CCR5
Tampilan
CCR5, (bahasa Inggris: chemokine receptor 5, CCR5) adalah pencerap kemokina dengan ligan, antara lain berupa RANTES, MIP-1
Referensi
[sunting | sunting sumber]- Wilkinson D (1997). "Cofactors provide the entry keys. HIV-1". Curr. Biol. 6 (9): 1051–3. PMID 8805353.
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- Sheppard HW, Celum C, Michael NL; et al. (2002). "HIV-1 infection in individuals with the CCR5-Delta32/Delta32 genotype: acquisition of syncytium-inducing virus at seroconversion". J. Acquir. Immune Defic. Syndr. 29 (3): 307–13. PMID 11873082.
- Freedman BD, Liu QH, Del Corno M, Collman RG (2004). "HIV-1 gp120 chemokine receptor-mediated signaling in human macrophages". Immunol. Res. 27 (2-3): 261–76. PMID 12857973.
- Esté JA (2004). "Virus entry as a target for anti-HIV intervention". Curr. Med. Chem. 10 (17): 1617–32. PMID 12871111.
- Gallo SA, Finnegan CM, Viard M; et al. (2003). "The HIV Env-mediated fusion reaction". Biochim. Biophys. Acta. 1614 (1): 36–50. PMID 12873764.
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- Lee C, Liu QH, Tomkowicz B; et al. (2004). "Macrophage activation through CCR5- and CXCR4-mediated gp120-elicited signaling pathways". J. Leukoc. Biol. 74 (5): 676–82. doi:10.1189/jlb.0503206. PMID 12960231.
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- Seibert C, Sakmar TP (2004). "Small-molecule antagonists of CCR5 and CXCR4: a promising new class of anti-HIV-1 drugs". Curr. Pharm. Des. 10 (17): 2041–62. PMID 15279544.
- Cutler CW, Jotwani R (2006). "Oral mucosal expression of HIV-1 receptors, co-receptors, and alpha-defensins: tableau of resistance or susceptibility to HIV infection?". Adv. Dent. Res. 19 (1): 49–51. PMID 16672549.
- Ajuebor MN, Carey JA, Swain MG (2006). "CCR5 in T cell-mediated liver diseases: what's going on?". J. Immunol. 177 (4): 2039–45. PMID 16887960.
- Lipp M, Müller G (2006). "Shaping up adaptive immunity: the impact of CCR7 and CXCR5 on lymphocyte trafficking". Verhandlungen der Deutschen Gesellschaft für Pathologie. 87: 90–101. PMID 16888899.
- Balistreri CR, Caruso C, Grimaldi MP; et al. (2007). "CCR5 receptor: biologic and genetic implications in age-related diseases". Ann. N. Y. Acad. Sci. 1100: 162–72. doi:10.1196/annals.1395.014. PMID 17460174.
- Madsen HO, Poulsen K, Dahl O; et al. (1990). "Retropseudogenes constitute the major part of the human elongation factor 1 alpha gene family". Nucleic Acids Res. 18 (6): 1513–6. PMID 2183196.
- Uetsuki T, Naito A, Nagata S, Kaziro Y (1989). "Isolation and characterization of the human chromosomal gene for polypeptide chain elongation factor-1 alpha". J. Biol. Chem. 264 (10): 5791–8. PMID 2564392.
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- Brands JH, Maassen JA, van Hemert FJ; et al. (1986). "The primary structure of the alpha subunit of human elongation factor 1. Structural aspects of guanine-nucleotide-binding sites". Eur. J. Biochem. 155 (1): 167–71. PMID 3512269.
Pranala luar
[sunting | sunting sumber]- Video and text from a PBS documentary about the discovery of CCR5
- IUPHAR GPCR Database - CCR5 Chemokine Receptor
- fact sheet: CCR5 receptor gene and HIV infection at CDC - (note, author is not a CDC employee, and there is no public domain notice on the page, so this cannot be assumed to be public domain)
- http://www.cdc.gov/genomics/hugenet/factsheets/FS_CCR5.htm 2% African American show CCR5 indicating extremely recent origin. Smallpox initiator suspect.
- Schering-Plough Initiates Phase III Studies with CCR5-Vicriviroc in Treatment- Experienced HIV Patients.