Pholedrine
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Clinical data | |
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Routes of administration | Topical (Ocular) |
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CompTox Dashboard (EPA) | |
ECHA InfoCard | 100.006.114 |
Chemical and physical data | |
Formula | C10H15NO |
Molar mass | 165.236 g·mol−1 |
3D model (JSmol) | |
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Pholedrine (Paredrinol, Pulsotyl, Veritol), also known as 4-hydroxy-N-methylamphetamine (4-HMA), 4-hydroxymethamphetamine, and para-hydroxymethamphetamine,[1] is a drug that stimulates the sympathetic nervous system.[2] It is administered as a topical eye drop form for the purpose of dilating the pupil and can be used to diagnose Horner's syndrome.[2]
4-hydroxymethamphetamine is also a major metabolite of methamphetamine.
See also
References
- ^ "Pholedrine". National Library of Medicine. Retrieved 24 June 2023.
- ^ a b Bates AT, Chamberlain S, Champion M, Foley L, Hughes E, Jani B, et al. (February 1995). "Pholedrine: a substitute for hydroxyamphetamine as a diagnostic eyedrop test in Horner's syndrome". Journal of Neurology, Neurosurgery, and Psychiatry. 58 (2): 215–7. doi:10.1136/jnnp.58.2.215. PMC 1073320. PMID 7876854.
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