X4 [KO:K08062]
100610983  RFXAP; regulatory factor X-associated protein isoform X2 [KO:K08063]
748395  NFYA; nuclear transcription factor Y subunit alpha isoform X7 [KO:K08064]
452191  NFYB; nuclear transcription factor Y subunit beta isoform X1 [KO:K08065]
456799  NFYC; nuclear transcription factor Y subunit gamma isoform X3 [KO:K08066]
459901  CREB1; cyclic AMP-responsive element-binding protein 1 isoform X1 [KO:K05870]
449592  PATR-DMB; major histocompatibility complex, class II, DM beta precursor [KO:K06752]
471974  PATR-DQA1; HLA class II histocompatibility antigen, DQ alpha 1 chain isoform X2 [KO:K06752]
471976  PATR-DQA2; HLA class II histocompatibility antigen, DQ alpha 2 chain [KO:K06752]
471977  PATR-DOB; patr class II histocompatibility antigen, DO beta chain precursor [KO:K06752]
462591  PATR-DRA; major histocompatibility complex, class II, DR alpha precursor [KO:K06752]
462594  PATR-DQB1; major histocompatibility complex, class II, DQ beta 1 precursor [KO:K06752]
462598  PATR-DPA1; HLA class II histocompatibility antigen, DP alpha 1 chain isoform X1 [KO:K06752]
462599  PATR-DPB1; HLA class II histocompatibility antigen, DP beta 1 chain isoform X1 [KO:K06752]
462592  PATR-DRB5; major histocompatibility complex, class II, DR beta 5 precursor [KO:K06752]
104006793  HLA class II histocompatibility antigen, DR beta 3 chain precursor [KO:K06752]
100616520  HLA class II histocompatibility antigen, DQ beta 1 chain isoform X5 [KO:K06752]
100608816  MAMU-DMA; HLA class II histocompatibility antigen, DM alpha chain isoform X1 [KO:K06752]
100610904  HLA class II histocompatibility antigen, DP beta 1 chain-like isoform X3 [KO:K06752]
462191  CD74; HLA class II histocompatibility antigen gamma chain [KO:K06505]
467891  CREBBP; CREB-binding protein isoform X6 [KO:K04498] [EC:2.3.1.48]
458862  EP300; histone acetyltransferase P300 [KO:K04498] [EC:2.3.1.48]
469657  IL10; interleukin-10 isoform X2 [KO:K05443]
451580  IL10RA; interleukin-10 receptor subunit alpha isoform X2 [KO:K05134]
473966  IL10RB; interleukin-10 receptor subunit beta isoform X1 [KO:K05135]
457277  CTSS; cathepsin S [KO:K01368] [EC:3.4.22.27]
735637  CLEC4E; C-type lectin domain family 4 member E isoform X2 [KO:K10059]
100612300  FCER1G; high affinity immunoglobulin epsilon receptor subunit gamma [KO:K07983]
458229  SRC; proto-oncogene tyrosine-protein kinase Src isoform X1 [KO:K05704] [EC:2.7.10.2]
464586  SYK; tyrosine-protein kinase SYK isoform X1 [KO:K05855] [EC:2.7.10.2]
464917  CARD9; caspase recruitment domain-containing protein 9 isoform X4 [KO:K12794]
468549  MALT1; mucosa-associated lymphoid tissue lymphoma translocation protein 1 isoform X3 [KO:K07369] [EC:3.4.22.-]
456984  BCL10; B-cell lymphoma/leukemia 10 isoform X2 [KO:K07368]
454083  NOD2; nucleotide-binding oligomerization domain-containing protein 2 [KO:K10165]
464277  RIPK2; receptor-interacting serine/threonine-protein kinase 2 isoform X2 [KO:K08846] [EC:2.7.11.1]
462099  HSPA9; stress-70 protein, mitochondrial isoform X1 [KO:K04043]
459852  HSPD1; 60 kDa heat shock protein, mitochondrial [KO:K04077] [EC:5.6.1.7]
458239  LBP; lipopolysaccharide-binding protein isoform X1 [KO:K05399]
471325  TLR2; toll-like receptor 2 precursor [KO:K10159]
461167  TLR1; toll-like receptor 1 precursor [KO:K05398]
471167  TLR6; toll-like receptor 6 [KO:K10169]
743242  TLR4; toll-like receptor 4 precursor [KO:K10160]
462118  CD14; monocyte differentiation antigen CD14 precursor [KO:K04391]
451654  TIRAP; toll/interleukin-1 receptor domain-containing adapter protein [KO:K05403]
460269  MYD88; myeloid differentiation primary response protein MyD88 [KO:K04729]
466962  IRAK4; interleukin-1 receptor-associated kinase 4 isoform X1 [KO:K04733] [EC:2.7.11.1]
465935  IRAK1; interleukin-1 receptor-associated kinase 1 isoform X1 [KO:K04730] [EC:2.7.11.1]
460165  IRAK2; interleukin-1 receptor-associated kinase-like 2 [KO:K04731] [EC:2.7.11.1]
451702  TRAF6; TNF receptor-associated factor 6 isoform X1 [KO:K03175] [EC:2.3.2.27]
461406  NFKB1; nuclear factor NF-kappa-B p105 subunit isoform X3 [KO:K02580]
466665  RELA; transcription factor P65 [KO:K04735]
450161  MAPK14; mitogen-activated protein kinase 14 [KO:K04441] [EC:2.7.11.24]
462644  MAPK13; mitogen-activated protein kinase 13 [KO:K04441] [EC:2.7.11.24]
747077  MAPK12; mitogen-activated protein kinase 12 isoform X1 [KO:K04441] [EC:2.7.11.24]
104003820  MAPK11; mitogen-activated protein kinase 11 [KO:K04441] [EC:2.7.11.24]
454037  MAPK3; mitogen-activated protein kinase 3 [KO:K04371] [EC:2.7.11.24]
458680  MAPK1; mitogen-activated protein kinase 1 [KO:K04371] [EC:2.7.11.24]
450445  MAPK8; mitogen-activated protein kinase 8 isoform X1 [KO:K04440] [EC:2.7.11.24]
462336  MAPK9; mitogen-activated protein kinase 9 isoform X2 [KO:K04440] [EC:2.7.11.24]
461358  MAPK10; mitogen-activated protein kinase 10 isoform X1 [KO:K04440] [EC:2.7.11.24]
455026  NOS2; nitric oxide synthase, inducible isoform X1 [KO:K13241] [EC:1.14.13.39]
463288  IL6; interleukin-6 isoform X1 [KO:K05405]
460816  IL12A; interleukin-12 subunit alpha isoform X1 [KO:K05406]
471723  IL12B; interleukin-12 subunit beta [KO:K05425]
739011  IL18; interleukin-18 isoform X1 [KO:K05482]
467036  IL23A; interleukin-23 subunit alpha [KO:K05426]
470485  IL1A; interleukin-1 alpha [KO:K04383]
450200  IL1B; interleukin-1 beta [KO:K04519]
469969  CEBPB; CCAAT/enhancer-binding protein beta [KO:K10048]
100612381  CEBPG; CCAAT/enhancer-binding protein gamma [KO:K10049]
470827  TWF2; toll-like receptor 9 [KO:K10161]
473185  IFNA21; interferon alpha-21 [KO:K05414]
473193  IFNA14; interferon alpha-14 [KO:K05414]
473196  IFNA6; interferon alpha-6 [KO:K05414]
473198  IFNA2; interferon alpha-2 [KO:K05414]
473199  IFNA8; interferon alpha-8 [KO:K05414]
741660  interferon alpha-17 [KO:K05414]
473195  IFNA5; interferon alpha-5 [KO:K05414]
741747  interferon alpha-7 [KO:K05414]
742651  interferon alpha-1/13 [KO:K05414]
741978  interferon alpha-16 [KO:K05414]
744748  interferon alpha-17 [KO:K05414]
473191  interferon alpha-17 [KO:K05414]
473197  interferon alpha-1/13 [KO:K05414]
741797  interferon alpha-4 [KO:K05414]
473183  IFNB1; interferon beta [KO:K05415]
455661  CLEC4M; C-type lectin domain family 4 member M [KO:K06563]
742818  CD209L2; CD209 antigen-like protein E [KO:K06563]
450160  CD209; CD209 antigen [KO:K06563]
451618  ARHGEF12; rho guanine nucleotide exchange factor 12 isoform X1 [KO:K07532]
461014  RHOA; transforming protein RhoA isoform X1 [KO:K04513]
459394  LSP1; lymphocyte-specific protein 1 isoform X1 [KO:K14957]
134807782  uncharacterized protein LOC134807782 [KO:K14957]
456546  PLK3; serine/threonine-protein kinase PLK3 isoform X1 [KO:K08862] [EC:2.7.11.21]
454518  KSR1; kinase suppressor of Ras 1 isoform X1 [KO:K14958]
460182  RAF1; RAF proto-oncogene serine/threonine-protein kinase isoform X1 [KO:K04366] [EC:2.7.11.1]
456060  TGFB1; transforming growth factor beta-1 proprotein isoform X3 [KO:K13375]
457742  TGFB2; transforming growth factor beta-2 proprotein isoform X1 [KO:K13376]
453054  TGFB3; transforming growth factor beta-3 proprotein isoform X2 [KO:K13377]
452027  CYP27B1; 25-hydroxyvitamin D-1 alpha hydroxylase, mitochondrial [KO:K07438] [EC:1.14.15.18]
451858  VDR; vitamin D3 receptor isoform X1 [KO:K08539]
741881  CAMP; cathelicidin antimicrobial peptide precursor [KO:K13916]
455644  C3; complement C3 [KO:K03990]
449643  CR1; complement receptor type 1 precursor [KO:K04011]
454070  ITGAX; integrin alpha-X isoform X1 [KO:K06462]
458607  ITGB2; integrin beta-2 isoform X2 [KO:K06464]
454069  ITGAM; integrin alpha-M precursor [KO:K06461]
450333  MRC1; macrophage mannose receptor 1 isoform X2 [KO:K06560]
739140  PLA2R1; secretory phospholipase A2 receptor isoform X1 [KO:K06560]
454788  MRC2; C-type mannose receptor 2 [KO:K06560]
738821  SPHK1; sphingosine kinase 1 isoform X1 [KO:K04718] [EC:2.7.1.91]
468943  SPHK2; sphingosine kinase 2 isoform X1 [KO:K04718] [EC:2.7.1.91]
737566  CALML5; calmodulin-like protein 5 [KO:K02183]
466008  CALML3; calmodulin-like protein 3 [KO:K02183]
738819  CALM1; calmodulin-1 [KO:K02183]
743250  CALML6; calmodulin-like protein 6 isoform X1 [KO:K02183]
453534  CALML4; calmodulin-like protein 4 isoform X2 [KO:K02183]
468313  calmodulin-2-like [KO:K02183]
456153  CALM3; calmodulin-3 [KO:K02183]
459213  CALM2; calmodulin-2 [KO:K02183]
455385  PIK3C3; phosphatidylinositol 3-kinase catalytic subunit type 3 isoform X1 [KO:K00914] [EC:2.7.1.137]
460217  RAB5A; ras-related protein Rab-5A [KO:K07887]
746457  RAB5B; ras-related protein Rab-5B [KO:K07888]
454678  RAB5C; ras-related protein Rab-5C isoform X2 [KO:K07889]
467212  EEA1; early endosome antigen 1 isoform X2 [KO:K12478]
470919  RAB7A; ras-related protein Rab-7a [KO:K07897]
746637  CTSD; cathepsin D [KO:K01379] [EC:3.4.23.5]
454685  ATP6V0A1; V-type proton ATPase 116 kDa subunit a 1 isoform X2 [KO:K02154]
452354  ATP6V0A2; V-type proton ATPase 116 kDa subunit a 2 isoform X1 [KO:K02154]
463765  ATP6V0A4; V-type proton ATPase 116 kDa subunit a 4 isoform X1 [KO:K02154]
466895  TCIRG1; V-type proton ATPase 116 kDa subunit a 3 isoform X2 [KO:K02154]
472809  ATP6V0D2; V-type proton ATPase subunit d 2 [KO:K02146]
741872  ATP6V0D1; V-type proton ATPase subunit d 1 [KO:K02146]
740229  ATP6V1H; V-type proton ATPase subunit H isoform X1 [KO:K02144]
740281  ATP6AP1; V-type proton ATPase subunit S1 precursor [KO:K03662]
453837  ATP6V0C; V-type proton ATPase 16 kDa proteolipid subunit c isoform X1 [KO:K02155]
100610064  ATP6V0B; V-type proton ATPase 21 kDa proteolipid subunit c'' isoform X2 [KO:K03661]
737954  LAMP1; lysosome-associated membrane glycoprotein 1 precursor [KO:K06528]
737597  LAMP2; lysosome-associated membrane glycoprotein 2 isoform X1 [KO:K06528]
742406  PPP3CC; serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform isoform X4 [KO:K04348] [EC:3.1.3.16]
461403  PPP3CA; protein phosphatase 3 catalytic subunit alpha isoform X1 [KO:K04348] [EC:3.1.3.16]
450898  PPP3CB; serine/threonine-protein phosphatase 2B catalytic subunit beta isoform isoform X4 [KO:K04348] [EC:3.1.3.16]
736325  PPP3R2; calcineurin subunit B type 2 [KO:K06268]
100613118  PPP3R1; calcineurin subunit B type 1 isoform X2 [KO:K06268]
454038  CORO1A; coronin-1A [KO:K13882]
457259  FCGR1A; high affinity immunoglobulin gamma Fc receptor I isoform X2 [KO:K06498]
450194  FCGR2A; low affinity immunoglobulin gamma Fc region receptor II-a precursor [KO:K06472]
748765  low affinity immunoglobulin gamma Fc region receptor II-b isoform X1 [KO:K12560]
107973075  LOW QUALITY PROTEIN: low affinity immunoglobulin gamma Fc region receptor II-c [KO:K16824]
457457  FCGR3A; low affinity immunoglobulin gamma Fc region receptor III-A isoform X1 [KO:K06463]
745350  low affinity immunoglobulin gamma Fc region receptor III-B isoform X1 [KO:K06463]
Compound
C00076  Calcium cation
C00338  Lipopolysaccharide
C01194  1-Phosphatidyl-D-myo-inositol
C01561  Calcidiol
C01673  Calcitriol
C04549  1-Phosphatidyl-1D-myo-inositol 3-phosphate
C06124  Sphingosine 1-phosphate
C19190  Trehalose-6,6'-dibehenate
C21790  Mycobacterial trehalose dimycolate
G13101  Lipomannan
G13105  Triacylated phosphatidyl-myo-inositol pentamannoside
G13106  Triacylated phosphatidyl-myo-inositol hexamannoside
G13108  Triacylated phosphatidyl-myo-inositol dimannoside
G13109  Tetraacylated phosphatidyl-myo-inositol dimannoside
G13112  Tetraacylated phosphatidyl-myo-inositol hexamannoside
G13113  Tetraacylated phosphatidyl-myo-inositol pentamannoside
G13114  Lipoarabinomannan
G13115  Mannose-capped lipoarabinomannan
Reference
PMID:21274449
  Authors
Saiga H, Shimada Y, Takeda K
  Title
Innate immune effectors in mycobacterial infection.
  Journal
Clin Dev Immunol 2011:347594 (2011)
DOI:10.1155/2011/347594
Reference
PMID:20415982
  Authors
Dheda K, Schwander SK, Zhu B, van Zyl-Smit RN, Zhang Y
  Title
The immunology of tuberculosis: from bench to bedside.
  Journal
Respirology 15:433-50 (2010)
DOI:10.1111/j.1440-1843.2010.01739.x
Reference
PMID:11932234
  Authors
van Crevel R, Ottenhoff TH, van der Meer JW
  Title
Innate immunity to Mycobacterium tuberculosis.
  Journal
Clin Microbiol Rev 15:294-309 (2002)
DOI:10.1128/CMR.15.2.294-309.2002
Reference
PMID:18288961
  Authors
Torrelles JB, Azad AK, Henning LN, Carlson TK, Schlesinger LS
  Title
Role of C-type lectins in mycobacterial infections.
  Journal
Curr Drug Targets 9:102-12 (2008)
DOI:10.2174/138945008783502467
Reference
PMID:17359235
  Authors
Jo EK, Yang CS, Choi CH, Harding CV
  Title
Intracellular signalling cascades regulating innate immune responses to Mycobacteria: branching out from Toll-like receptors.
  Journal
Cell Microbiol 9:1087-98 (2007)
DOI:10.1111/j.1462-5822.2007.00914.x
Reference
PMID:21274433
  Authors
Marakalala MJ, Graham LM, Brown GD
  Title
The role of Syk/CARD9-coupled C-type lectin receptors in immunity to Mycobacterium tuberculosis infections.
  Journal
Clin Dev Immunol 2010:567571 (2010)
DOI:10.1155/2010/567571
Reference
PMID:15083155
  Authors
Koul A, Herget T, Klebl B, Ullrich A
  Title
Interplay between mycobacteria and host signalling pathways.
  Journal
Nat Rev Microbiol 2:189-202 (2004)
DOI:10.1038/nrmicro840
Reference
PMID:20199890
  Authors
Torrelles JB, Schlesinger LS
  Title
Diversity in Mycobacterium tuberculosis mannosylated cell wall determinants impacts adaptation to the host.
  Journal
Tuberculosis (Edinb) 90:84-93 (2010)
DOI:10.1016/j.tube.2010.02.003
Reference
PMID:15228522
  Authors
Briken V, Porcelli SA, Besra GS, Kremer L
  Title
Mycobacterial lipoarabinomannan and related lipoglycans: from biogenesis to modulation of the immune response.
  Journal
Mol Microbiol 53:391-403 (2004)
DOI:10.1111/j.1365-2958.2004.04183.x
Reference
PMID:19563525
  Authors
Baena A, Porcelli SA
  Title
Evasion and subversion of antigen presentation by Mycobacterium tuberculosis.
  Journal
Tissue Antigens 74:189-204 (2009)
DOI:10.1111/j.1399-0039.2009.01301.x
Reference
PMID:19369951
  Authors
Flannagan RS, Cosio G, Grinstein S
  Title
Antimicrobial mechanisms of phagocytes and bacterial evasion strategies.
  Journal
Nat Rev Microbiol 7:355-66 (2009)
DOI:10.1038/nrmicro2128
Reference
PMID:18541216
  Authors
Pieters J
  Title
Mycobacterium tuberculosis and the macrophage: maintaining a balance.
  Journal
Cell Host Microbe 3:399-407 (2008)
DOI:10.1016/j.chom.2008.05.006
Reference
PMID:19634703
  Authors
Scherr N, Jayachandran R, Mueller P, Pieters J
  Title
Interference of Mycobacterium tuberculosis with macrophage responses.
  Journal
Indian J Exp Biol 47:401-6 (2009)
Reference
PMID:16200082
  Authors
Reith W, LeibundGut-Landmann S, Waldburger JM.
  Title
Regulation of MHC class II gene expression by the class II transactivator.
  Journal
Nat Rev Immunol 5:793-806 (2005)
DOI:10.1038/nri1708
Reference
PMID:17785780
  Authors
Rothfuchs AG, Bafica A, Feng CG, Egen JG, Williams DL, Brown GD, Sher A
  Title
Dectin-1 interaction with Mycobacterium tuberculosis leads to enhanced IL-12p40 production by splenic dendritic cells.
  Journal
J Immunol 179:3463-71 (2007)
DOI:10.4049/jimmunol.179.6.3463
Reference
PMID:18407066
  Authors
Master SS, Rampini SK, Davis AS, Keller C, Ehlers S, Springer B, Timmins GS, Sander P, Deretic V
  Title
Mycobacterium tuberculosis prevents inflammasome activation.
  Journal
Cell Host Microbe 3:224-32 (2008)
DOI:10.1016/j.chom.2008.03.003
Reference
PMID:11378475
  Authors
Shtrichman R, Samuel CE
  Title
The role of gamma interferon in antimicrobial immunity.
  Journal
Curr Opin Microbiol 4:251-9 (2001)
DOI:10.1016/S1369-5274(00)00199-5
Related
pathway
ptr04010  MAPK signaling pathway
ptr04210  Apoptosis
ptr04612  Antigen processing and presentation
ptr04620  Toll-like receptor signaling pathway
ptr04621  NOD-like receptor signaling pathway
ptr04630  JAK-STAT signaling pathway
KO pathway
ko05152   
LinkDB

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