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Gene Symbol(s):
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Rela
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| Organism: |
Mus musculus |
| View Gene in Tree |
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| Gene Name: |
Transcription factor p65
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| Gene ID: |
MGI:103290
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| Protein ID: |
Q04207
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| Persistent Id: |
PTN000652530 |
| Alternate Ids: |
| 19697(GeneID) |
417926(GI) |
| Nfkb3(Synonym) |
CHEMBL5902(ChEMBL) |
| M61909(EMBL) |
Rela(Symbol) |
| ENSMUSG00000024927(Ensembl) |
AAB00795(EMBL-CDS) |
| TF65_MOUSE(UniProtKB-ID) |
Q62025(AltAccession) |
MGI:103290(MGI) |
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Show All
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| GO MF Complete: |
RNA polymerase II core promoter sequence-specific DNA binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, double-stranded DNA binding, RNA polymerase II transcription regulatory region sequence-specific DNA binding, transcription cis-regulatory region binding, DNA-binding transcription activator activity, RNA polymerase II-specific, sequence-specific DNA binding, peptide binding, DNA-binding transcription repressor activity, RNA polymerase II-specific, transcription coactivator binding, protein-containing complex binding, DNA-binding transcription factor activity, ankyrin repeat binding, general transcription initiation factor binding, DNA-binding transcription factor binding, transcription regulator activity, chromatin DNA binding, protein kinase binding, identical protein binding, protein homodimerization activity, histone deacetylase binding, actinin binding, chromatin binding, phosphate ion binding, DNA-binding transcription factor activity, RNA polymerase II-specific, NF-kappaB binding, DNA binding, ubiquitin protein ligase binding, protein binding, enzyme binding
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| GO BP Complete: |
negative regulation of angiogenesis, response to muramyl dipeptide, positive regulation of non-canonical NF-kappaB signal transduction, negative regulation of protein catabolic process, negative regulation of non-canonical NF-kappaB signal transduction, chromatin organization, positive regulation of NF-kappaB transcription factor activity, defense response to tumor cell, inflammatory response, hair follicle development, negative regulation of DNA-templated transcription, positive regulation of DNA-templated transcription, cellular response to biotic stimulus, response to muscle stretch, intracellular signal transduction, positive regulation of miRNA metabolic process, positive regulation of vascular endothelial growth factor production, cellular response to angiotensin, response to organic substance, toll-like receptor 4 signaling pathway, non-canonical NF-kappaB signal transduction, positive regulation of amyloid-beta formation, negative regulation of insulin receptor signaling pathway, animal organ morphogenesis, tumor necrosis factor-mediated signaling pathway, neuropeptide signaling pathway, positive regulation of interleukin-8 production, nucleotide-binding oligomerization domain containing 2 signaling pathway, positive regulation of gene expression, response to interleukin-1, regulation of inflammatory response, positive regulation of interleukin-6 production, response to UV-B, response to cytokine, negative regulation of miRNA transcription, positive regulation of cell population proliferation, positive regulation of canonical NF-kappaB signal transduction, positive regulation of Schwann cell differentiation, positive regulation of miRNA transcription, positive regulation of leukocyte adhesion to vascular endothelial cell, positive regulation of transcription by RNA polymerase II, negative regulation of transcription by RNA polymerase II, cellular response to interleukin-6, cytokine-mediated signaling pathway, liver development, cellular response to stress, postsynapse to nucleus signaling pathway, cellular response to tumor necrosis factor, negative regulation of protein sumoylation, cellular response to hydrogen peroxide, cellular response to nicotine, DNA-templated transcription, protein catabolic process, prolactin signaling pathway, vascular endothelial growth factor signaling pathway, regulation of DNA-templated transcription, defense response, canonical NF-kappaB signal transduction, regulation of transcription by RNA polymerase II, positive regulation of T cell receptor signaling pathway, response to bacterium, positive regulation of interleukin-12 production, cellular response to lipopolysaccharide, cellular response to lipoteichoic acid, cellular response to hepatocyte growth factor stimulus, innate immune response, negative regulation of apoptotic process, cellular response to interleukin-1, negative regulation of extrinsic apoptotic signaling pathway, interleukin-1-mediated signaling pathway, cellular response to peptidoglycan, positive regulation of chondrocyte differentiation, positive regulation of interleukin-1 beta production
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| GO CC Complete: |
nucleus, transcription regulator complex, cytoplasm, NF-kappaB p50/p65 complex, cytosol, protein-containing complex, NF-kappaB complex, glutamatergic synapse, synapse, chromatin
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| Reactome Pathways: |
Immune System, Toll Like Receptor TLR1:TLR2 Cascade, ZBP1(DAI) mediated induction of type I IFNs, Toll Like Receptor 5 (TLR5) Cascade, Toll-like Receptor Cascades, Toll Like Receptor 9 (TLR9) Cascade, Regulated proteolysis of p75NTR, Chromatin modifying enzymes, Interleukin-1 processing, Signaling by the B Cell Receptor (BCR), NF-kB is activated and signals survival, SUMOylation, Innate Immune System, Downstream TCR signaling, Signal Transduction, CD209 (DC-SIGN) signaling, MyD88 cascade initiated on plasma membrane, MyD88 dependent cascade initiated on endosome, TAK1-dependent IKK and NF-kappa-B activation , DDX58/IFIH1-mediated induction of interferon-alpha/beta, Toll Like Receptor 2 (TLR2) Cascade, Fc epsilon receptor (FCERI) signaling, Signaling by Interleukins, Cytokine Signaling in Immune system, Downstream signaling events of B Cell Receptor (BCR), Toll Like Receptor 3 (TLR3) Cascade, SUMOylation of immune response proteins, Adaptive Immune System, Post-translational protein modification, SUMO E3 ligases SUMOylate target proteins, TRAF6 mediated NF-kB activation, Toll Like Receptor 4 (TLR4) Cascade, DEx/H-box helicases activate type I IFN and inflammatory cytokines production , MyD88:MAL(TIRAP) cascade initiated on plasma membrane, Cytosolic sensors of pathogen-associated DNA , TRIF(TICAM1)-mediated TLR4 signaling , Activation of NF-kappaB in B cells, Interleukin-1 signaling, CLEC7A (Dectin-1) signaling, p75 NTR receptor-mediated signalling, Death Receptor Signaling, MyD88-independent TLR4 cascade , Toll Like Receptor TLR6:TLR2 Cascade, Chromatin organization, Interleukin-1 family signaling, TCR signaling, FCERI mediated NF-kB activation, RIP-mediated NFkB activation via ZBP1, C-type lectin receptors (CLRs), TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation, Toll Like Receptor 7/8 (TLR7/8) Cascade, PKMTs methylate histone lysines, Toll Like Receptor 10 (TLR10) Cascade, Metabolism of proteins, p75NTR signals via NF-kB
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