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Bovine viral diarrhea virus NS3 serine proteinase: polyprotein cleavage sites, cofactor requirements, and molecular model of an enzyme essential for pestivirus replication - Wikidata

Bovine viral diarrhea virus NS3 serine proteinase: polyprotein cleavage sites, cofactor requirements, and molecular model of an enzyme essential for pestivirus replication (Q27480836)

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English	Bovine viral diarrhea virus NS3 serine proteinase: polyprotein cleavage sites, cofactor requirements, and molecular model of an enzyme essential for pestivirus replication	scientific article

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3 November 2019

Bovine viral diarrhea virus NS3 serine proteinase: polyprotein cleavage sites, cofactor requirements, and molecular model of an enzyme essential for pestivirus replication (English)

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3 November 2019

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Charles M. Rice

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C M Rice

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3 November 2019

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J Xu

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3 November 2019

E Mendez

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P R Caron

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C Lin

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M A Murcko

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M S Collett

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1 July 1997

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3 November 2019

Journal of Virology

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3 November 2019

71

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3 November 2019

7

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3 November 2019

5312-5322

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3 November 2019

Authentic and chimeric full-length genomic cDNA clones of bovine viral diarrhea virus that yield infectious transcripts

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20 March 2017

Internal entry of ribosomes is directed by the 5' noncoding region of classical swine fever virus and is dependent on the presence of an RNA pseudoknot upstream of the initiation codon

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20 March 2017

Recovery of cytopathogenic and noncytopathogenic bovine viral diarrhea viruses from cDNA constructs

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20 March 2017

Cytopathogenicity of a pestivirus correlates with a 27-nucleotide insertion

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20 March 2017

Crystal structure of the hepatitis C virus NS3 protease domain complexed with a synthetic NS4A cofactor peptide

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20 March 2017

The crystal structure of hepatitis C virus NS3 proteinase reveals a trypsin-like fold and a structural zinc binding site

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20 March 2017

Activity of purified hepatitis C virus protease NS3 on peptide substrates

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20 March 2017

Processing in the pestivirus E2-NS2 region: identification of proteins p7 and E2p7

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20 March 2017

Nucleotide sequence of classical swine fever virus strain Alfort/187 and transcription of infectious RNA from stably cloned full-length cDNA

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20 March 2017

Classical swine fever virus: recovery of infectious viruses from cDNA constructs and generation of recombinant cytopathogenic defective interfering particles

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20 March 2017

Infectious RNA transcribed from an engineered full-length cDNA template of the genome of a pestivirus

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20 March 2017

Identification of the sequence on NS4A required for enhanced cleavage of the NS5A/5B site by hepatitis C virus NS3 protease

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20 March 2017

Cleavage at a novel site in the NS4A region by the yellow fever virus NS2B-3 proteinase is a prerequisite for processing at the downstream 4A/4B signalase site

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20 March 2017

Mutagenesis of the yellow fever virus NS2B protein: effects on proteolytic processing, NS2B-NS3 complex formation, and viral replication

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20 March 2017

Two distinct proteinase activities required for the processing of a putative nonstructural precursor protein of hepatitis C virus

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20 March 2017

Processing of the envelope glycoproteins of pestiviruses

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20 March 2017

Characterization of the hepatitis C virus-encoded serine proteinase: determination of proteinase-dependent polyprotein cleavage sites

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20 March 2017

Deletion analysis of dengue virus type 4 nonstructural protein NS2B: identification of a domain required for NS2B-NS3 protease activity

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20 March 2017

Processing of pestivirus polyprotein: cleavage site between autoprotease and nucleocapsid protein of classical swine fever virus

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20 March 2017

NS2B-3 proteinase-mediated processing in the yellow fever virus structural region: in vitro and in vivo studies

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20 March 2017

Both NS3 and NS4A are required for proteolytic processing of hepatitis C virus nonstructural proteins

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20 March 2017

Two hepatitis C virus glycoprotein E2 products with different C termini

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20 March 2017

Kinetic and structural analyses of hepatitis C virus polyprotein processing

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20 March 2017

Substrate determinants for cleavage in cis and in trans by the hepatitis C virus NS3 proteinase

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20 March 2017

Hepatitis C virus NS3 serine proteinase: trans-cleavage requirements and processing kinetics

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20 March 2017

Specificity of the hepatitis C virus NS3 serine protease: effects of substitutions at the 3/4A, 4A/4B, 4B/5A, and 5A/5B cleavage sites on polyprotein processing

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20 March 2017

Substrate requirements of hepatitis C virus serine proteinase for intermolecular polypeptide cleavage in Escherichia coli

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20 March 2017

An amino-terminal domain of the hepatitis C virus NS3 protease is essential for interaction with NS4A

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20 March 2017

Pestivirus NS3 (p80) protein possesses RNA helicase activity

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20 March 2017

Mutagenesis of the yellow fever virus NS2B/3 cleavage site: determinants of cleavage site specificity and effects on polyprotein processing and viral replication

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20 March 2017

Hepatitis C virus-encoded nonstructural protein NS4A has versatile functions in viral protein processing

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20 March 2017

A central region in the hepatitis C virus NS4A protein allows formation of an active NS3-NS4A serine proteinase complex in vivo and in vitro

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20 March 2017

The N-terminal region of hepatitis C virus nonstructural protein 3 (NS3) is essential for stable complex formation with NS4A

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20 March 2017

Hepatitis C virus-encoded NS2-3 protease: cleavage-site mutagenesis and requirements for bimolecular cleavage

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20 March 2017

Phosphorylation of hepatitis C virus-encoded nonstructural protein NS5A

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20 March 2017

Processing in the hepatitis C virus E2-NS2 region: identification of p7 and two distinct E2-specific products with different C termini

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20 March 2017

Complex formation between the NS3 serine-type proteinase of the hepatitis C virus and NS4A and its importance for polyprotein maturation

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Structures of product and inhibitor complexes of Streptomyces griseus protease A at 1.8 A resolution. A model for serine protease catalysis

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Production of infectious RNA transcripts from Sindbis virus cDNA clones: mapping of lethal mutations, rescue of a temperature-sensitive marker, and in vitro mutagenesis to generate defined mutants

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Flavivirus genome organization, expression, and replication

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20 March 2017

Both nonstructural proteins NS2B and NS3 are required for the proteolytic processing of dengue virus nonstructural proteins

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20 March 2017

Processing of the yellow fever virus nonstructural polyprotein: a catalytically active NS3 proteinase domain and NS2B are required for cleavages at dibasic sites

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20 March 2017

Pestivirus gene expression: the first protein product of the bovine viral diarrhea virus large open reading frame, p20, possesses proteolytic activity

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20 March 2017

A simple method for displaying the hydropathic character of a protein

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20 March 2017

On the size of the active site in proteases. I. Papain

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Eukaryotic transient-expression system based on recombinant vaccinia virus that synthesizes bacteriophage T7 RNA polymerase

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20 March 2017

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20 March 2017

Sequence from picomole quantities of proteins electroblotted onto polyvinylidene difluoride membranes

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20 March 2017

Recombinant dengue type 1 virus NS5 protein expressed in Escherichia coli exhibits RNA-dependent RNA polymerase activity

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20 March 2017

Molecular characterization of pestiviruses

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7 April 2017

Identification and properties of the RNA-dependent RNA polymerase of hepatitis C virus

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7 April 2017

A second hepatitis C virus-encoded proteinase

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7 April 2017

Structural basis of substrate specificity in the serine proteases

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7 April 2017

Association between NS3 and NS5 Proteins of Dengue Virus Type 2 in the Putative RNA Replicase Is Linked to Differential Phosphorylation of NS5

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7 April 2017

Proteins encoded by bovine viral diarrhea virus: the genomic organization of a pestivirus

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7 April 2017

Molecular cloning and nucleotide sequence of the pestivirus bovine viral diarrhea virus

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7 April 2017

Molecular cloning and nucleotide sequence of the genome of hog cholera virus

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7 April 2017

Detection of a trypsin-like serine protease domain in flaviviruses and pestiviruses

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7 April 2017

N-terminal domains of putative helicases of flavi- and pestiviruses may be serine proteases

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7 April 2017

Transcription of infectious yellow fever RNA from full-length cDNA templates produced by in vitro ligation

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7 April 2017

Product review. New mammalian expression vectors

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7 April 2017

Evidence that the N-terminal domain of nonstructural protein NS3 from yellow fever virus is a serine protease responsible for site-specific cleavages in the viral polyprotein

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7 April 2017

Pestivirus gene expression: Protein p80 of bovine viral diarrhea virus is a proteinase involved in polyprotein processing

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7 April 2017

Dengue 2 virus NS2B and NS3 form a stable complex that can cleave NS3 within the helicase domain

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29 September 2017

5' and 3' untranslated regions of pestivirus genome: primary and secondary structure analyses

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29 September 2017

Molecular model of the specificity pocket of the hepatitis C virus protease: implications for substrate recognition.

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29 September 2017

Mutagenesis of the yellow fever virus NS2A/2B cleavage site: effects on proteolytic processing, viral replication, and evidence for alternative processing of the NS2A protein

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29 September 2017

The hepatitis C virus NS3 serine proteinase and NS4A cofactor: establishment of a cell-free trans-processing assay

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29 September 2017

Yellow fever virus proteins NS2A, NS2B, and NS4B: identification and partial N-terminal amino acid sequence analysis

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29 September 2017

The Pestiviruses

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29 September 2017

Vaccinia Virus Replication I. Requirement for the Host-Cell Nucleus

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29 September 2017

Bovine viral diarrhea virus genomic organization

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2 June 2018

Enhancement of hepatitis C virus NS3 proteinase activity by association with NS4A-specific synthetic peptides: identification of sequence and critical residues of NS4A for the cofactor activity

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2 June 2018

RNA-stimulated NTPase activity associated with the p80 protein of the pestivirus bovine viral diarrhea virus

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2 June 2018

Complex processing and protein:protein interactions in the E2:NS2 region of HCV.

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2 June 2018

Pestivirus translation initiation occurs by internal ribosome entry

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2 June 2018

Engineering proteases with altered specificity

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191768

2 June 2018

Molecular cloning and nucleotide sequence of hog cholera virus strain Brescia and mapping of the genomic region encoding envelope protein E1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191768

2 June 2018

Converting trypsin to chymotrypsin: the role of surface loops

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191768

2 June 2018

Molecular cloning and nucleotide sequence of a pestivirus genome, noncytopathic bovine viral diarrhea virus strain SD-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191768

2 June 2018

Rearrangement of viral sequences in cytopathogenic pestiviruses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191768

2 June 2018

Baculovirus expression of pestivirus non-structural proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191768

2 June 2018

Selective alteration of substrate specificity by replacement of aspartic acid-189 with lysine in the binding pocket of trypsin.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191768

19 June 2018

Redesigning the substrate specificity of the hepatitis C virus NS3 protease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191768

27 November 2018

A central hydrophobic domain of the hepatitis C virus NS4A protein is necessary and sufficient for the activation of the NS3 protease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191768

27 November 2018

Nucleotide sequence of the bovine viral diarrhoea virus Osloss strain: comparison with related viruses and identification of specific DNA probes in the 5' untranslated region

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191768

27 November 2018

Substrate specificity of the NS3 serine proteinase of hepatitis C virus as determined by mutagenesis at the NS3/NS4A junction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191768

27 November 2018

The genomic sequence of a virulent bovine viral diarrhea virus (BVDV) from the type 2 genotype: detection of a large genomic insertion in a noncytopathic BVDV.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191768

27 November 2018

Comparative modeling methods: application to the family of the mammalian serine proteases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191768

27 November 2018

Association of sindbis virion glycoproteins and their precursors

1 reference

https://pubmed.ncbi.nlm.nih.gov/9188600

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9188600%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9188600%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

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