ERCC excision repair 2, TFIIH core complex helicase subunit (Q426168)

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mammalian protein found in humans
  • DNA repair protein complementing XP-D cells
  • excision repair cross-complementing rodent repair deficiency, complementation group 2
  • general transcription and DNA repair factor IIH helicase subunit XPD
  • CXPD
  • TFIIH basal transcription factor complex helicase subunit
  • basic transcription factor 2 80 kDa subunit
  • TFIIH 80 kDa subunit
  • TFIIH basal transcription factor complex helicase XPB subunit
  • xeroderma pigmentosum group D-complementing protein
  • xeroderma pigmentosum complementary group D
  • TFIIH basal transcription factor complex helicase XPD subunit
  • TFIIH p80
  • DNA excision repair protein ERCC-2
  • TFIIH basal transcription factor complex 80 kDa subunit
  • excision repair cross-complementation group 2
  • TFIIH subunit XPD
  • ERCC2
  • BTF2 p80
  • Xeroderma Pigmentosum Group D Protein
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Language Label Description Also known as
English
ERCC excision repair 2, TFIIH core complex helicase subunit
mammalian protein found in humans
  • DNA repair protein complementing XP-D cells
  • excision repair cross-complementing rodent repair deficiency, complementation group 2
  • general transcription and DNA repair factor IIH helicase subunit XPD
  • CXPD
  • TFIIH basal transcription factor complex helicase subunit
  • basic transcription factor 2 80 kDa subunit
  • TFIIH 80 kDa subunit
  • TFIIH basal transcription factor complex helicase XPB subunit
  • xeroderma pigmentosum group D-complementing protein
  • xeroderma pigmentosum complementary group D
  • TFIIH basal transcription factor complex helicase XPD subunit
  • TFIIH p80
  • DNA excision repair protein ERCC-2
  • TFIIH basal transcription factor complex 80 kDa subunit
  • excision repair cross-complementation group 2
  • TFIIH subunit XPD
  • ERCC2
  • BTF2 p80
  • Xeroderma Pigmentosum Group D Protein

Statements

molecular function
protein binding
determination method or standard
IPI
10 references
retrieved
8 April 2019
stated in
IOP1 protein is an external component of the human cytosolic iron-sulfur cluster assembly (CIA) machinery and functions in the MMS19 protein-dependent CIA pathway
GOA
curator
UniProt
UniProt protein ID
P18074
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18074
determination method or standard
IPI
retrieved
8 April 2019
stated in
Interactions involving the human RNA polymerase II transcription/nucleotide excision repair complex TFIIH, the nucleotide excision repair protein XPG, and Cockayne syndrome group B (CSB) protein
GOA
curator
UniProt
UniProt protein ID
P18074
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18074
determination method or standard
IPI
retrieved
8 April 2019
stated in
A yeast four-hybrid system identifies Cdk-activating kinase as a regulator of the XPD helicase, a subunit of transcription factor IIH
GOA
curator
UniProt
UniProt protein ID
P18074
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18074
determination method or standard
IPI
retrieved
8 April 2019
stated in
Human CIA2A-FAM96A and CIA2B-FAM96B integrate iron homeostasis and maturation of different subsets of cytosolic-nuclear iron-sulfur proteins
GOA
curator
UniProt
UniProt protein ID
P18074
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18074
determination method or standard
IPI
retrieved
8 April 2019
stated in
MMXD, a TFIIH-independent XPD-MMS19 protein complex involved in chromosome segregation
GOA
curator
UniProt
UniProt protein ID
P18074
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18074
determination method or standard
IPI
retrieved
8 April 2019
stated in
p53 modulation of TFIIH–associated nucleotide excision repair activity
GOA
curator
UniProt
UniProt protein ID
P18074
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18074
determination method or standard
IPI
retrieved
8 April 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18074
determination method or standard
IPI
retrieved
8 April 2019
stated in
Dynamic interaction of TTDA with TFIIH is stabilized by nucleotide excision repair in living cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18074
determination method or standard
IPI
retrieved
8 April 2019
stated in
The CIA Targeting Complex Is Highly Regulated and Provides Two Distinct Binding Sites for Client Iron-Sulfur Proteins
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18074
determination method or standard
IPI
retrieved
8 April 2019
stated in
Near-atomic resolution visualization of human transcription promoter opening
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18074
determination method or standard
IPI
cell component
nucleus
determination method or standard
IBA
IDA
IEA
6 references
retrieved
8 April 2019
stated in
GOA
curator
UniProt
UniProt protein ID
P18074
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18074
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
InterPro
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18074
determination method or standard
IEA
retrieved
8 April 2019
stated in
GOA
curator
Ensembl genome database project
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18074
determination method or standard
IEA
retrieved
8 April 2019
stated in
IOP1 protein is an external component of the human cytosolic iron-sulfur cluster assembly (CIA) machinery and functions in the MMS19 protein-dependent CIA pathway
GOA
curator
UniProt
UniProt protein ID
P18074
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18074
determination method or standard
IDA
retrieved
8 April 2019
stated in
MMXD, a TFIIH-independent XPD-MMS19 protein complex involved in chromosome segregation
GOA
curator
UniProt
UniProt protein ID
P18074
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18074
determination method or standard
IDA
retrieved
8 April 2019
stated in
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
GOA
curator
GO Central
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P18074
determination method or standard
IBA
biological process
Gene Atlas image
PBB GE ERCC2 213468 at fs.png
732 × 530; 11 KB
0 references

Identifiers

MeSH descriptor ID
D051759
subject named as
Xeroderma Pigmentosum Group D Protein
0 references
Freebase ID
/m/02pjd1t
0 references