AT-076
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Formula | C26H35N3O3 |
Molar mass | 437.584 g·mol−1 |
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AT-076 is a so-called opioid "pan" antagonist and is the first reasonably balanced antagonist known of all four opioid receptor types.[1] It acts as a silent antagonist of all four of the opioid receptors, behaving as a competitive antagonist of the
See also
[edit]References
[edit]- ^ a b c Zaveri NT, Journigan VB, Polgar WE (2015). "Discovery of the First Small-Molecule Opioid Pan Antagonist with Nanomolar Affinity at Mu, Delta, Kappa, and Nociceptin Opioid Receptors". ACS Chem Neurosci. 6 (4): 646–57. doi:10.1021/cn500367b. PMC 4401318. PMID 25635572.