ωおめが-6脂肪酸しぼうさん

ωおめが-6脂肪酸しぼうさん是ぜ一いち個こ多元たげん不ふ飽和ほうわ脂肪酸しぼうさん系列けいれつ，它屬於必需ひつじゅ脂肪酸しぼうさん（essential fatty acids），必須ひっす由ゆかり食物しょくもつ中ちゅう取得しゅとく，無法むほう在ざい人體じんたい內自行ぎょう合成ごうせい。

健康けんこう的てき負まけ面めん影響えいきょう

一いち些醫學がく研究けんきゅう表明ひょうめい，超過ちょうか於一定いってい含量的てきΩおめが-6脂肪酸しぼうさん：Ωおめが-3脂肪酸しぼうさん比ひ值，可能かのう會かい增加ぞうか一いち些疾病的びょうてき機き率りつ。^[1]^[2]^[3] 現代げんだい西方せいほう飲食いんしょく兩者りょうしゃ之の間あいだ的てき比ひ值通常つうじょう超過ちょうか 10比ひ1，有ゆう的てき甚至高だか達たち 30比ひ1。最さい佳けい比例ひれい被ひ認みとめ為ため是ぜ4比ひ1或ある更さら低ひく。^[4]^[5]

過か量的りょうてきΩおめが-6脂肪酸しぼうさん會かい干ひ擾Ωおめが-3脂肪酸しぼうさん對たい健康けんこう的てき益えき處しょ，因いん為ため他た們爭奪そうだつ相しょう同どう的てき限きり速そく酶。過か高こう的てきΩおめが-6脂肪酸しぼうさん：Ωおめが-3脂肪酸しぼうさん比ひ值，轉移てんい了りょう組織そしき對たい許多きょた疾病しっぺい發病はつびょう機き制せい的てき生理せいり狀態じょうたい，比ひ如血栓けっせん、炎症えんしょう等ひとし。^[6]

長期ちょうき超ちょう量的りょうてきΩおめが-6脂肪酸しぼうさん会かい引起慢性まんせい心臟しんぞう病びょう發作ほっさ、血栓けっせん性せい中風ちゅうぶ、心こころ律りつ不整ふせい、關節かんせつ炎えん、骨質こっしつ疏鬆症しょう、發はつ炎症えんしょう、情緒じょうちょ障礙しょうがい、肥こえ胖ゆたか與あずか癌がん症しょう等とう疾病しっぺい。^[7] 用よう於治療ちりょう這些疾病しっぺい的てき藥物やくぶつ，通常つうじょう是ぜ有效ゆうこう的てき通過つうか阻斷Ωおめが-6脂肪酸しぼうさん中ちゅう的てき花はな生せい四よん烯酸来らい完成かんせい的てき。^[8]從したがえ花はな生せい四烯酸形成激素的很多步驟，比ひ從したがえΩおめが-3脂肪酸しぼうさん的てき二に十じゅう碳五烯酸所ところ形成けいせい的てき激げき素もと更さら加か强きょう勁。^[9]

注ちゅう释

^ Lands, William E.M. Dietary fat and health: the evidence and the politics of prevention: careful use of dietary fats can improve life and prevent disease. Annals of the New York Academy of Sciences (Blackwell). December 2005, 1055: 179–192. PMID 16387724. doi:10.1196/annals.1323.028.
^ Hibbeln, Joseph R.; Nieminen, Levi R.G.; Blasbalg, Tanya L.; Riggs, Jessica A.; Lands, William E. M. Healthy intakes of n−3 and n−6 fatty acids: estimations considering worldwide diversity. American Journal of Clinical Nutrition (American Society for Nutrition). 1 June 2006, 83 (6, supplement): 1483S–1493S [2011年ねん10月がつ15日にち]. PMID 16841858. （原始げんし内容ないよう存そん档于2010年ねん6月がつ25日にち）.
^ Okuyama, Hirohmi; Ichikawa, Yuko; Sun, Yueji; Hamazaki, Tomohito; Lands, William E. M. ωおめが3 fatty acids effectively prevent coronary heart disease and other late-onset diseases: the excessive linoleic acid syndrome. World Review of Nutritional Dietetics. World Review of Nutrition and Dietetics (Karger). 2007, 96 (Prevention of Coronary Heart Disease): 83–103. ISBN 3805581793. PMID 17167282. doi:10.1159/000097809.
^ Daley, C. A.; Abbott, A.; Doyle, P.; Nader, G.; and Larson, S. A literature review of the value-added nutrients found in grass-fed beef products. California State University, Chico (College of Agriculture). 2004 [2008-03-23]. （原始げんし内容ないよう存そん档于2008-07-06）.
^ Simopoulos, Artemis P. The importance of the ratio of omega-6/omega-3 essential fatty acids. Biomedicine & Pharmacotherapy. October 2002, 56 (8): 365–379. PMID 12442909. doi:10.1016/S0753-3322(02)00253-6.
^ Simopoulos, Artemis P. Importance of the ratio of omega-6/omega-3 essential fatty acids: evolutionary aspects. World Review of Nutrition and Dietetics. World Review of Nutrition and Dietetics (Karger). September 2003, 92 (Omega–6/Omega–3 Essential Fatty Acid Ratio: The Scientific Evidence): 1–174. ISBN 3805576404. PMID 14579680. doi:10.1159/000073788.
^ Calder, Philip C. n−3 polyunsaturated fatty acids, inflammation, and inflammatory diseases. American Journal of Clinical Nutrition (American Society for Nutrition). 1 June 2006, 83 (6, supplement): 1505S–1519S [2011年ねん10月がつ15日にち]. PMID 16841861. （原始げんし内容ないよう存そん档于2010年ねん10月がつ30日にち）.
^ Smith, William L. Nutritionally essential fatty acids and biologically indispensable cyclooxygenases. Trends in Biochemical Sciences (Elsevier). January 2008, 33 (1): 27–37. PMID 18155912. doi:10.1016/j.tibs.2007.09.013.
^ Wada, M.; Delong, CJ; Hong, YH; Rieke, CJ; Song, I; Sidhu, RS; Yuan, C; Warnock, M; Schmaier, AH. Enzymes and receptors of prostaglandin pathways with arachidonic acid-derived versus eicosapentaenoic acid-derived substrates and products. Nutritionally essential fatty acids and biologically indispensable cyclooxygenases. J. Biol. Chem. (ASBMB). August 3, 2007, 282 (31): 22254–22266. PMID 17519235. doi:10.1074/jbc.M703169200.

[Lands2005-1] Lands, William E.M. Dietary fat and health: the evidence and the politics of prevention: careful use of dietary fats can improve life and prevent disease. Annals of the New York Academy of Sciences (Blackwell). December 2005, 1055: 179–192. PMID 16387724. doi:10.1196/annals.1323.028.

[Hibbeln2006-2] Hibbeln, Joseph R.; Nieminen, Levi R.G.; Blasbalg, Tanya L.; Riggs, Jessica A.; Lands, William E. M. Healthy intakes of n−3 and n−6 fatty acids: estimations considering worldwide diversity. American Journal of Clinical Nutrition (American Society for Nutrition). 1 June 2006, 83 (6, supplement): 1483S–1493S [2011年ねん10月がつ15日にち]. PMID 16841858. （原始げんし内容ないよう存そん档于2010年ねん6月がつ25日にち）.

[Okuyama2007-3] Okuyama, Hirohmi; Ichikawa, Yuko; Sun, Yueji; Hamazaki, Tomohito; Lands, William E. M. ωおめが3 fatty acids effectively prevent coronary heart disease and other late-onset diseases: the excessive linoleic acid syndrome. World Review of Nutritional Dietetics. World Review of Nutrition and Dietetics (Karger). 2007, 96 (Prevention of Coronary Heart Disease): 83–103. ISBN 3805581793. PMID 17167282. doi:10.1159/000097809.

[daley2004-4] Daley, C. A.; Abbott, A.; Doyle, P.; Nader, G.; and Larson, S. A literature review of the value-added nutrients found in grass-fed beef products. California State University, Chico (College of Agriculture). 2004 [2008-03-23]. （原始げんし内容ないよう存そん档于2008-07-06）.

[simopoulos2002-5] Simopoulos, Artemis P. The importance of the ratio of omega-6/omega-3 essential fatty acids. Biomedicine & Pharmacotherapy. October 2002, 56 (8): 365–379. PMID 12442909. doi:10.1016/S0753-3322(02)00253-6.

[simopoulos2003-6] Simopoulos, Artemis P. Importance of the ratio of omega-6/omega-3 essential fatty acids: evolutionary aspects. World Review of Nutrition and Dietetics. World Review of Nutrition and Dietetics (Karger). September 2003, 92 (Omega–6/Omega–3 Essential Fatty Acid Ratio: The Scientific Evidence): 1–174. ISBN 3805576404. PMID 14579680. doi:10.1159/000073788.

[Calder2006-7] Calder, Philip C. n−3 polyunsaturated fatty acids, inflammation, and inflammatory diseases. American Journal of Clinical Nutrition (American Society for Nutrition). 1 June 2006, 83 (6, supplement): 1505S–1519S [2011年ねん10月がつ15日にち]. PMID 16841861. （原始げんし内容ないよう存そん档于2010年ねん10月がつ30日にち）.

[Smith2008-8] Smith, William L. Nutritionally essential fatty acids and biologically indispensable cyclooxygenases. Trends in Biochemical Sciences (Elsevier). January 2008, 33 (1): 27–37. PMID 18155912. doi:10.1016/j.tibs.2007.09.013.

[Wada_2007-9] Wada, M.; Delong, CJ; Hong, YH; Rieke, CJ; Song, I; Sidhu, RS; Yuan, C; Warnock, M; Schmaier, AH. Enzymes and receptors of prostaglandin pathways with arachidonic acid-derived versus eicosapentaenoic acid-derived substrates and products. Nutritionally essential fatty acids and biologically indispensable cyclooxygenases. J. Biol. Chem. (ASBMB). August 3, 2007, 282 (31): 22254–22266. PMID 17519235. doi:10.1074/jbc.M703169200.

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