topos (n.)

type of abnormal hypersensitiveness, 1923, coined by Edward D. Perry, professor of Greek at Columbia University, at the request of medical men, from Greek atopia "unusualness, strangeness, a being out of the way," from atopos "out of place, strange, odd, eccentric," from a- "not, without" (see a- (3)) + topos "place" (see topos).

"imaginary bad place," 1952, from dys- "bad, abnormal" + ending abstracted from utopia. Earlier in medical use, "displacement of an organ" (by 1844), with second element from Greek topos "place" (see topos). Dystopian was used in the non-medical sense in 1868 by J.S. Mill:

I may be permitted, as one who, in common with many of my betters, have been subjected to the charge of being Utopian, to congratulate the Government on having joined that goodly company. It is, perhaps, too complimentary to call them Utopians, they ought rather to be called dys-topians, cacotopians. What is commonly called Utopian is something too good to be practicable; but what they appear favour is too bad to be practicable. [speech, March 12, 1868]