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Gene Symbol(s):
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RELA
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| Organism: |
Sus scrofa |
| View Gene in Tree |
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| Gene Name: |
RELA proto-onco, NF-kB subunit
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| Gene ID: |
ENSSSCG00000012981.6
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| Protein ID: |
F6PVF4
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| Persistent Id: |
PTN001539207 |
| Alternate Ids: |
| ENSSSCG00000012981(Ensembl) |
F6PVF4(Synonym) |
| ENSSSCT00000014191(Ensembl_TRS) |
ENSSSCP00000013805(Ensembl_PRO) |
| DQIR01087852(EMBL) |
F6PVF4_PIG(UniProtKB-ID) |
HDB21609(EMBL-CDS) |
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Show All
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| GO MF Complete: |
protein kinase binding, chromatin DNA binding, protein homodimerization activity, histone deacetylase binding, actinin binding, RNA polymerase II core promoter sequence-specific DNA binding, RNA polymerase II cis-regulatory region sequence-specific DNA binding, DNA-binding transcription activator activity, RNA polymerase II-specific, peptide binding, DNA-binding transcription repressor activity, RNA polymerase II-specific, phosphate ion binding, DNA-binding transcription factor activity, RNA polymerase II-specific, transcription coactivator binding, NF-kappaB binding, ubiquitin protein ligase binding, ankyrin repeat binding, general transcription initiation factor binding
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| GO BP Complete: |
negative regulation of angiogenesis, response to muramyl dipeptide, positive regulation of non-canonical NF-kappaB signal transduction, negative regulation of protein catabolic process, negative regulation of non-canonical NF-kappaB signal transduction, chromatin organization, defense response to tumor cell, inflammatory response, hair follicle development, response to muscle stretch, positive regulation of vascular endothelial growth factor production, cellular response to angiotensin, toll-like receptor 4 signaling pathway, non-canonical NF-kappaB signal transduction, positive regulation of amyloid-beta formation, animal organ morphogenesis, neuropeptide signaling pathway, positive regulation of interleukin-8 production, tumor necrosis factor-mediated signaling pathway, nucleotide-binding oligomerization domain containing 2 signaling pathway, regulation of inflammatory response, positive regulation of interleukin-6 production, response to UV-B, response to cytokine, negative regulation of miRNA transcription, positive regulation of cell population proliferation, positive regulation of canonical NF-kappaB signal transduction, positive regulation of miRNA transcription, positive regulation of leukocyte adhesion to vascular endothelial cell, positive regulation of transcription by RNA polymerase II, negative regulation of transcription by RNA polymerase II, cellular response to interleukin-6, liver development, cellular response to stress, negative regulation of protein sumoylation, postsynapse to nucleus signaling pathway, cellular response to hydrogen peroxide, cellular response to nicotine, DNA-templated transcription, protein catabolic process, vascular endothelial growth factor signaling pathway, prolactin signaling pathway, canonical NF-kappaB signal transduction, positive regulation of T cell receptor signaling pathway, positive regulation of interleukin-12 production, cellular response to lipopolysaccharide, cellular response to lipoteichoic acid, cellular response to hepatocyte growth factor stimulus, innate immune response, negative regulation of extrinsic apoptotic signaling pathway, interleukin-1-mediated signaling pathway, cellular response to peptidoglycan, positive regulation of interleukin-1 beta production
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| GO CC Complete: |
nucleus, transcription regulator complex, cytoplasm, NF-kappaB p50/p65 complex, cytosol, glutamatergic synapse, chromatin
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| Reactome Pathways: |
DDX58/IFIH1-mediated induction of interferon-alpha/beta, CD209 (DC-SIGN) signaling, MyD88 cascade initiated on plasma membrane, TCR signaling, Signal Transduction, NF-kB is activated and signals survival, Metabolism of proteins, Post-translational protein modification, Toll Like Receptor 3 (TLR3) Cascade, Fc epsilon receptor (FCERI) signaling, Signaling by Interleukins, TAK1-dependent IKK and NF-kappa-B activation , Innate Immune System, ZBP1(DAI) mediated induction of type I IFNs, Downstream signaling events of B Cell Receptor (BCR), SUMOylation of immune response proteins, Death Receptor Signaling, Regulated proteolysis of p75NTR, MyD88:MAL(TIRAP) cascade initiated on plasma membrane, Toll Like Receptor 4 (TLR4) Cascade, MyD88 dependent cascade initiated on endosome, DEx/H-box helicases activate type I IFN and inflammatory cytokines production , Toll Like Receptor 2 (TLR2) Cascade, TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation, Activation of NF-kappaB in B cells, Downstream TCR signaling, p75 NTR receptor-mediated signalling, Cytokine Signaling in Immune system, Adaptive Immune System, Chromatin organization, Toll Like Receptor 10 (TLR10) Cascade, Interleukin-1 family signaling, Toll Like Receptor TLR6:TLR2 Cascade, TRAF6 mediated NF-kB activation, MyD88-independent TLR4 cascade , SUMO E3 ligases SUMOylate target proteins, CLEC7A (Dectin-1) signaling, FCERI mediated NF-kB activation, TRIF(TICAM1)-mediated TLR4 signaling , C-type lectin receptors (CLRs), RIP-mediated NFkB activation via ZBP1, SUMOylation, Toll Like Receptor 7/8 (TLR7/8) Cascade, PKMTs methylate histone lysines, p75NTR signals via NF-kB, Toll Like Receptor 5 (TLR5) Cascade, Immune System, Toll Like Receptor TLR1:TLR2 Cascade, Interleukin-1 signaling, Toll-like Receptor Cascades, Toll Like Receptor 9 (TLR9) Cascade, Chromatin modifying enzymes, Cytosolic sensors of pathogen-associated DNA , Interleukin-1 processing, Signaling by the B Cell Receptor (BCR)
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