CHP2 activates the calcineurin/nuclear factor of activated T cells signaling pathway and enhances the oncogenic potential of HEK293 cells (Q24315700)

GOA release 2020-03-11

author name string

Guo-Dong Li

1

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Xi Zhang

2

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Rong Li

3

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Yue-Dan Wang

4

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Yan-Li Wang

5

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Ke-Jun Han

6

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Xiao-Ping Qian

7

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Cheng-Gang Yang

8

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Ping Liu

9

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Qun Wei

10

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Wei-Feng Chen

11

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Jun Zhang

12

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Yu Zhang

Journal of Biological Chemistry

13

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language of work or name

English

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publication date

21 November 2008

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published in

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volume

283

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issue

47

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page(s)

32660-8

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cites work

Calcineurin as a multifunctional regulator

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806684200

Transcriptional regulation by calcium, calcineurin, and NFAT

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806684200

NFAT proteins: key regulators of T-cell development and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806684200

An emerging role for Ca2+/calcineurin/NFAT signaling in cancerogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806684200

Transcription factor NFAT, its role in cancer development, and as a potential target for chemoprevention

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806684200

The calcineurin/NFAT signaling pathway: a novel therapeutic target in leukemia and solid tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806684200

Cabin 1, a negative regulator for calcineurin signaling in T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806684200

Cain, a novel physiologic protein inhibitor of calcineurin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806684200

AKAP79 inhibits calcineurin through a site distinct from the immunophilin-binding region

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806684200

Inherent calcineurin inhibitor FKBP38 targets Bcl-2 to mitochondria and inhibits apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806684200

Inhibition of calcineurin phosphatase activity by a calcineurin B homologous protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806684200

Characterization of tescalcin, a novel EF-hand protein with a single Ca2+-binding site: metal-binding properties, localization in tissues and cells, and effect on calcineurin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806684200

Calcineurin homologous protein as an essential cofactor for Na+/H+ exchangers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806684200

The EF-hand Ca2+-binding protein p22 plays a role in microtubule and endoplasmic reticulum organization and dynamics with distinct Ca2+-binding requirements

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806684200

Calcineurin B homologous protein 3 promotes the biosynthetic maturation, cell surface stability, and optimal transport of the Na+/H+ exchanger NHE1 isoform

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806684200

Large scale identification of human hepatocellular carcinoma-associated antigens by autoantibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806684200

Expression of calcineurin B homologous protein 2 protects serum deprivation-induced cell death by serum-independent activation of Na+/H+ exchanger

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806684200

Preparation and characterization of a single-chain calcineurin-calmodulin complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806684200

Non-catalytic domains of subunit A negatively regulate the activity of calcineurin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806684200

Regulation of cell cycle progression by calcium/calmodulin-dependent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806684200

Direct comparison of Ca2+ requirements for calmodulin interaction with and activation of protein phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806684200

Calcium regulation of calcineurin phosphatase activity by its B subunit and calmodulin. Role of the autoinhibitory domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806684200

A serine/threonine kinase which causes apoptosis-like cell death interacts with a calcineurin B-like protein capable of binding Na(+)/H(+) exchanger

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806684200

The apoptosis-inducing protein kinase DRAK2 is inhibited in a calcium-dependent manner by the calcium-binding protein CHP

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806684200

Targeting calcineurin activation as a therapeutic strategy for T-cell acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806684200

Overexpression of c-myc in pancreatic cancer caused by ectopic activation of NFATc1 and the Ca2+/calcineurin signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806684200

A constitutively active NFATc1 mutant induces a transformed phenotype in 3T3-L1 fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806684200

The role of NFAT transcription factors in integrin-mediated carcinoma invasion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806684200

A tumor-suppressor function for NFATc3 in T-cell lymphomagenesis by murine leukemia virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806684200

Targeted deletion of the calcineurin inhibitor DSCR1 suppresses tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806684200

Overexpression of calcineurin B subunit (CnB) enhances the oncogenic potential of HEK293 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806684200

Increased expression of calcineurin in human colorectal adenocarcinomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806684200

7 January 2021

The threshold pattern of calcineurin-dependent gene expression is altered by loss of the endogenous inhibitor calcipressin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806684200

7 January 2021

The NFATc1 transcription factor is widely expressed in white cells and translocates from the cytoplasm to the nucleus in a subset of human lymphomas

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806684200

7 January 2021

Calcineurin: form and function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M806684200

7 January 2021