Aberrant methylation of p16(INK4a) is an early event in lung cancer and a potential biomarker for early diagnosis (Q36324689)

13 August 2017

Aberrant methylation of p16(INK4a) is an early event in lung cancer and a potential biomarker for early diagnosis (English)

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13 August 2017

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1

S A Belinsky

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13 August 2017

2

K J Nikula

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13 August 2017

W A Palmisano

3

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13 August 2017

R Michels

4

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13 August 2017

G Saccomanno

5

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13 August 2017

E Gabrielson

6

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13 August 2017

S B Baylin

7

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13 August 2017

J G Herman

8

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13 August 2017

language of work or name

English

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publication date

1 September 1998

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13 August 2017

6

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Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

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13 August 2017

95

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13 August 2017

20

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13 August 2017

11891-11896

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Molecular damage in the bronchial epithelium of current and former smokers

13 August 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21736

Frequent aberrant methylation of p16INK4a in primary rat lung tumors

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21736

Detection of trisomy 7 in nonmalignant bronchial epithelium from lung cancer patients and individuals at risk for lung cancer

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21736

Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21736

A cell cycle regulator potentially involved in genesis of many tumor types

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21736

A prognostic model of recurrence and death in stage I non-small cell lung cancer utilizing presentation, histopathology, and oncoprotein expression.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21736

Reciprocal Rb inactivation and p16INK4 expression in primary lung cancers and cell lines.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21736

Lung carcinoma in former smokers.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21736

CDKN2 gene silencing in lung cancer by DNA hypermethylation and kinetics of p16INK4 protein induction by 5-aza 2'deoxycytidine.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21736

Development of carcinoma of the lung as reflected in exfoliated cells.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21736

Dose-response relationship between O6-methylguanine formation in Clara cells and induction of pulmonary neoplasia in the rat by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21736

Multiple K-ras codon 12 mutations in cholangiocarcinomas demonstrated with a sensitive polymerase chain reaction technique.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21736

5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21736

Rb and p16INK4a expression in resected non-small cell lung tumors.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21736

Examination of p53 alterations and cytokeratin expression in sputa collected from patients prior to histological diagnosis of squamous cell carcinoma

22 September 2018

1 reference

12 December 2020

Expression of early lung cancer detection marker p31 in neoplastic and non-neoplastic respiratory epithelium

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12 December 2020

Absence of p16INK4 protein is restricted to the subset of lung cancer lines that retains wildtype RB

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12 December 2020

Distinct patterns of inactivation of p15INK4B and p16INK4A characterize the major types of hematological malignancies

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12 December 2020

Clonal genetic alterations in the lungs of current and former smokers

1 reference

12 December 2020

Codeletion of p15 and p16 genes in primary non-small cell lung carcinoma

1 reference

12 December 2020

Deletion and differential expression of p16INK4a in mouse lung tumors

1 reference

12 December 2020

Changes in bronchial epithelium in relation to sex, age, residence, smoking and pneumonia

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.95.20.11891

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13 August 2017

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13 August 2017

PubMed publication ID

9751761

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