Inflammation and cellular stress: a mechanistic link between immune-mediated and metabolically driven pathologies (Q28236897)

European Journal of Nutrition

Europe PubMed Central

title

Inflammation and cellular stress: a mechanistic link between immune-mediated and metabolically driven pathologies (English)

0 references

0 references

0 references

Eva Rath

1

0 references

Dirk Haller

series ordinal

2

0 references

language of work or name

English

0 references

publication date

June 2011

0 references

published in

0 references

volume

50

0 references

issue

4

0 references

page(s)

219-33

0 references

cites work

Obesity and diabetes in the developing world--a growing challenge

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Mechanisms of Disease: pathogenesis of Crohn's disease and ulcerative colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Distribution of major health risks: findings from the Global Burden of Disease study

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Inflammation and metabolic disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

The role of the unfolded protein response in tumour development: friend or foe?

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

From endoplasmic-reticulum stress to the inflammatory response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Signal integration in the endoplasmic reticulum unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

The mammalian unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Mediators of endoplasmic reticulum stress-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Increased sensitivity to dextran sodium sulfate colitis in IRE1beta-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Translational repression mediates activation of nuclear factor kappa B by phosphorylated translation initiation factor 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Coupling endoplasmic reticulum stress to the cell death program

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Induction of two transformation-sensitive membrane polypeptides in normal fibroblasts by a block in glycoprotein synthesis or glucose deprivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Endoplasmic reticulum stress and the inflammatory basis of metabolic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Translational control is required for the unfolded protein response and in vivo glucose homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Mitochondria-endoplasmic reticulum choreography: structure and signaling dynamics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Coupling mitochondrial dysfunction to endoplasmic reticulum stress response: a molecular mechanism leading to hepatic insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Paradoxical decrease of mitochondrial DNA deletions in epithelial cells of active ulcerative colitis patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

ER-mediated stress induces mitochondrial-dependent caspases activation in NT2 neuron-like cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

The luminal domain of ATF6 senses endoplasmic reticulum (ER) stress and causes translocation of ATF6 from the ER to the Golgi

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

The transmembrane kinase Ire1p is a site-specific endonuclease that initiates mRNA splicing in the unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

XBP-1 Regulates a Subset of Endoplasmic Reticulum Resident Chaperone Genes in the Unfolded Protein Response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

XBP1: a link between the unfolded protein response, lipid biosynthesis, and biogenesis of the endoplasmic reticulum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Regulated Ire1-dependent decay of messenger RNAs in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Identification of the cis-acting endoplasmic reticulum stress response element responsible for transcriptional induction of mammalian glucose-regulated proteins. Involvement of basic leucine zipper transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Identification of ERSE-II, a new cis-acting element responsible for the ATF6-dependent mammalian unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

ATF6alpha induces XBP1-independent expansion of the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Transmembrane bZIP transcription factors in ER stress signaling and the unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Signalling mediated by the endoplasmic reticulum stress transducer OASIS is involved in bone formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

ATF6alpha optimizes long-term endoplasmic reticulum function to protect cells from chronic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Perk is essential for translational regulation and cell survival during the unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Growth arrest and DNA damage-inducible protein GADD34 assembles a novel signaling complex containing protein phosphatase 1 and inhibitor 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Growth arrest and DNA damage-inducible protein GADD34 targets protein phosphatase 1 alpha to the endoplasmic reticulum and promotes dephosphorylation of the alpha subunit of eukaryotic translation initiation factor 2

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Coordination of ER and oxidative stress signaling: the PERK/Nrf2 signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Nrf2 Is a Direct PERK Substrate and Effector of PERK-Dependent Cell Survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Impact of protein kinase PKR in cell biology: from antiviral to antiproliferative action

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Nck-dependent activation of extracellular signal-regulated kinase-1 and regulation of cell survival during endoplasmic reticulum stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Plasma cell differentiation and the unfolded protein response intersect at the transcription factor XBP-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Plasma cell differentiation requires the transcription factor XBP-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Activation of the Akt-NF-kappaB pathway by subtilase cytotoxin through the ATF6 branch of the unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Phosphorylation of the alpha subunit of eukaryotic initiation factor 2 is required for activation of NF-kappaB in response to diverse cellular stresses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Free cholesterol-loaded macrophages are an abundant source of tumor necrosis factor-alpha and interleukin-6: model of NF-kappaB- and map kinase-dependent inflammation in advanced atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Hypothalamic IKKbeta/NF-kappaB and ER stress link overnutrition to energy imbalance and obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

S-nitrosylated protein-disulphide isomerase links protein misfolding to neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Adaptive suppression of the ATF4-CHOP branch of the unfolded protein response by toll-like receptor signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Loss of Toll-like receptor 2 and 4 leads to differential induction of endoplasmic reticulum stress and proapoptotic responses in the intestinal epithelium under conditions of chronic inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Connecting endoplasmic reticulum stress to autophagy by unfolded protein response and calcium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Lysosomes and autophagy in cell death control

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Self-eating and self-killing: crosstalk between autophagy and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Autophagy is activated for cell survival after endoplasmic reticulum stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Autophagy counterbalances endoplasmic reticulum expansion during the unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

ER stress (PERK/eIF2alpha phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Two endoplasmic reticulum-associated degradation (ERAD) systems for the novel variant of the mutant dysferlin: ubiquitin/proteasome ERAD(I) and autophagy/lysosome ERAD(II).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Regulation of autophagy by ROS: physiology and pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Ubiquitous calpains promote caspase-12 and JNK activation during endoplasmic reticulum stress-induced apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

An endoplasmic reticulum stress-specific caspase cascade in apoptosis. Cytochrome c-independent activation of caspase-9 by caspase-12

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Coupling endoplasmic reticulum stress to the cell death program. An Apaf-1-independent intrinsic pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Human caspase 12 has acquired deleterious mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Involvement of caspase-4 in endoplasmic reticulum stress-induced apoptosis and Abeta-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Complexes containing activating transcription factor (ATF)/cAMP-responsive-element-binding protein (CREB) interact with the CCAAT/enhancer-binding protein (C/EBP)-ATF composite site to regulate Gadd153 expression during the stress response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Divergent effects of PERK and IRE1 signaling on cell viability

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Regulated translation initiation controls stress-induced gene expression in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

ER stress triggers apoptosis by activating BH3-only protein Bim

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Role of SERCA1 truncated isoform in the proapoptotic calcium transfer from ER to mitochondria during ER stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

IRE1 signaling affects cell fate during the unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

BAX and BAK regulation of endoplasmic reticulum Ca2+: a control point for apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Bax and Bak can localize to the endoplasmic reticulum to initiate apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

XBP1 controls diverse cell type- and condition-specific transcriptional regulatory networks

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Translation attenuation through eIF2alpha phosphorylation prevents oxidative stress and maintains the differentiated state in beta cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

HMG-CoA reductase inhibitors activate the unfolded protein response and induce cytoprotective GRP78 expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

A proposed model of fat packaging by exchangeable lipid droplet proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Regulation of hepatic lipogenesis by the transcription factor XBP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

PERK-dependent regulation of lipogenesis during mouse mammary gland development and adipocyte differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

UPR pathways combine to prevent hepatic steatosis caused by ER stress-mediated suppression of transcriptional master regulators.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Metabolic response of mice to a postnatal ablation of CCAAT/enhancer-binding protein alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Increased hepatic cell proliferation and lung abnormalities in mice deficient in CCAAT/enhancer binding protein alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Impaired Energy Homeostasis in C/EBPαあるふぁ Knockout Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Transmission of cell stress from endoplasmic reticulum to mitochondria: enhanced expression of Lon protease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Discovery of genes activated by the mitochondrial unfolded protein response (mtUPR) and cognate promoter elements

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

A mitochondrial specific stress response in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

The chop gene contains an element for the positive regulation of the mitochondrial unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Mitochondrial-nuclear communications

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

The matrix peptide exporter HAF-1 signals a mitochondrial UPR by activating the transcription factor ZC376.7 in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

ClpP mediates activation of a mitochondrial unfolded protein response in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Antifolding activity of hsp60 couples protein import into the mitochondrial matrix with export to the intermembrane space

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Double-stranded RNA-dependent protein kinase links pathogen sensing with stress and metabolic homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Impairment of the ubiquitin-proteasome system by protein aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Defective intracellular transport is the molecular basis of rhodopsin-dependent dominant retinal degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

The unfolded protein response: a novel component of the hypoxic stress response in tumors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Activating transcription factor 4 is translationally regulated by hypoxic stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

XBP1 is essential for survival under hypoxic conditions and is required for tumor growth.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

The differentiation and stress response factor XBP-1 drives multiple myeloma pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Reducing endoplasmic reticulum stress through a macrophage lipid chaperone alleviates atherosclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Induction of endoplasmic reticulum stress-induced beta-cell apoptosis and accumulation of polyubiquitinated proteins by human islet amyloid polypeptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Free fatty acids and cytokines induce pancreatic beta-cell apoptosis by different mechanisms: role of nuclear factor-kappaB and endoplasmic reticulum stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Disruption of endoplasmic reticulum structure and integrity in lipotoxic cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Obesity, Inflammation, and Insulin Resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Diabetes mellitus and exocrine pancreatic dysfunction in perk-/- mice reveals a role for translational control in secretory cell survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

EIF2AK3, encoding translation initiation factor 2-alpha kinase 3, is mutated in patients with Wolcott-Rallison syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

The regulatory subunits of PI3K, p85alpha and p85beta, interact with XBP-1 and increase its nuclear translocation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

A regulatory subunit of phosphoinositide 3-kinase increases the nuclear accumulation of X-box-binding protein-1 to modulate the unfolded protein response

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Regulation of glucose homeostasis through a XBP-1-FoxO1 interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

The endoplasmic reticulum chaperone improves insulin resistance in type 2 diabetes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Involvement of endoplasmic reticulum stress in insulin resistance and diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Mature-onset obesity and insulin resistance in mice deficient in the signaling adapter p62.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Autophagy is important in islet homeostasis and compensatory increase of beta cell mass in response to high-fat diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Loss of autophagy diminishes pancreatic beta cell mass and function with resultant hyperglycemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Mitochondrial function is required for secretion of DAF-28/insulin in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Bacteria- and host-derived mechanisms to control intestinal epithelial cell homeostasis: implications for chronic inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Interleukin-10 blocked endoplasmic reticulum stress in intestinal epithelial cells: impact on chronic inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Deficient host-bacteria interactions in inflammatory bowel disease? The toll-like receptor (TLR)-4 Asp299gly polymorphism is associated with Crohn's disease and ulcerative colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Reduced Paneth cell alpha-defensins in ileal Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Paneth cells and inflammation dance together in Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Depletion of luminal iron alters the gut microbiota and prevents Crohn's disease-like ileitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

ER stress controls iron metabolism through induction of hepcidin

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Mitochondrial dysfunction, persistent oxidative damage, and catalase inhibition in immune cells of naïve and treated Crohn's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Clostridium difficile toxin A triggers human colonocyte IL-8 release via mitochondrial oxygen radical generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Interleukin 10 inhibits interferon gamma- and tumor necrosis factor alpha-stimulated activation of NADPH oxidase 1 in human colonic epithelial cells and the mouse colon

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Enhanced translocation of bacteria across metabolically stressed epithelia is reduced by butyrate

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Epithelia under metabolic stress perceive commensal bacteria as a threat

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Augmented increase in tight junction permeability by luminal stimuli in the non-inflamed ileum of Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Transepithelial transport processes at the intestinal mucosa in inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Salicylates trigger protein synthesis inhibition in a protein kinase R-like endoplasmic reticulum kinase-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Inhibition of apolipoprotein B100 secretion by lipid-induced hepatic endoplasmic reticulum stress in rodents

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Endoplasmic reticulum stress inhibition protects against excitotoxic neuronal injury in the rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Mitochondrion-specific antioxidants as drug treatments for Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00394-011-0197-0

Anticancer effects of thiazolidinediones are independent of peroxisome proliferator-activated receptor gamma and mediated by inhibition of translation initiation.

21 January 2018

1 reference

12 December 2020

Toll-like receptor 2 is protective of ischemia-reperfusion-mediated small-bowel injury in a murine model

1 reference

12 December 2020

Adenylate Kinase 2 Links Mitochondrial Energy Metabolism to the Induction of the Unfolded Protein Response

1 reference

12 December 2020

The double-strand RNA-dependent protein kinase PKR plays a significant role in a sustained ER stress-induced apoptosis

1 reference

12 December 2020

Mitochondria regulate the unfolded protein response leading to cancer cell survival under glucose deprivation conditions

1 reference

12 December 2020

Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6alpha and XBP1

1 reference

12 December 2020

Genetic deletion of PKR abrogates TNF-induced activation of IkappaBalpha kinase, JNK, Akt and cell proliferation but potentiates p44/p42 MAPK and p38 MAPK activation

1 reference

12 December 2020

Two distinct stress signaling pathways converge upon the CHOP promoter during the mammalian unfolded protein response

1 reference

12 December 2020

Dysfunctional mitochondria contain endogenous high-affinity human Toll-like receptor 4 (TLR4) ligands and induce TLR4-mediated inflammatory reactions.

1 reference

12 December 2020

Gene-environment interactions in chronic inflammatory disease

1 reference

12 December 2020

Obesity and socioeconomic status in children and adolescents: United States, 2005-2008.

1 reference

12 December 2020

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

1 reference

12 December 2020

Thematic review series: Adipocyte Biology. Adipocyte stress: the endoplasmic reticulum and metabolic disease

1 reference

12 December 2020

The CREB coactivator CRTC2 links hepatic ER stress and fasting gluconeogenesis

1 reference

12 December 2020

Degradation of misfolded proteins prevents ER-derived oxidative stress and cell death

1 reference

12 December 2020

10.1007/S00394-011-0197-0

Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

21547407

1 reference

Consolidated OpenCitations Corpus – April 2017