Crystal structure of opsin in its G-protein-interacting conformation (Q27652301)

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14 January 2020

title

Crystal structure of opsin in its G-protein-interacting conformation (English)

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14 January 2020

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1

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14 January 2020

Norbert Krauß

5

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14 January 2020

Oliver Ernst

8

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14 January 2020

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Klaus Peter Hofmann

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14 January 2020

author name string

Jung Hee Park

2

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14 January 2020

Peter W Hildebrand

3

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14 January 2020

Yong Ju Kim

4

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14 January 2020

Hui-Woog Choe

6

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14 January 2020

language of work or name

English

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publication date

1 September 2008

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14 January 2020

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14 January 2020

volume

455

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14 January 2020

issue

7212

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14 January 2020

page(s)

497-502

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Seven-transmembrane receptors

14 January 2020

cites work

1 reference

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7 January 2021

Structural diversity of G protein-coupled receptors and significance for drug discovery

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Activation of rhodopsin: new insights from structural and biochemical studies

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7 January 2021

Sequence of late molecular events in the activation of rhodopsin

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7 January 2021

Dark adaptation and the retinoid cycle of vision

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7 January 2021

Conformations of the active and inactive states of opsin

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7 January 2021

Crystal structure of rhodopsin: A G protein-coupled receptor

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7 January 2021

Structure of bovine rhodopsin in a trigonal crystal form.

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7 January 2021

The retinal conformation and its environment in rhodopsin in light of a new 2.2 A crystal structure

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7 January 2021

Crystal structure of squid rhodopsin

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7 January 2021

Local peptide movement in the photoreaction intermediate of rhodopsin

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7 January 2021

Crystal structure of a photoactivated deprotonated intermediate of rhodopsin

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7 January 2021

Structure of a beta1-adrenergic G-protein-coupled receptor

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7 January 2021

High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor

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7 January 2021

Requirement of rigid-body motion of transmembrane helices for light activation of rhodopsin

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7 January 2021

Rhodopsin activation blocked by metal-ion-binding sites linking transmembrane helices C and F.

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7 January 2021

High-resolution distance mapping in rhodopsin reveals the pattern of helix movement due to activation

1 reference

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7 January 2021

Crystal structure of the ligand-free G-protein-coupled receptor opsin

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7 January 2021

Role of the conserved NPxxY(x)5,6F motif in the rhodopsin ground state and during activation

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7 January 2021

Site of G protein binding to rhodopsin mapped with synthetic peptides from the alpha subunit

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7 January 2021

Heterotrimeric G protein activation by G-protein-coupled receptors

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7 January 2021

Sequence of interactions in receptor-G protein coupling.

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7 January 2021

Light-activated rhodopsin induces structural binding motif in G protein alpha subunit

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7 January 2021

Structure and orientation of a G protein fragment in the receptor bound state from residual dipolar couplings

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7 January 2021

Two different forms of metarhodopsin II: Schiff base deprotonation precedes proton uptake and signaling state

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7 January 2021

Transducin-alpha C-terminal peptide binding site consists of C-D and E-F loops of rhodopsin

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7 January 2021

Rhodopsin activation exposes a key hydrophobic binding site for the transducin alpha-subunit C terminus

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7 January 2021

Mapping of contact sites in complex formation between transducin and light-activated rhodopsin by covalent crosslinking: use of a photoactivatable reagent

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7 January 2021

The 2.0 A crystal structure of a heterotrimeric G protein

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7 January 2021

Conformational changes associated with receptor-stimulated guanine nucleotide exchange in a heterotrimeric G-protein alpha-subunit: NMR analysis of GTPgammaS-bound states

1 reference

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7 January 2021

Mutation of the fourth cytoplasmic loop of rhodopsin affects binding of transducin and peptides derived from the carboxyl-terminal sequences of transducin alpha and gamma subunits.

1 reference

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7 January 2021

Pivotal role of the glycine-rich TM3 helix in gating the MscS mechanosensitive channel.

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7 January 2021

Hydrogen-bonding and packing features of membrane proteins: functional implications

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7 January 2021

Mechanism of activation and inactivation of opsin: role of Glu113 and Lys296

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7 January 2021

Regulation of the rhodopsin-transducin interaction by a highly conserved carboxylic acid group

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7 January 2021

Rhodopsin mutants that bind but fail to activate transducin

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7 January 2021

Building functional modules from molecular interactions

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7 January 2021

Signaling states of rhodopsin. Retinal provides a scaffold for activating proton transfer switches.

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7 January 2021

Role of noncovalent binding of 11-cis-retinal to opsin in dark adaptation of rod and cone photoreceptors

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7 January 2021

Mechanism of the receptor-catalyzed activation of heterotrimeric G proteins

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7 January 2021

Probing the mechanism of rhodopsin-catalyzed transducin activation.

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7 January 2021

Disruption of the alpha5 helix of transducin impairs rhodopsin-catalyzed nucleotide exchange

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7 January 2021

Signal transfer from GPCRs to G proteins: role of the G alpha N-terminal region in rhodopsin-transducin coupling.

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7 January 2021

The carboxyl terminus of the Galpha-subunit is the latch for triggered activation of heterotrimeric G proteins

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7 January 2021

RETRACTED: Structural basis for nucleotide exchange on G alpha i subunits and receptor coupling specificity

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7 January 2021

Maximal rate and nucleotide dependence of rhodopsin-catalyzed transducin activation: initial rate analysis based on a double displacement mechanism

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7 January 2021

Rhodopsin-transducin coupling: role of the Galpha C-terminus in nucleotide exchange catalysis.

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7 January 2021

Assays for activation of opsin by all-trans-retinal

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7 January 2021

Crystallization and crystal properties of squid rhodopsin

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7 January 2021

Processing of X-ray diffraction data collected in oscillation mode

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7 January 2021

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7 January 2021

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7 January 2021

Errors in protein structures

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7 January 2021

Satisfying hydrogen bonding potential in proteins

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7 January 2021

Identifiers

DOI

10.1038/NATURE07330

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18818650%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

14 January 2020

1045334162

0 references

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017