Phosalone
Names | |
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Preferred IUPAC name
S-[(6-Chloro-2-oxo-1,3-benzoxazol-3(2H)-yl)methyl] O,O-diethyl phosphorodithioate | |
Other names
Zolone
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Identifiers | |
3D model (JSmol)
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ChEBI | |
ChEMBL | |
ChemSpider | |
ECHA InfoCard | 100.017.270 |
KEGG | |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C12H15ClNO4PS2 | |
Molar mass | 367.80 g·mol−1 |
Appearance | Colorless crystalline |
Odor | garlic |
Density | 1.39 g cm−3 |
Melting point | 47.5 to 48 °C (117.5 to 118.4 °F; 320.6 to 321.1 K) |
3.05 mg/L | |
Solubility | many organic solvents |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Phosalone is an organophosphate chemical commonly used as an insecticide and acaricide. It is developed by Rhône-Poulenc in France but EU eliminated it from pesticide registration in December 2006.
The median lethal dose of oral exposure in rat is 85 mg/kg and that of dermal is 390 mg/kg.[1]。It is a weak acetylcholinesterase inhibitor.[2] It is taken by not only oral and inhalation but skin and it causes toxic symptoms peculiar to organophosphorus compounds such as miosis, hypersalivation, hyperhidrosis, chest pressure, pulmonary edema and fecal incontinence.[3] It is flammable and decomposes to toxic gases such as phosphorus oxides, sulfur oxides and nitrogen oxides.[2] It is harmful especially to water creatures.
References[edit]
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製品 安全 データシート(安全 衛生 情報 センター) Archived 2014-10-25 at the Wayback Machine - ^ a b "
国際 化学 物質 安全 性 カード". Archived from the original on 2012-12-11. Retrieved 2012-09-06. - ^
植村 振作 ・河村 宏 ・辻 万 千 子 ・冨田 重行 ・前田 静夫 著 (2002).農薬 毒性 の事典 改訂 版 .三省堂 . ISBN 978-4385356044.
External links[edit]
- Phosalone Fact Sheet
- EPA Webpage on Phosolone
- Phosalone in the Pesticide Properties DataBase (PPDB)