EA-2192
Appearance
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Names | |
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Preferred IUPAC name
S-{2-[Di(propan-2-yl)amino]ethyl} methylphosphonothioate | |
Other names
Diisopropylaminoethyl methyl thiolophosphonate
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Identifiers | |
3D model (JSmol)
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ChemSpider | |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C9H22NO2PS | |
Molar mass | 239.31 g·mol−1 |
Appearance | White solid |
Very soluble | |
Hazards | |
Occupational safety and health (OHS/OSH): | |
Main hazards
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Extremely toxic |
Lethal dose or concentration (LD, LC): | |
LD50 (median dose)
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630 18 50 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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EA-2192 is an extremely toxic degradation product of the VX nerve agent.[1][2] It is a white solid that is very soluble and stable in water.
EA-2192 is an extremely potent acetylcholinesterase inhibitor. It is almost as toxic as VX itself.[3]
EA-2192 behaves similar to aged Soman as it is the dealkylated form of VX and cannot be reversed with common oxime reactivators.
![](https://upload.wikimedia.org/wikipedia/commons/thumb/1/1d/VX-solvolysis-P-O-2D-skeletal.png/400px-VX-solvolysis-P-O-2D-skeletal.png)
See also
[edit]References
[edit]- ^ Ellison, D. Hank (2007). Handbook of chemical and biological warfare agents (2nd ed.). Boca Raton, Fla.: CRC. ISBN 9780849314346.
- ^ Hoenig, Steven L. (2007), Compendium of Chemical Warfare Agents, Springer, ISBN 978-0-387-34626-7
- ^ Munro, NB; Talmage, SS; Griffin, GD; Waters, LC; Watson, AP; King, JF; Hauschild, V (December 1999). "The sources, fate, and toxicity of chemical warfare agent degradation products". Environmental Health Perspectives. 107 (12): 933–74. doi:10.1289/ehp.99107933. PMC 1566810. PMID 10585900.