(Translated by https://www.hiragana.jp/)
Nuclear factor of activated T cells 3 - Wikidata

Nuclear factor of activated T cells 3 (Q21124063)

From Wikidata

Jump to navigation Jump to search

mammalian protein found in Homo sapiens

T cell transcription factor NFAT4
NF-ATc3
nuclear factor of activated T-cells, cytoplasmic 3
nuclear factor of activated T-cells c3 isoform IE-Xa
NF-AT4
NFATx
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NFATC3
T-cell transcription factor NFAT4

Language	Label	Description	Also known as
English	Nuclear factor of activated T cells 3	mammalian protein found in Homo sapiens	T cell transcription factor NFAT4 NF-ATc3 nuclear factor of activated T-cells, cytoplasmic 3 nuclear factor of activated T-cells c3 isoform IE-Xa NF-AT4 NFATx nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 NFATC3 T-cell transcription factor NFAT4

Statements

1 reference

13 November 2019

UniProt protein ID

p53-like transcription factor, DNA-binding

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q12968

Immunoglobulin-like fold

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q12968

Nuclear factor of activated T cells (NFAT)

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q12968

Rel homology domain (RHD), DNA-binding domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q12968

Immunoglobulin E-set

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q12968

IPT domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Rel homology dimerisation domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Rel homology domain (RHD), DNA-binding domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

13 November 2019

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

molecular function

determination method

2 references

DNA-binding transcription factor activity

determination method

1 reference

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12968&geneProductId=UniProtKB:Q12968

determination method

DNA-binding transcription activator activity, RNA polymerase II-specific

determination method

4 references

10 September 2018

Nuclear factor of activated T cells regulates transcription of the surfactant protein D gene (Sftpd) via direct interaction with thyroid transcription factor-1 in lung epithelial cells

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12968&geneProductId=UniProtKB:Q12968

determination method

10 September 2018

Nuclear factor of activated T cells regulates transcription of the surfactant protein D gene (Sftpd) via direct interaction with thyroid transcription factor-1 in lung epithelial cells

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12968&geneProductId=UniProtKB:Q12968

determination method

8 April 2019

Nuclear factor of activated T cells regulates transcription of the surfactant protein D gene (Sftpd) via direct interaction with thyroid transcription factor-1 in lung epithelial cells

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12968

determination method

8 April 2019

Nuclear factor of activated T cells regulates transcription of the surfactant protein D gene (Sftpd) via direct interaction with thyroid transcription factor-1 in lung epithelial cells

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12968

determination method

RNA polymerase II cis-regulatory region sequence-specific DNA binding

determination method

1 reference

24 April 2018

Nuclear factor of activated T cells regulates transcription of the surfactant protein D gene (Sftpd) via direct interaction with thyroid transcription factor-1 in lung epithelial cells

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12968&geneProductId=UniProtKB:Q12968

determination method

protein binding

determination method

1 reference

8 April 2019

Nuclear Raf-1 kinase regulates the CXCR5 promoter by associating with NFATc3 to drive retinoic acid-induced leukemic cell differentiation

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12968

determination method

DNA-binding transcription repressor activity, RNA polymerase II-specific

determination method

1 reference

8 April 2019

MicroRNA-26 governs profibrillatory inward-rectifier potassium current changes in atrial fibrillation

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12968

determination method

DNA-binding transcription factor activity, RNA polymerase II-specific

determination method

3 references

8 April 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12968

determination method

8 April 2019

A census of human transcription factors: function, expression and evolution

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12968

determination method

8 April 2019

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12968

determination method

RNA polymerase II cis-regulatory region sequence-specific DNA binding

determination method

2 references

8 April 2019

Nuclear factor of activated T cells regulates transcription of the surfactant protein D gene (Sftpd) via direct interaction with thyroid transcription factor-1 in lung epithelial cells

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12968

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12968

determination method

chromatin binding

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12968

determination method

transcription factor binding

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12968

determination method

determination method

2 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12968

determination method

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12968

determination method

determination method

4 references

24 April 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12968&geneProductId=UniProtKB:Q12968

determination method

24 April 2018

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12968&geneProductId=UniProtKB:Q12968

determination method

24 April 2018

CHP2 activates the calcineurin/nuclear factor of activated T cells signaling pathway and enhances the oncogenic potential of HEK293 cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12968&geneProductId=UniProtKB:Q12968

determination method

24 April 2018

Targeted disruption of NFATc3, but not NFATc4, reveals an intrinsic defect in calcineurin-mediated cardiac hypertrophic growth

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12968&geneProductId=UniProtKB:Q12968

determination method

determination method

determination method

5 references

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12968

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12968

determination method

8 April 2019

CHP2 activates the calcineurin/nuclear factor of activated T cells signaling pathway and enhances the oncogenic potential of HEK293 cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12968

determination method

8 April 2019

Targeted disruption of NFATc3, but not NFATc4, reveals an intrinsic defect in calcineurin-mediated cardiac hypertrophic growth

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12968

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12968

determination method

transcription regulator complex

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12968

determination method

determination method

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12968

determination method

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12968

determination method

8 April 2019

Human Protein Atlas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12968

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12968

determination method

biological process

regulation of transcription, DNA-templated

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12968

determination method

regulation of transcription by RNA polymerase II

determination method

1 reference

8 April 2019

Isolation of two new members of the NF-AT gene family and functional characterization of the NF-AT proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12968

determination method

transcription by RNA polymerase II

determination method

1 reference

8 April 2019

NFATx, a novel member of the nuclear factor of activated T cells family that is expressed predominantly in the thymus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12968

determination method

transcription, DNA-templated

determination method

1 reference

24 April 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12968&geneProductId=UniProtKB:Q12968

determination method

positive regulation of transcription, DNA-templated

determination method

1 reference

8 April 2019

Ensembl genome database project

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12968

determination method

Fc-epsilon receptor signaling pathway

determination method

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12968

determination method

inflammatory response

determination method

1 reference

8 April 2019

NFATx, a novel member of the nuclear factor of activated T cells family that is expressed predominantly in the thymus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12968

determination method

positive regulation of transcription by RNA polymerase II

determination method

2 references

24 April 2018

Nuclear factor of activated T cells regulates transcription of the surfactant protein D gene (Sftpd) via direct interaction with thyroid transcription factor-1 in lung epithelial cells

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12968&geneProductId=UniProtKB:Q12968

determination method

24 April 2018

CHP2 activates the calcineurin/nuclear factor of activated T cells signaling pathway and enhances the oncogenic potential of HEK293 cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q12968&geneProductId=UniProtKB:Q12968

determination method

negative regulation of pri-miRNA transcription by RNA polymerase II

determination method

1 reference

8 April 2019

MicroRNA-26 governs profibrillatory inward-rectifier potassium current changes in atrial fibrillation

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12968

determination method

negative regulation of vascular associated smooth muscle cell differentiation

determination method

1 reference

8 April 2019

MicroRNA-124 suppresses the transactivation of nuclear factor of activated T cells by targeting multiple genes and inhibits the proliferation of pulmonary artery smooth muscle cells

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12968

determination method

cytokine production

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12968

determination method

calcineurin-NFAT signaling cascade

determination method

1 reference

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12968

determination method

positive regulation of transcription by RNA polymerase II

determination method

3 references

8 April 2019

Nuclear factor of activated T cells regulates transcription of the surfactant protein D gene (Sftpd) via direct interaction with thyroid transcription factor-1 in lung epithelial cells

Norwegian University of Science and Technology, Systems Biology team

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12968

determination method

8 April 2019

CHP2 activates the calcineurin/nuclear factor of activated T cells signaling pathway and enhances the oncogenic potential of HEK293 cells

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12968

determination method

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12968

determination method

multicellular organism development

determination method

1 reference

8 April 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q12968

determination method

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q12968

Rel homology dimerisation domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q12968

Rel homology domain (RHD), DNA-binding domain

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/Q12968

Identifiers

RefSeq protein ID

1 reference

30 May 2020

1 reference

30 May 2020

1 reference

30 May 2020

UniProt protein ID

1 reference

13 November 2019

UniProt protein ID

Ensembl protein ID

ENSP00000264008

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000264008

ENSP00000300659

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000300659

ENSP00000331324

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000331324

ENSP00000445670

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000445670

ENSP00000454451

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000454451

ENSP00000455113

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000455113

ENSP00000456120

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000456120

ENSP00000456307

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000456307

ENSP00000456379

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000456379

ENSP00000457441

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000457441

ENSP00000460533

1 reference

Ensembl Release 99

Ensembl protein ID

ENSP00000460533

PDB structure ID

1 reference

UniProt protein ID

9 August 2016

language of work or name

1 reference

UniProt protein ID

9 August 2016

language of work or name

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q21124063&oldid=2023001784"