Skp2-mediated degradation of p27 regulates progression into mitosis (Q47640200)

4 February 2018

title

Skp2-mediated degradation of p27 regulates progression into mitosis (English)

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4 February 2018

author

Yoji Andrew Minamishima

3

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4 February 2018

Shigetsugu Hatakeyama

6

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4 February 2018

author name string

Keiko Nakayama

1

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4 February 2018

Hiroyasu Nagahama

2

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4 February 2018

Satoshi Miyake

4

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4 February 2018

Noriko Ishida

5

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4 February 2018

Masatoshi Kitagawa

7

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4 February 2018

Shun-ichiro Iemura

8

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4 February 2018

Tohru Natsume

9

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4 February 2018

Keiichi I Nakayama

10

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4 February 2018

language of work or name

English

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publication date

1 May 2004

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4 February 2018

number of pages

12

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inferred from page(s)

published in

Developmental Cell

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4 February 2018

volume

6

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4 February 2018

issue

5

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4 February 2018

page(s)

661-672

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4 February 2018

SKP2 associates with p130 and accelerates p130 ubiquitylation and degradation in human cells

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7 January 2021

Role of the SCFSkp2 ubiquitin ligase in the degradation of p21Cip1 in S phase

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7 January 2021

SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

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7 January 2021

Degradation of B-Myb by ubiquitin-mediated proteolysis: involvement of the Cdc34-SCF(p45Skp2) pathway

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7 January 2021

Turnover of cyclin E by the ubiquitin-proteasome pathway is regulated by cdk2 binding and cyclin phosphorylation

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7 January 2021

CRM1/Ran-mediated nuclear export of p27(Kip1) involves a nuclear export signal and links p27 export and proteolysis

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2804%2900131-5

7 January 2021

p25rum1 orders S phase and mitosis by acting as an inhibitor of the p34cdc2 mitotic kinase

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2804%2900131-5

7 January 2021

Loss of Cul1 results in early embryonic lethality and dysregulation of cyclin E

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https://api.crossref.org/works/10.1016%2FS1534-5807%2804%2900131-5

7 January 2021

Endoreplication cell cycles: more for less

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7 January 2021

A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice

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7 January 2021

Stimulating effect of natural estrogens on proliferation of hepatocytes in adult mice

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7 January 2021

Degradation of p27(Kip1) at the G(0)-G(1) transition mediated by a Skp2-independent ubiquitination pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2804%2900131-5

7 January 2021

Ubiquitin-dependent degradation of IkappaBalpha is mediated by a ubiquitin ligase Skp1/Cul 1/F-box protein FWD1.

1 reference

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7 January 2021

Periodic expression of the cyclin-dependent kinase inhibitor p57(Kip2) in trophoblast giant cells defines a G2-like gap phase of the endocycle

1 reference

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7 January 2021

Translational control of p27Kip1 accumulation during the cell cycle

1 reference

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7 January 2021

Phosphorylation of p27Kip1 on serine 10 is required for its binding to CRM1 and nuclear export

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2804%2900131-5

7 January 2021

Degradation of p57Kip2 mediated by SCFSkp2-dependent ubiquitylation.

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2804%2900131-5

7 January 2021

Interaction between cyclin T1 and SCF(SKP2) targets CDK9 for ubiquitination and degradation by the proteasome

1 reference

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7 January 2021

Skp2 regulates Myc protein stability and activity

1 reference

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7 January 2021

An F-box protein, FWD1, mediates ubiquitin-dependent proteolysis of beta-catenin

1 reference

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7 January 2021

Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1).

1 reference

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7 January 2021

Phosphorylation-dependent ubiquitination of cyclin E by the SCFFbw7 ubiquitin ligase

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2804%2900131-5

7 January 2021

Fission yeast WD-repeat protein pop1 regulates genome ploidy through ubiquitin-proteasome-mediated degradation of the CDK inhibitor Rum1 and the S-phase initiator Cdc18.

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2804%2900131-5

7 January 2021

The SCF(Skp2) ubiquitin ligase complex interacts with the human replication licensing factor Cdt1 and regulates Cdt1 degradation

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2804%2900131-5

7 January 2021

Interaction between ubiquitin-protein ligase SCFSKP2 and E2F-1 underlies the regulation of E2F-1 degradation

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2804%2900131-5

7 January 2021

Human origin recognition complex large subunit is degraded by ubiquitin-mediated proteolysis after initiation of DNA replication

1 reference

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7 January 2021

Structure and expression of the gene encoding mouse F-box protein, Fwd2.

1 reference

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7 January 2021

Archipelago regulates Cyclin E levels in Drosophila and is mutated in human cancer cell lines

1 reference

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7 January 2021

Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2804%2900131-5

7 January 2021

Spatial and temporal expression patterns of the cyclin-dependent kinase (CDK) inhibitors p27Kip1 and p57Kip2 during mouse development

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2804%2900131-5

7 January 2021

Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2804%2900131-5

7 January 2021

Targeted disruption of Skp2 results in accumulation of cyclin E and p27(Kip1), polyploidy and centrosome overduplication

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2804%2900131-5

7 January 2021

Regulation of the cell cycle at the G1-S transition by proteolysis of cyclin E and p27Kip1.

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2804%2900131-5

7 January 2021

Cyclin-dependent kinases prevent DNA re-replication through multiple mechanisms

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2804%2900131-5

7 January 2021

Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2804%2900131-5

7 January 2021

p27 cytoplasmic localization is regulated by phosphorylation on Ser10 and is not a prerequisite for its proteolysis

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2804%2900131-5

7 January 2021

Cyclin E-CDK2 is a regulator of p27Kip1.

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2804%2900131-5

7 January 2021

Down-regulation of p27(Kip1) by two mechanisms, ubiquitin-mediated degradation and proteolytic processing

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2804%2900131-5

7 January 2021

Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2804%2900131-5

7 January 2021

A quantitative model for the cdc2 control of S phase and mitosis in fission yeast

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2804%2900131-5

7 January 2021

Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2804%2900131-5

7 January 2021

p45SKP2 promotes p27Kip1 degradation and induces S phase in quiescent cells

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2804%2900131-5

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2804%2900131-5

7 January 2021

The FT210 cell line is a mouse G2 phase mutant with a temperature-sensitive CDC2 gene product

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2804%2900131-5

7 January 2021

Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2804%2900131-5

7 January 2021

Mouse Fbw7/Sel-10/Cdc4 is required for notch degradation during vascular development.

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2804%2900131-5

7 January 2021

p27(Kip1) ubiquitination and degradation is regulated by the SCF(Skp2) complex through phosphorylated Thr187 in p27

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2804%2900131-5

7 January 2021

Phosphorylation-dependent degradation of the cyclin-dependent kinase inhibitor p27

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2804%2900131-5

7 January 2021

The F-box protein Skp2 participates in c-Myc proteosomal degradation and acts as a cofactor for c-Myc-regulated transcription

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2804%2900131-5

7 January 2021

Deletion of the Cul1 gene in mice causes arrest in early embryogenesis and accumulation of cyclin E

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2804%2900131-5

7 January 2021

Human CUL-1 associates with the SKP1/SKP2 complex and regulates p21(CIP1/WAF1) and cyclin D proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2804%2900131-5

7 January 2021

Polytene chromosomes in mammalian cells

1 reference

https://api.crossref.org/works/10.1016%2FS1534-5807%2804%2900131-5

7 January 2021

10.1016/S1534-5807(04)00131-5

Identifiers

DOI

1 reference

4 February 2018

1 reference

4 February 2018