RXFP receptor

RXFP1, or the relaxin family peptide receptor 1, functions as the receptor for relaxin-2, exerting a pivotal influence on the regulation of reproductive and cardiovascular physiology. Recognized as a prominent therapeutic target, RXFP1 holds significance for its substantial impact on various physiological processes. Structurally, RXFP1 is identified as a multi-domain G protein-coupled receptor (GPCR) characterized by an ectodomain that includes an LDLa module and leucine-rich repeats. This intricate structural arrangement underscores the crucial role of RXFP1 in mediating the biological effects of relaxin-2, positioning it as a key player in both physiological and therapeutic contexts.