TAS2R46

味あじ觉感受かんじゅ器き，类型2，成なり员46
味あじ觉感受かんじゅ器き，类型2，成なり员46
标识
代だい号ごう	TAS2R46; T2R46; T2R54
扩展标识	遗传学がく：612774 鼠ねずみ基もと因いん：2681256 同どう源みなもと基はじめ因いん：131216 IUPHAR: GeneCards: TAS2R46 Gene
基もと因いん本体ほんたい论描述じゅつ
分子ぶんし功こう能のう	· G-protein coupled receptor activity;
细胞成分せいぶん	· integral to membrane; · cilium membrane;
生物せいぶつ过程	· sensory perception of taste;
	Sources: Amigo / QuickGO
直系ちょっけい同どう源みなもと体たい
物もの种	人ひと类
Entrez	259292
Ensembl	ENSG00000226761
UniProt	P59540
mRNA序列じょれつ	NM_176887
蛋白たんぱく序列じょれつ	NP_795368
基もと因いん位置いち	Chr 12:; 11.21 – 11.21 Mb
PubMed查询	[1]
	查; 论; 编;

味あじ觉感受かんじゅ器き，类型2，成なり员46，TAS2R46 是ぜ一个人类基因组中TAS2R46基もと因いん编码的てき蛋白たんぱく质，是ぜ苦く味あじ味あじ觉感受かんじゅ器き的てき一いち员。^[1]^[2]

另见

^ Bufe B, Hofmann T, Krautwurst D, Raguse JD, Meyerhof W. The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides. Nat Genet. Oct 2002, 32 (3): 397–401. PMID 12379855. doi:10.1038/ng1014.
^ Entrez Gene: TAS2R46 taste receptor, type 2, member 46.

Margolskee RF. Molecular mechanisms of bitter and sweet taste transduction.. J. Biol. Chem. 2002, 277 (1): 1–4. PMID 11696554. doi:10.1074/jbc.R100054200.
Montmayeur JP, Matsunami H. Receptors for bitter and sweet taste.. Curr. Opin. Neurobiol. 2002, 12 (4): 366–71. PMID 12139982. doi:10.1016/S0959-4388(02)00345-8.
Strausberg RL, Feingold EA, Grouse LH; et al. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.. Proc. Natl. Acad. Sci. U.S.A. 2003, 99 (26): 16899–903. PMC 139241 . PMID 12477932. doi:10.1073/pnas.242603899.
Zhang Y, Hoon MA, Chandrashekar J; et al. Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways.. Cell. 2003, 112 (3): 293–301. PMID 12581520. doi:10.1016/S0092-8674(03)00071-0.
Conte C, Ebeling M, Marcuz A; et al. Identification and characterization of human taste receptor genes belonging to the TAS2R family.. Cytogenet. Genome Res. 2003, 98 (1): 45–53. PMID 12584440. doi:10.1159/000068546.
Fischer A, Gilad Y, Man O, Pääbo S. Evolution of bitter taste receptors in humans and apes.. Mol. Biol. Evol. 2005, 22 (3): 432–6. PMID 15496549. doi:10.1093/molbev/msi027.
Go Y, Satta Y, Takenaka O, Takahata N. Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates.. Genetics. 2006, 170 (1): 313–26. PMC 1449719 . PMID 15744053. doi:10.1534/genetics.104.037523.