A GREM1 gene variant associates with diabetic nephropathy (Q33834265)

29 July 2017

title

A GREM1 gene variant associates with diabetic nephropathy (English)

1 reference

29 July 2017

Amy Jayne McKnight

1

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Peter Maxwell

object named as

Alexander P Maxwell

8

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Kerry Pettigrew

1 reference

ORCID Public Data File 2021

author name string

Christopher C Patterson

2

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29 July 2017

Kerry A Pettigrew

3

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29 July 2017

David A Savage

4

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29 July 2017

Jill Kilner

5

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29 July 2017

Madeline Murphy

6

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29 July 2017

Denise Sadlier

7

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29 July 2017

Warren 3/U.K. Genetics of Kidneys in Diabetes (GoKinD) Study Group

9

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29 July 2017

publication date

11 February 2010

1 reference

Journal of the American Society of Nephrology

29 July 2017

published in

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29 July 2017

volume

21

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29 July 2017

issue

5

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29 July 2017

page(s)

773-781

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Evaluation of gremlin 1 (GREM1) as a candidate susceptibility gene for albuminuria-related traits in Mexican Americans with type 2 diabetes mellitus

29 July 2017

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Allelic depletion of grem1 attenuates diabetic kidney disease

4 July 2018

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Genetic analysis of coronary artery disease single-nucleotide polymorphisms in diabetic nephropathy

4 July 2018

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Bone morphogenetic protein-7 and Gremlin: New emerging therapeutic targets for diabetic nephropathy

4 July 2018

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4 July 2018

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4 July 2018

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Exclusion of polymorphisms in carnosinase genes (CNDP1 and CNDP2) as a cause of diabetic nephropathy in type 1 diabetes: results of large case-control and follow-up studies

4 July 2018

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Notch receptors: a new target in glomerular diseases

4 July 2018

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Gremlin: a novel mediator of epithelial mesenchymal transition and fibrosis in chronic allograft nephropathy.

4 July 2018

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4 July 2018

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4 July 2018

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Co-regulation of Gremlin and Notch signalling in diabetic nephropathy

4 July 2018

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4 July 2018

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4 July 2018

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Modulator of bone morphogenetic protein activity in the progression of kidney diseases

4 July 2018

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The bone morphogenetic protein antagonist gremlin 1 is overexpressed in human cancers and interacts with YWHAH protein

4 July 2018

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DNA methylation-associated inactivation of TGFbeta-related genes DRM/Gremlin, RUNX3, and HPP1 in human cancers

4 July 2018

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4 July 2018

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Gremlin-mediated BMP antagonism induces the epithelial-mesenchymal feedback signaling controlling metanephric kidney and limb organogenesis

4 July 2018

1 reference

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Mouse limb deformity mutations disrupt a global control region within the large regulatory landscape required for Gremlin expression

4 July 2018

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4 July 2018

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Gremlin is the BMP antagonist required for maintenance of Shh and Fgf signals during limb patterning

4 July 2018

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4 July 2018

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Micro RNAs are complementary to 3' UTR sequence motifs that mediate negative post-transcriptional regulation

4 July 2018

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Loss of tubular bone morphogenetic protein-7 in diabetic nephropathy

4 July 2018

1 reference

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A family-based strategy to identify genes for diabetic nephropathy.

4 July 2018

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4 July 2018

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Gremlins, glomeruli and diabetic nephropathy

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865734

DRM/GREMLIN (CKTSF1B1) maps to human chromosome 15 and is highly expressed in adult and fetal brain

4 July 2018

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IHG-2, a mesangial cell gene induced by high glucose, is human gremlin. Regulation by extracellular glucose concentration, cyclic mechanical strain, and transforming growth factor-beta1

4 July 2018

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Control of vertebrate limb outgrowth by the proximal factor Meis2 and distal antagonism of BMPs by Gremlin

4 July 2018

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Suppression subtractive hybridization identifies high glucose levels as a stimulus for expression of connective tissue growth factor and other genes in human mesangial cells

4 July 2018

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The Xenopus dorsalizing factor Gremlin identifies a novel family of secreted proteins that antagonize BMP activities

4 July 2018

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Identification of drm, a novel gene whose expression is suppressed in transformed cells and which can inhibit growth of normal but not transformed cells in culture

4 July 2018

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The role of a single formin isoform in the limb and renal phenotypes of limb deformity

4 July 2018

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Coronary risk factors in schoolchildren

4 July 2018

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4 July 2018

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4 July 2018

1 reference

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Methylation status of CpG islands in the promoter regions of signature genes during chondrogenesis of human synovium-derived mesenchymal stem cells

4 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865734

Investigation of DNA polymorphisms in SMAD genes for genetic predisposition to diabetic nephropathy in patients with type 1 diabetes mellitus

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865734

The Notch pathway in podocytes plays a role in the development of glomerular disease

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865734

Impact of inflammation on epigenetic DNA methylation - a novel risk factor for cardiovascular disease?

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865734

Expression of gremlin, a bone morphogenetic protein antagonist, in human diabetic nephropathy

29 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2865734

Haplotype tagging for the identification of common disease genes

29 October 2018

1 reference

12 December 2020

Internet resources for the functional analysis of 5′ and 3′ untranslated regions of eukaryotic mRNAs

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12 December 2020

Expression of gremlin, a bone morphogenetic protein antagonist, in glomerular crescents of pauci-immune glomerulonephritis

1 reference

12 December 2020

Association of VEGF-1499C→T polymorphism with diabetic nephropathy in type 1 diabetes mellitus

1 reference

12 December 2020

Identifiers

DOI

10.1681/ASN.2009070773

1 reference

29 July 2017

1 reference

29 July 2017

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